Conceitos Modernos Sobre Obesidade
DOI:
https://doi.org/10.32635/2176-9745.RBC.1967v23n33.4061Keywords:
Obesity/etiology, Obesity/metabolismo, Obesity/prevention & control, Lipogenesis, Lipolysis, Fatty AcidsAbstract
A review was made of the metabolism stressing the study of lipogenesis and lipolysis as wall as the interrelation of fatty acids with glucose in the metabolism energy homeostasis in the light of recently acquired knowledge. The causes of obesity were analysed stressing the genetic predisposition in the biochemical anomalies of the fatty acids and carbohydrates. It was emphasized that the really efficacious treatment must be preventive, taking into account not only the genetic, but the emotional and social factors as well. A scheme was presented for the treatment of severe obesity by intermittent fast.
Downloads
References
ABRAHAM, S. and NORDSIECK, M.; Relationship of excess weight in children and adults. Pub. Health Rep. 75:263, 1960. DOI: https://doi.org/10.2307/4590775
BANSI, H. W. and OLSEN, J. M.: Water retention in obesity. Acta endrocrinol. 32:113, 1959. DOI: https://doi.org/10.1530/acta.0.XXXII0113
BLOOM, W. L. and MITCHELL, W. Jr.: Salt excretion of fasting patients. Arch. Int. Med. 106: 321, 1960. DOI: https://doi.org/10.1001/archinte.1960.03820030009003
BRAGDON, J. H., HAVEL, R. J. and BOYLE, E.: Human serum lipoproteins. J. Lab. & Clin. Med. 48: 36, 1956.
BRUCH, H.: Psychological aspects of obesity. Borden’s Rev. Nutrition Rev. 19: 57, 1958.
COHN, C. and JOSEPH, D.: Effects on metabolism produced by the rate of ingestion of the diet. Am. J. Clin. Nutrition 8: 682, 1960. DOI: https://doi.org/10.1093/ajcn/8.5.682
DOLE, V. P.: A relation between nonesterified fatty acids in plasma and the metabolism of glucose. J. Clin. Invest. 35: 150, 1956. DOI: https://doi.org/10.1172/JCI103259
DUNCAN, G. G., CRISTOFORI, F. C., YUE, J. K. and MURTHY, M. S. J.: The control of obesity by intermittents fasts. M. Clin. North America 48: 1359, 1964. DOI: https://doi.org/10.1016/S0025-7125(16)33406-X
GATES, H, S. and GORDON, R. S.: Demonstration of lipoprotein lipase in human fasting serum. Fed. Proc. 17: 740, 1960.
GORDON, E. S.: Non-esterified fatty acids in the biood of obese and lean subjects. Am. J. Clin. Nutrition 8:740, 1960. DOI: https://doi.org/10.1093/ajcn/8.5.740
GORDON, E. S.: New concepts of the biochemistry and physiology of obesity. M. Clin. North America 48: 1285, 1964. DOI: https://doi.org/10.1016/S0025-7125(16)33401-0
GORDON, E. S., GOLDBERG, M., BRANDABUR, J. J., GEE, J. B. L. and RANKIN, J.; Abnormal energy metabolism in obesity. Tr. A. Am. Physicians 75: 118, 1962.
GORDON, R. s.: Unesterified fatty acid in human biood: II. The transport function of unesterified fatty acid. J. Clin. Invest. 36: 810, 1957. DOI: https://doi.org/10.1172/JCI103486
HOLLIFIELD, G. and PARSON, W.: Metabolic adaptations to a stuff and starve program. II. Obesity and the persistence of adaptative changes in adipose tissue and liver occuring in rats limited to a short daily feeding period. J. Clin. Invest. 41: 250, 1962. DOI: https://doi.org/10.1172/JCI104477
LAURELL, S.: Turnover rate of unesterified fatty acids in human plasma. Acta physiol. scandinav. 41: 158, 1957. DOI: https://doi.org/10.1111/j.1748-1716.1957.tb01517.x
MAYER, J.: Genetic, traumatic and environmental factors in the etiology of obesity. Physiol. Rev. 33: 472, 1953. DOI: https://doi.org/10.1152/physrev.1953.33.4.472
MAYER, J.° Physiological and nutritional aspects of obesity. Borden’s Rev. of Nutr. Rev. 19:35, 1958.
MAYER, J.: Obesity: physiological considerations. Am. J. Clin. Nutrition 9: 530, 1961. DOI: https://doi.org/10.1093/ajcn/9.5.530
MAYER, J.: Obesity. Ann. Rev. Med. 14: 111, 1963. DOI: https://doi.org/10.1146/annurev.me.14.020163.000551
MOORE, M. E., STUNKARD, A. and SROLE, L.: Obesity, social class and mental ilness. L. A. M. A. 181: 962, 1962. DOI: https://doi.org/10.1001/jama.1962.03050370030007
OPIE, L. H. and WALFISH, P. G.: Plasma free fatty acid concentration in obesity. New England J. Med. 268: 757, 1963. DOI: https://doi.org/10.1056/NEJM196304042681404
RANDLE, P. J., GARLAND, P. B., BALES, C. N. and LEWSHOLME, E. A.: The glucose fatty acid cicie. Lancet 1: 785, 1963. DOI: https://doi.org/10.1016/S0140-6736(63)91500-9
ROBINSON, D. S. and BARRIS, P. M.: The production of lipolytic activity in hind limb in response to heparin. Quart. J. Exper. Physiol. 44: 80, 1959. DOI: https://doi.org/10.1113/expphysiol.1959.sp001378
RUDMAN, D., BROWN, S. J. and MALKIN, M. F.: Adipokinetic actions of ACTB, TSB, vasopressin, melanophore stimulating hormone, fraction B, epinephrine, and nor-epinephrine in the rabbit, guinea pig, hamster, rat, pig and dog. J. Lipid Research 4: 527, 1963. DOI: https://doi.org/10.1210/endo-72-4-527
TEPPERMAN, J.: Etiologic factors in obesity and leanness. Perspectives in biology and medicine. 1:293, 1958. DOI: https://doi.org/10.1353/pbm.1958.0023
TREBLE, D. H. and MAYER, J.: Glycerol kinase activity in white adipose tissue of obese-hyperglycemic mice. Nature 200: 363, 1959. DOI: https://doi.org/10.1038/200363a0
VAN ITALLIE, T. B. and BERGEN, S. S.: Regulation of blood glucose. Diabetes 9: 286, 1960. DOI: https://doi.org/10.2337/diab.9.4.286
YOUNG, C. M.: The prevention of obesity. M. Clin. North America 48: 1364, 1964. DOI: https://doi.org/10.1016/S0025-7125(16)33403-4
Downloads
Published
How to Cite
Issue
Section
License
Os direitos morais e intelectuais dos artigos pertencem aos respectivos autores, que concedem à RBC o direito de publicação.
This work is licensed under a Creative Commons Attribution 4.0 International License.
