Epidermoid carcinoma of the female urethra associated with human papillomavirus: a case report

Authors

  • Ernani Luís Rhoden Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA). Santa Casa de Misericórdia de Porto Alegre (ISCMPA). Porto Alegre (RS), Brasil
  • José Carlos Souto Hospital da Irmandade da Santa Casa de Misericórdia de Porto Alegre (ISCMPA). Porto Alegre (RS), Brasil
  • Luís Antônio Macedo Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA). Porto Alegre (RS), Brasil
  • Antônio Hartmann Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA). Porto Alegre (RS), Brasil
  • Cláudio Telöken Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA). Porto Alegre (RS), Brasil
  • Carlos Ari Vargas Souto Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA). Santa Casa de Misericórdia de Porto Alegre (ISCMPA). Porto Alegre (RS), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1997v43n3.2850

Keywords:

Urethral Carcinoma, Epidermoid Carcinoma, Human Papillomavirus, Urinary Reservoir

Abstract

Primary cancer of the female urethra is a rare malignant neoplasm. The authors report a case of a 32-year-old black female patient who came to the medical center with urinary obstruction. Diagnostic investigation showed urethral epidermoid carcinoma as the subjacent cause of the symptom. Radical cystourethrectomy combined with pelvic lymphadenectomy, total hysterectomy, and resection of the anterior vaginal wall with reconstruction of the urinary tract with a continente urinary reservoir (Indiana Pouch Surgery) were performed. A positive reaction, at the immunohistochemical study, for human papillomavirus (HPV) antigen was observed in the tumor. Now, after 12 months offollow-up, the patient is disease-free and has good quality of life.

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References

Hahn, P.; Krepart, G.; Malaker, K.- Carcinoma of female urethra. Manitoba experience: 1958-1987. Urology 37(2): 106-9,1991. DOI: https://doi.org/10.1016/0090-4295(91)80202-I

Wiener, J.S.; Walther, P.J. - A high association of oncogenic human papilloma-viruses with carcinomas of the female urethra: polymerase chain reaction-based analysis of multiple histological types. J Urol, 151:49-53,1994. DOI: https://doi.org/10.1016/S0022-5347(17)34870-X

Barrasso, R.; De Brux J.; Croissant, O.; Orth, G.- High prevalence of papilloma-virus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia. N E J Med, 37(15): 916-23,1987. DOI: https://doi.org/10.1056/NEJM198710083171502

Wiener,J.S.; Walther, P.J.-The association of oncogenic human pappilomaviruses with urologic malignancy. Surg Oncol Clin N Am, 4(2): 257-76,1995. DOI: https://doi.org/10.1016/S1055-3207(18)30452-6

Wiener, J.S.; Liu, E.T.; Walther, P.J.- Oncogenic human papillomavirus type 16 associated with squamous cell câncer of the male urethra. Câncer Research, 52: 5018- 22,1992.

Villla, L.L.; Lopes, A.- Human papiloma virus DNA sequences in penile carcinomas in Brazil. Int J Cancer, 37: 853-55, 1986. DOI: https://doi.org/10.1002/ijc.2910370610

Grigsby, P.W.; Corn, B.W.-Localized urethral tumors in women: indications for conservative versus exenterati ve therapies. JUrol., 147: 1516-20, 1992 DOI: https://doi.org/10.1016/S0022-5347(17)37614-0

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Published

2022-09-27

How to Cite

1.
Rhoden EL, Souto JC, Macedo LA, Hartmann A, Telöken C, Souto CAV. Epidermoid carcinoma of the female urethra associated with human papillomavirus: a case report. Rev. Bras. Cancerol. [Internet]. 2022 Sep. 27 [cited 2024 Jul. 22];43(3):187-90. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/2850

Issue

Vol. 43 No. 3 (1997): July/Aug./Sept.

Section

CASE REPORT

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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