Efeitos Carcinogênicos de Baixas Doses de Radiação
DOI:
https://doi.org/10.32635/2176-9745.RBC.1985v31n4.3365Keywords:
Low Dose Radiation, CarcinogenesisAbstract
The studies of several groups of epidemiologists on the effects of low doses of radiation to the whole body is presented. The results of such studies show that the radiation effects in man can be represented graphicaly in three differents manners: linear, supralinear and infralinear, when a direct relationship between dose and development of cancer is considered. The author offers a brief review of the carcinogenic effects of medical applications of ionizing radiation since the beginning of this century.
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References
Committee for the Compilation on Material on Damage Caused by the Atomic Bombs in Hiiroshima and Nagasaki. The physical, medical and social effects of the atomic bombings. New York, Basic Books, 1981.
Committee on the Biological Effects of Ionizing Radiations. The effects on populations of exposure to low leveis of ionizing radiation (BEIR III). Washington DC, National Academy of Sciences, 1980.
Court Brown WN, Doll R: Expectation of life and mortality from câncer among British radiologists. British Medicai Journal, 1958;2: 181-7. DOI: https://doi.org/10.1136/bmj.2.5090.181
Doll R: Radiationhazards:25yearsofcollaborativeresearch. British Journal of Radiology, 1981; 54: 179-186. DOI: https://doi.org/10.1259/0007-1285-54-639-179
Duniap CE: Effects of radiation on the blood and hemopoietic tissues, including the spleen, the thymus and the lymph nodes. Archives of Pathology, 1942; 34: 562.
Frieben: Cancroid des rechten Handrückens. Deutsche Medizinische Wochenchrift, 1902; 28 (Suppiement): 334.
Henshaw PS, et al: Incidence of leukemia in physicians. Journal of the National Cancer Institute, 1944; 4: 339.
Hesse O.: Das Rõntgenkarzinom. Fortschritte auf dem Gebiete. Rõntgenstrahien und der Nuklearmedizin, 1911; 15:82.
Mac Mahon HE, et al: Endothelial-cell sarcoma of liver following throtrast injections. American Journal of Patholo gy, 1947; 23: 585.
March HC; Leukemia in radiologists. Radiology, 1944; 43: 275. DOI: https://doi.org/10.1148/43.3.275
Mori T: Pathological and radiological studies of chronic tho rotrast injury. Part 1. Study of human materiais. Nippon Acta Radiologica, 1966; 26: 1028.
National Council on Radiation Protection and Measure ments. The influence of dose and its distribution in time on dose effect relationships for low LET radiation. Report 64. Washington DC: NCRP, 1980.
Pochin EE, et al: Leukaemia following radioiodine treatment of hyperthyroidism. British Journal of Radiology, 1956; 29:31. DOI: https://doi.org/10.1259/0007-1285-29-337-31
Simpson CL, et al: Neoplasia in children treated with x-rays in infancy for thymus enlargement Radiology, 1955; 64: 840. DOI: https://doi.org/10.1148/64.6.840
Sinclair WH: Effects of low-level radiation and comparativa risk. Radiology, 1981; 138:1-9. [ DOI: https://doi.org/10.1148/radiology.138.1.7005937
Smith PG, Doll R: Age and time-dependent changes in the rates of radiation-induced cancers in patients with ankylosing spondylitis following a single course of x-ray treatment. Late Biological Effects of ionizing Radiation. Vol. 1, Inter national Atomic Energy Authority, Vienna, 1978; p. 205- 218.
Smith PG, Doll R: Mortality from cancer and all causes among British radiologists. British Journal of Radiology, 1981; 54: 187-194. DOI: https://doi.org/10.1259/0007-1285-54-639-187
Stewart AM, et al; Malignant disease in childhood and diagnostic radiation in utero. Lancet, 1956; 2: 447. DOI: https://doi.org/10.1016/S0140-6736(56)91923-7
Stewart AM, Kneale GM: Changes in cancer risk associated with obstetric radiography. Lancet, 1968; 1; 104-7, DOI: https://doi.org/10.1016/S0140-6736(68)92719-0
Takahashi, et al: Statistical study on human cancer induced by medicai irradiation Nippon Acta Radiologica, 1964; 23: 1510.
United Nations Scientific Committee on the Effects of Atomic Radiation. Ionizing radiation: Biological effects. United Nations, New York, 1977.
Upton AC: The biological effects of low-level, ionizing ra diation. Scientific American, 1982; 246(2): 29-37. DOI: https://doi.org/10.1038/scientificamerican0282-41
Wohlwill F: Üntersuchugen über die Gewebesreaktion auf thorotrast. Schweizerische Zeitschrift fur Allgemeine Pathologie, 1942; 5: 21. DOI: https://doi.org/10.1159/000159279
Rowland RE, et al: Dose-reponse relationships for female radium dial workers. Radiation Research, 1978; 76: 368- 383. DOI: https://doi.org/10.2307/3574786
