Antimetastatic and Cytostatic Effects of Phospholipids Combined With Insulin and Alloxan

Authors

  • Reinout F. A. Altman Instituto Oswaldo Cruz. Rio de Janeiro, GB. Brasil
  • Luiz G. Spoladore Instituto Oswaldo Cruz. Rio de Janeiro, GB. Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1968v24n38.4012

Keywords:

Neoplasms/etiology, Neoplasms/therapy, Phospholipids/therapeutic use, Insulin, Alloxan, Sarcoma, Yoshida

Abstract

Basing themselves on certain existing relations between cancer and diabetes, the authors attempted to combine in an adequate manner the beneficent action of phospholipids with that of insulin. The experimental results were surprisingly favourable for it could be stated that the growth of the transplanted Yoshida sarcoma was inhibited completely in not less than 60 per cent of the treated animais, whereas in the remaining 40 per cent the growth was reduced to less than half. Alloxan, although in a lesser degree, showed similar favourable results when combined with phospholipids.

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References

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Published

2023-08-18

How to Cite

1.
Altman RFA, Spoladore LG. Antimetastatic and Cytostatic Effects of Phospholipids Combined With Insulin and Alloxan. Rev. Bras. Cancerol. [Internet]. 2023 Aug. 18 [cited 2024 Jul. 3];24(38):83-7. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4012

Issue

Section

ORIGINAL ARTICLE