Qualidade de Vida de Sobreviventes de Câncer de Mama do Chile: Estudo Multicêntrico

Autores

DOI:

https://doi.org/10.32635/2176-9745.RBC.2023v69n1.2757

Palavras-chave:

neoplasias da mama, qualidade de vida, determinantes sociais da saúde, sobreviventes de câncer, promoção da saúde

Resumo

Introdução: À medida que as taxas de sobrevivência do câncer de mama aumentam, também aumenta a necessidade de melhorar a qualidade de vida relacionada à saúde (QVRS) dos sobreviventes. Objetivo: Analisar a QVRS em geral e considerando a localização geográfica entre sobreviventes de câncer de mama chilenas. Além disso, correlacionar a QVRS com idade, nível educacional e índice de massa corporal (IMC). Método: Estudo observacional transversal que incluiu 125 mulheres sobreviventes de câncer de mama de três hospitais públicos em três Macrorregiões chilenas: Central, Norte-Central e Sul. Foram utilizados os Questionários EORTC QLQ-C30 e QLQ-BR23 e os registros sociodemográficos e clínicos. Resultado: A média de idade foi de 56,1 (±11,9) anos com escore resumido de QVRS de 67,6 (21,9). A QVRS estava reduzida principalmente no funcionamento emocional, dor e insônia. Fadiga, dispneia, perda de apetite, constipação, dificuldades financeiras, sintomas de braço e mama também foram mencionados. As mulheres do hospital da Macrorregião Sul apresentaram os piores escores de QVRS para a maioria dos domínios [saúde geral, funcionamento (físico, emocional, cognitivo e social), fadiga e náusea], p<0,001. A pontuação geral de QVRS esteve correlacionada com idade (rho de Spearman=0,202, p=0,033), IMC (rho=-0,341, p<0,001) e nível educacional (rho=0,310, p=0,001). Conclusão: As mulheres das três Macrorregiões apresentaram diferenças na QVRS. Esta última se correlacionou com idade, IMC e nível educacional. Considerando a alta presença de sintomas, há necessidade de aprimoramento dos planos de atenção à sobrevivência, possibilitando acesso à reabilitação no contínuo do cuidado.

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Referências

Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. doi: https://doi.org/10.3322/caac.21492 DOI: https://doi.org/10.3322/caac.21492

Tao ZQ, Shi A, Lu C, et al. Breast cancer: epidemiology and etiology. Cell Biochem Biophys. 2015;72(2):333-8. doi: https://doi.org/10.1007/s12013-014-0459-6 DOI: https://doi.org/10.1007/s12013-014-0459-6

Ministerio de Salud (CL), Subsecretaría de Salud Pública, División de prevención y Control de Enfermedades, Departamento Manejo Integral del Cáncer y otros Tumores. Guías clínicas AUGE: cáncer de mama. Santiago (CL): Minsal; 2015.

Miller AM, Ashing KT, Modeste NN, et al. Contextual factors influencing health-related quality of life in African American and Latina breast cancer survivors. J Cancer Surviv. 2015;9(3):441-9. doi: https://doi.org/10.1007/s11764-014-0420-0 DOI: https://doi.org/10.1007/s11764-014-0420-0

Sibhat SG, Fenta TG, Sander B, et al. Health-related quality of life and its predictors among patients with breast cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Health Qual Life Outcomes. 2019;17(1):165. doi: https://doi.org/10.1186/s12955-019-1239-1 DOI: https://doi.org/10.1186/s12955-019-1239-1

Sitlinger A, Zafar SY. Health-related quality of life: the impact on morbidity and mortality. Surg Oncol Clin N Am. 2018;27(4):675-84. doi: https://doi.org/10.1016/j.soc.2018.05.008 DOI: https://doi.org/10.1016/j.soc.2018.05.008

Graells-Sans A, Serral G, Puigpinós-Riera R. Social inequalities in quality of life in a cohort of women diagnosed with breast cancer in Barcelona (DAMA Cohort). Cancer Epidemiol. 2018;54:38-47. doi: https://doi.org/10.1016/j.canep.2018.03.007 DOI: https://doi.org/10.1016/j.canep.2018.03.007

Fischer MJ, Inoue K, Matsuda A, et al. Cross-cultural comparison of breast cancer patients’ quality of life in the Netherlands and Japan. Breast Cancer Res Treat. 2017;166(2):459-71. doi: https://doi.org/10.1007/s10549-017-4417-z DOI: https://doi.org/10.1007/s10549-017-4417-z

Di Meglio A, Michiels S, Jones LW, et al. Changes in weight, physical and psychosocial patient-reported outcomes among obese women receiving treatment for early-stage breast cancer: a nationwide clinical study. Breast. 2020;52:23-32. doi: https://doi.org/10.1016/j.breast.2020.04.002 DOI: https://doi.org/10.1016/j.breast.2020.04.002

Wang L, Guyatt GH, Kennedy SA, et al. Predictors of persistent pain after breast cancer surgery: a systematic review and meta-analysis of observational studies. CMAJ. 2016;188(14):E352-E61. doi: https://doi.org/10.1503/cmaj.151276 DOI: https://doi.org/10.1503/cmaj.151276

Nguyen-Pham S, Leung J, McLaughlin D. Disparities in breast cancer stage at diagnosis in urban and rural adult women: a systematic review and meta-analysis. Ann Epidemiol. 2014;24(3):228-35. doi: https://doi.org/10.1016/j.annepidem.2013.12.002 DOI: https://doi.org/10.1016/j.annepidem.2013.12.002

Andrade MC, Ribeiro AP, Lanza K, et al. Ações de detecção precoce do câncer de mama no brasil: análise dos dados do sistema de informação do controle do câncer de mama (Sismama), 2009-2015. Rev Bras Cancerol. 2022;68(3):e-082189. doi: https://doi.org/10.32635/2176-9745.rbc.2022v68n3.2189 DOI: https://doi.org/10.32635/2176-9745.RBC.2022v68n3.2189

Gonzalez L, Bardach A, Palacios A, et al. Health-related quality of life in patients with breast cancer in latin america and the caribbean: a systematic review and meta-analysis. Oncologist. 2021;26(5):e794-e806. doi: https://doi.org/10.1002/onco.13709 DOI: https://doi.org/10.1002/onco.13709

Jiménez D, Lavados M, Rojas P, et al. Evaluación del minimental abreviado de la evaluación funcional del adulto mayor (EFAM) como screening para la detección de demencia en la atención primaria. Rev Med Chil. 2017;145(7):862-8. doi: http://doi.org/10.4067/s0034-98872017000700862 DOI: https://doi.org/10.4067/s0034-98872017000700862

Ministerio de Salud (CL). Plan Nacional de Cáncer 2018-2028 [Internet]. Santiago (CL): Ministerio de Salud; 2018 [acesso 2022 mar 10]. Disponível em: https://www.minsal.cl/wp-content/uploads/2019/01/2019.01.23_PLAN-NACIONAL-DE-CANCER_web.pdf

Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365-76. doi: https://doi.org/10.1093/jnci/85.5.365 DOI: https://doi.org/10.1093/jnci/85.5.365

Irarrázaval ME, Rodríguez PF, Fasce G, et al. Calidad de vida en cancer de mama: validacion del cuestionario BR23 en Chile. Rev Med Chil. 2013;141(6):723-34. doi: https://doi.org/10.4067/S0034-98872013000600006 DOI: https://doi.org/10.4067/S0034-98872013000600006

Husson O, de Rooij BH, Kieffer J, et al. The EORTC QLQ-C30 summary score as prognostic factor for survival of patients with cancer in the “Real-World”: results from the population-based PROFILES registry. Oncologist. 2020;25(4):e722-e32. doi: https://doi.org/10.1634/theoncologist.2019-0348 DOI: https://doi.org/10.1634/theoncologist.2019-0348

Imran M, Al-Wassia R, Alkhayyat SS, et al. Assessment of quality of life (QoL) in breast cancer patients by using EORTC QLQ-C30 and BR-23 questionnaires: a tertiary care center survey in the western region of Saudi Arabia. PLoS One. 2019;14(7):e0219093. doi: https://doi.org/10.1371/journal.pone.0219093 DOI: https://doi.org/10.1371/journal.pone.0219093

El Fakir S, El Rhazi K, Zidouh A, et al. Health-related quality of life among breast cancer patients and influencing factors in Morocco. Asian Pac J Cancer Prev. 2016;17(12):5063-9. doi: https://doi.org/10.22034/APJCP.2016.17.12.5063

Agide FD, Sadeghi R, Garmaroudi G, et al. A systematic review of health promotion interventions to increase breast cancer screening uptake: from the last 12 years. Eur J Public Health. 2018;28(6):1149-1155. doi: https://doi.org/10.1093/eurpub/ckx231 DOI: https://doi.org/10.1093/eurpub/ckx231

Mokhtari-Hessari P, Montazeri A. Health-related quality of life in breast cancer patients: review of reviews from 2008 to 2018. Health Qual Life Outcomes. 2020;18(1):338. doi: https://doi.org/10.1186/s12955-020-01591-x DOI: https://doi.org/10.1186/s12955-020-01591-x

Kwak A, Jacobs J, Haggett D, et al. Evaluation and management of insomnia in women with breast cancer. Breast Cancer Res Treat. 2020;181(2):269-77. doi: https://doi.org/10.1007/s10549-020-05635-0 DOI: https://doi.org/10.1007/s10549-020-05635-0

Jiang M, Ma Y, Yun B, et al. Exercise for fatigue in breast cancer patients: an umbrella review of systematic reviews. Int J Nurs Sci. 2020;7(2):248-54. doi: https://doi.org/10.1016/j.ijnss.2020.03.001 DOI: https://doi.org/10.1016/j.ijnss.2020.03.001

Ma Y, Hall DL, Ngo LH, et al. Efficacy of cognitive behavioral therapy for insomnia in breast cancer: a meta-analysis. Sleep Med Rev. 2021;55:101376. doi: https://doi.org/10.1016/j.smrv.2020.101376 DOI: https://doi.org/10.1016/j.smrv.2020.101376

Ministerio de Salud (CL), Departamento de Epidemiología, División de Planificación Sanitaria, Subsecretaría de Salud Pública. Encuesta Nacional de Salud 2016-2017 [Internet]. Santiago (CL): Ministerio de Salud; 2017 [acesso 2022 mar 10]. Disponível em: https://www.minsal.cl/wp-content/uploads/2017/11/ENS-2016-17_PRIMEROS-RESULTADOS.pdf

Observatorio Chileno de Salud Publica [Internet]. Santiago (CL): OCHISAP; [data desconhecida]. Nivel socioeconómico y de salud de las comunas de Chile; [2013]. [acesso 2022 mar 10]. Disponível em: http://www.ochisap.cl/index.php/nivel-socioeconomico-y-de-salud-de-las-comunas-de-chile

You J, Wang C, Yeung NCY, et al. Socioeconomic status and quality of life among Chinese American breast cancer survivors: the mediating roles of social support and social constraints. Psychooncology. 2018;27(7):1742-9. doi: https://doi.org/10.1002/pon.4719 DOI: https://doi.org/10.1002/pon.4719

Galiano-Castillo N, Cantarero-Villanueva I, Fernández-Lao C, et al. Telehealth system: a randomized controlled trial evaluating the impact of an internet-based exercise intervention on quality of life, pain, muscle strength, and fatigue in breast cancer survivors. Cancer. 2016;122(20):3166-74. doi: https://doi.org/10.1002/cncr.30172 DOI: https://doi.org/10.1002/cncr.30172

Publicado

2022-12-06

Como Citar

1.
Lorca LA, Sacomori C, Vera-Llanos S, Hinrichsen-Ramírez AE, López K, Vega M, Contalba P, Sperandio FF. Qualidade de Vida de Sobreviventes de Câncer de Mama do Chile: Estudo Multicêntrico. Rev. Bras. Cancerol. [Internet]. 6º de dezembro de 2022 [citado 1º de fevereiro de 2023];69(1):e-022757. Disponível em: https://rbc.inca.gov.br/index.php/revista/article/view/2757

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