Associação Radioterapia e Quimioterapia

Authors

  • M. O. Roxo Nobre Diretor. Departamento de Radioterapia. Instituto Central do Hospital A. C. Camargo. São Paulo (SP), Brasil
  • Renato R. A Cintra Chefe. Serviço de Radioterapia. Instituto Central do Hospital A. C. Camargo; Hospital do Servidor Público Estadual do Estado de São Paulo. São Paulo (SP), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1967v23n33.4032

Keywords:

Radiotherapy, Drug Therapy, Infusions, Intra-Arterial, Bone Neoplasms/therapy, Head and Neck Neoplasms/therapy, Uterine Cervical Neoplasms/therapy

Abstract

The authors present clinical experiments which are being done by the radiotherapy and chemotherapy association, through arterial infusion in tumours of head and neck and tumours of the bones. In gynecology similar association is perfomed by means of the introduction of chemotherapeutic agentes into the uterine cavity during the treatment with radium in advanced cases of the cancer of the cervix. This material, whose observation has been developed for 2 years, does not yet allow statistic conclusions although it justifies the pursuit the method for its preliminary results. Its is advised against indiscriminate indication of the preliminary treatment of chemotherapy in the most diverse forms of malignant tumours, which is being done, chiefly by indications of physicians who have little experience in oncological matter. In cases in which the conventional treatment by surgery or radiotherapy offer satisfactory results, the previous chemotherapy may yield therapeutical inconveniences. Chemotherapy in association with irradiation or surgery should be used by prescription and assistance of a medical team.

Downloads

Download data is not yet available.

References

CAPELLANO, R.: Quimioterapia Antineoplásica por infusão arterial. Indicações para o tratamento dos tumores da cabeça e pescoço. Rev. Bras. Cir. 46 — 5, 358-359, nov. 1963.

CAPPELLANO, R.; Técnica de infusão intra-arterial contínua de Quimioterápicos para tratamento das neoplasias malignas da cabeça e do pescoço. Rev. Bras. Cir. 46 — 6, 405-410, dez. 1963

CURRERI, A. R., WORKERS, C. D.: Estudos clínicos com o 5 Fu. Câncer Research, vol. 18, 478-482, mai 1958.

D’ANZIO, G. J.: Potentiation of X-rays effects by Actinomycin D. Radiology. vol. 78, n.° 2, aug. 1959. DOI: https://doi.org/10.1148/73.2.175

FLETCHER, G. H.; HERMAN, D. S. e col.: Clinical method of testing radiation sensitizing agents in squamous cell carcinoma. Câncer. 16: 355-363, march 1963. DOI: https://doi.org/10.1002/1097-0142(196303)16:3<355::AID-CNCR2820160310>3.0.CO;2-L

HELSLER, J. T.; SHAPP, G. S.: Combination therapy with 5 Fu and Co60 for inoperable carcinoma of the lungs. Câncer Chemother. Report, 20 julho 1962.

JUNQUEIRA, A. C. C.: A associação radioterapia e quimioterapia no tratamento do câncer. Rev. Bras. Cir. vol. 42, n° 6, 303-309, dezembro 1961.

JUNQUEIRA, A. C. C.: Quimioterapia antineoplásica. Finalidade de seu emprego em associação com a cirurgia e a radioterapia. Rev. Paul. Med. vol. 62, n° 6, 480-490, junho 1963.

KARNOFSKY, D.: Câncer Chemotherapeutic agents. Câncer, vol. 11, n.° 2, 58-66, march-april, 1961. DOI: https://doi.org/10.3322/canjclin.11.2.58

KAPLAN, H. S.; ZAVARINE, R. e EAOLE, J.: Interaction of oxygen effect and radiosensivization produced by base analogues incorporeted into deoxy ribonucleic acid in — Year Book of Câncer, pag. 432, 1962-1963.

KLIGERMAN., MORTOM, M.: The role of combination radiation and chemoterapy. Conference on Research on the Radiotherapy of Câncer. American Câncer Society Inc. 147 — 157, 1960. DOI: https://doi.org/10.1002/1097-0142(196011/12)13:6+<147::AID-CNCR2820130724>3.0.CO;2-N

KREMENTZ, E. T.: SCHLOSSER, J. V.; RUMAGE, J. P.: Retinoblastoma. Behavior and treatment with fractional irradiation and intra-arterial Triethylenemelamine. An. New York Ac. of Sc. 114 — 2, 963-975, april 1964. DOI: https://doi.org/10.1111/j.1749-6632.1964.tb41017.x

LOKEN MERLE, K.: The effect of combined irradiation and chemoterapy on câncer growth with special reference to studies with folie acid antagonists. Radiology, vol. 73, n.° 2, aug. 1959 DOI: https://doi.org/10.1148/73.2.166

MITCHELL. J. s. e col.: An attempt to develop a radioactivo drug for Cancer Chemotherapy on the treatment of Câncer. Cambridge University Press, 1965.

PARISI, ELOY.: Tratamento quimioterápico das neoplasias malignas. Rev. Bras. Cir. vol. 40, n° 5, 382-389, novembro 1960.

RAMOS JR. J.: A quimioterapia no tratamento das neoplasias malignas. Rev. Bras. de Cir. vol. 40 n.° 5, 370-381, novembro 1960.

SANTOS Silva, M.: Tratamento de vários tipos de tumores sólidos com infusão contínua intra-arterial de Methotexate associada à administração simultânea e descontínua do fator citrovorum e complementação pelo Telecobaltoterapia. Rev. Bras. Cancerol. vol. 20, n.o 26, 5-35, abril 1964. DOI: https://doi.org/10.32635/2176-9745.RBC.1964v20n26.3746

WOODROFF, M. W.; MURPHY W. T.; HODSON, J. M.: The use of combination of 5 Fu and supervoltage irradiation therapy in advanced carcinoma of urinary bladder: a preliminar report — Cancer Chemoter. Report. 21, aug. 1962.

Published

2023-08-21

How to Cite

1.
Nobre MOR, Cintra RRA. Associação Radioterapia e Quimioterapia. Rev. Bras. Cancerol. [Internet]. 2023 Aug. 21 [cited 2024 Jun. 30];23(33):5-13. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4032

Issue

Section

ORIGINAL ARTICLE