Funcionalidad De Los Individuos Con Enfermedad Oncológica Ingresados En Unidades De Cuidados Intensivos

Autores/as

DOI:

https://doi.org/10.32635/2176-9745.RBC.2024v70n2.4605

Palabras clave:

Estado funcional, Neoplasias/complicaciones, Unidades de Cuidados Intensivos, Ambulación Precoz, Servicios de Fisioterapia

Resumen

Introducción: Las personas con cáncer representan el 20% de los ingresos a unidades de cuidados intensivos. La reducción de la capacidad funcional es el resultado del cáncer y sus tratamientos, y puede empeorar debido a la inmovilización causada en este sector. Objetivo: Analizar la funcionalidad de individuos con cáncer internados en unidades de cuidados intensivos. Método: Estudio de cohorte prospectivo observacional, en el que se evaluaron individuos con cáncer internados en unidades de cuidados intensivos dentro de las 24 horas posteriores al ingreso y al alta de cuando esto ocurrió mediante la escala de Perme. Se recogieron datos sociodemográficos e informaciones clínicas a través de un cuestionario y de registros médicos, respectivamente. Los datos fueron analizados mediante estadística descriptiva e inferencial. Se aplicó la prueba t para muestras pareadas e independientes y la prueba de correlación de Pearson para las variables cuantitativas. Resultados: Se incluyeron 42 pacientes predominantemente masculinos y con una edad promedio de 62,86 años. El principal tipo de tumor fue del sistema gastrointestinal (40,5%). La ventilación mecánica fue indicativa de menor funcionalidad. Había asociaciones significativas entre la duración de la estancia en la unidad de cuidados intensivos y la funcionalidad al ingreso y al alta. Los pacientes con menor funcionalidad al ingreso tuvieron como resultado la muerte. Al comparar los resultados de ingreso y alta, hubo una mejora significativa en el estado funcional. Conclusión: Los individuos con cáncer ingresados en unidades de cuidados intensivos mostraron mejor funcionalidad durante su estancia.

Descargas

Los datos de descargas todavía no están disponibles.

Citas

Pastores SM. Critical care and oncology. Crit Care Clin. 2021;37(1):15-6. doi: https://doi.org/10.1016/j.ccc.2020.10.001

Schellongowski P, Sperr WR, Wohlfarth P, et al. Critically ill patients with cancer: chances and limitations of intensive care medicine: a narrative review. ESMO Open. 2016;1(5):1-18. doi: https://doi.org/10.1136/esmoopen-2015-000018

Martos-Benítez FD, Soto-García A, Gutiérrez-Noyola A. Clinical characteristics and outcomes of cancer patients requiring intensive care unit admission: a prospective study. J Cancer Res Clin Oncol. 2018;144(4):717-23. doi: https://doi.org/10.1007/s00432-018-2581-0

Wigmore TJ, Farquhar-Smith P, Lawson A. Intensive care for the cancer patient: unique clinical and ethical challenges and outcome prediction in the critically ill cancer patient. Best Pract Res Clin Anaesthesiol. 2013;27(4):527-43. doi: https://doi.org/10.1016/j.bpa.2013.10.002

Grusdat NP, Stäuber A, Tolkmitt M, et al. Routine cancer treatments and their impact on physical function, symptoms of cancer-related fatigue, anxiety, and depression. Support Care Cancer. 2022;30(5):3733-44. doi: https://doi.org/10.1007/s00520-021-06787-5

Sassoon CS, Zhu E, Caiozzo VJ. Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med. 2004;170(6):626-32. doi: https://doi.org/10.1164/rccm.200401-042oc

Dantas CM, Silva PF, Siqueira FH, et al. Influência da mobilização precoce na força muscular periférica e respiratória em pacientes críticos. Rev Bras Ter Intensiva. 2012;24(2):173-8. doi: https://doi.org/10.1590/S0103-507X2012000200013

Costa RT, Zampieri FG, Caruso P. Performance status and acute organ dysfunction influence hospital mortality in critically ill patients with cancer and suspected infection: a retrospective cohort analysis. Rev Bras Ter Intensiva. 2021;33(2):298-303. doi: https://doi.org/10.5935/0103-507X.20210038

Zampieri FG, Romano TG, Salluh JI, et al. Trends in clinical profiles, organ support use and outcomes of patients with cancer requiring unplanned ICU admission: a multicenter cohort study. Intensive Care Med. 2021;47(2):170-79. doi: https://doi.org/10.1007/s00134-020-06184-2

Conselho Nacional de Saúde (BR). Resolução n° 466, de 12 de dezembro de 2012. Aprova as diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos. Diário Oficial da União, Brasília, DF. 2013 jun 13; Seção I:59.

Perme C, Nawa RK, Winkelman C. A tool to assess mobility status in critically ill patients: the Perme Intensive Care Unit Mobility Score. Methodist Debakey Cardiovasc J. 2014;10(1):41-9. doi: https://doi.org/10.14797/mdcj-10-1-41

SPSS®: Statistical Package for Social Science (SPSS)[Internet]. Versão 20.0. [Nova York]. International Business Machines Corporation. [acesso 2023 mar 9]. Disponível em: https://www.ibm.com/br-pt/spss?utm_content=SRCWW&p1=Search&p4=43700077515785492&p5=p&gclid=CjwKCAjwgZCoBhBnEiwAz35Rwiltb7s14pOSLocnooMOQh9qAL59IHVc9WP4ixhNTVMjenRp3-aEgxoCubsQAvD_BwE&gclsrc=aw.ds

Mishra P, Singh U, Pandey CM, et al. Application of student’s t-test, analysis of variance, and covariance. Ann Card Anaesth. 2019;22(4):407-11. doi: https://doi.org/10.4103/aca.aca_94_19

Schober P, Boer C, Schwarte LA. Correlation coefficients: appropriate use and interpretation. Anesth Analg. 2018;126(5):1763-8. doi: https://doi.org/10.1213/ANE.0000000000002864

Jemal A, Ward EM, Johnson CJ, et al. Annual report to the nation on the status of cancer, 1975-2014, featuring survival. J Natl Cancer Inst. 2017;109(9):1-22. doi: https://doi.org/10.1093/jnci/djx030

Torres VB, Vassalo J, Silva UV, et al. Outcomes in critically ill patients with cancer-related complications. PLoS One. 2016;11(10):e0164537. doi: https://doi.org/10.1371/journal.pone.0164537

Soares M, Lobo SM, Torelly AP, et al. Desfecho de pacientes com câncer internados em unidades de terapia intensiva brasileiras com lesão renal aguda. Rev Bras Ter Intensiva. 2010;22(3):236-44. doi: https://doi.org/10.1590/S0103-507X2010000300004

Azevedo LC, Park M, Salluh JI, et al. Clinical outcomes of patients requiring ventilatory support in Brazilian intensive care units: a multicenter, prospective, cohort study. Critical Care (Fullerton). 2013;17(2):63-76. doi: https://doi.org/10.1186/cc12594

Romano AM, Gade KE, Nielsen G, et al. Early palliative care reduces end‐of‐Life intensive care unit (ICU) use but not ICU course in patients with advanced cancer. Oncologist. 2017;22(3):318-23. doi: https://doi.org/10.1634/theoncologist.2016-0227

Jeong BH, Na SJ, Lee DS. Readmission and hospital mortality after ICU discharge of critically ill cancer patients. PLoS One. 2019;14(1):211-15. doi: https://doi.org/10.1371/journal.pone.0211240

Zheng B, Reardon PM, Fernando SM, et al. Costs and outcomes of patients admitted to the intensive care unit with cancer. J Intensive Care Med. 2020;36(2):203-10. doi: https://doi.org/10.1177/0885066619899653

Hsu SH, Campbell C, Weeks AK, et al. A pilot survey of ventilated cancer patients’ perspectives and recollections of early mobility in the intensive care unit. Support Care Cancer. 2019;28(2):747-53. doi: https://doi.org/10.1007/s00520-019-04867-1

Fane M, Weeraratna AT. How the ageing microenvironment influences tumour progression. Nat Rev Cancer. 2020;20(2):89-106. doi: https://doi.org/10.1038/s41568-019-0222-9

Nightingale G, Battisti NM, Loh KP, et al. Perspectives on functional status in older adults with cancer: An interprofessional report from the International Society of Geriatric Oncology (SIOG) nursing and allied health interest group and young SIOG. J Geriatr Oncol. 2021;12(4):658-65. doi: https://doi.org/10.1016/j.jgo.2020.10.018

Heo SJ, Kim G, Lee CK, et al. Prediction of short- and long-term survival for advanced cancer patients after ICU admission. Support Care Cancer. 2015;23(6):1647-55. doi: https://doi.org/10.1007/s00520-014-2519-2

Luna ECW, Perme C, Gastaldi AC. Relationship between potential barriers to early mobilization in adult patients during intensive care stay using the Perme ICU Mobility score. Can J Respir Ther. 2021;57(1):148-53. doi: https://doi.org/10.29390/cjrt-2021-018

Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7-33. doi: https://doi.org/10.3322/caac.21708

Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16(10):626-38. doi: https://doi.org/10.1038/nri.2016.90

Haviland K, Tan KS, Schwenk N, et al. Outcomes after long-term mechanical ventilation of cancer patients. BMC Palliat Care. 2020;19(42):1-6. doi: https://doi.org/10.1186/s12904-020-00544-x

Pereira CS, Carvalho AT, Bosco AD, et al. The Perme scale score as a predictor of functional status and complications after discharge from the intensive care unit in patients undergoing liver transplantation. Rev Bras Ter Intensiva. 2019;31(1):57-62. doi: https://doi.org/10.5935/0103-507x.20190016

Timenetsky KT, Serpa Neto A, Lazarin AC, et al. The perme mobility index: a new concept to assess mobility level in patients with coronavirus (COVID-19) infection. PLoS One. 2021;16(4):1-15. doi: https://doi.org/10.1371/journal.pone.0250180

Nawa RK, Serpa Neto A, Lazarin AC, et al. Analysis of mobility level of COVID-19 patients undergoing mechanical ventilation support: a single center, retrospective cohort study. PLoS One. 2022;17(8):1-17. doi: https://doi.org/10.1371/journal.pone.0272373

Cabilan CJ, Hines S. The short-term impact of colorectal cancer treatment on physical activity, functional status and quality of life: a systematic review. JBI Database System Rev Implement Rep. 2017;15(2):517-66. doi: https://doi.org/10.11124/jbisrir-2016003282

Morishima T, Sato A, Nakata K, et al. Barthel Index-based functional status as a prognostic factor in young and middle-aged adults with newly diagnosed gastric, colorectal and lung cancer: a multicentre retrospective cohort study. BMJ Open. 2021;11(4):1-10. doi: https://doi.org/10.1136/bmjopen-2020-046681

Ronning B, Wyller TB, Jordhoy MS, et al. Frailty indicators and functional status in older patients after colorectal cancer surgery. J Geriatr Oncol. 2014;5(1):26-32. doi: https://doi.org/10.1016/j.jgo.2013.08.001

Grimer R, Athanasou N, Gerrand C, et al. UK guidelines for the management of bone sarcomas. Clin Sarcoma Res. 2010;2010(1):1-14. doi: https://doi.org/10.1186/s13569-016-0047-1

Krajewski S, Furtak J, Zawadka-Kunikowska M, et al. Comparison of the functional state and motor skills of patients after cerebral hemisphere, ventricular system, and cerebellopontine angle tumor surgery. Int J Environ Res Public Health. 2022;19(4):2308-22. doi: https://doi.org/10.3390/ijerph19042308

Druml W, Zajic P, Schellongowski P, et al. Association of acute kidney injury receiving kidney replacement therapy with prognosis of critically ill patients with and without cancer: a retrospective study. Crit Care Med. 2021;49(11):1932-42. doi: https://doi.org/10.1097/ccm.ccm.0000000000005102

Lameire N, Van Biesen W, Vanholder R. Acute renal problems in the critically ill cancer patient. Curr Opin Crit Care. 2008;14(6):635-46. doi: https://doi.org/10.1097/mcc.0b013e32830ef70b

AbuSara AK, Nazer LH, Hawari FI. ICU readmission of patients with cancer: incidence, risk factors and mortality. J Crit Care. 2019;51(1):84-7. doi: https://doi.org/10.1016/j.jcrc.2019.02.008

Puthucheary ZA, Rawal J, McPhail M, et al. Acute skeletal muscle wasting in critical illness. JAMA. 2013;310(15):1591-600. doi: https://doi.org/10.1001/jama.2013.278481

Vanhorebeek I, Latronico N, Van den Berghe G. ICU-acquired weakness. Intensive Care Med. 2020;46(4):637-53. doi: https://doi.org/10.1007/s00134-020-05944-4

Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet. 2009;373(9678):1874-82. doi: https://doi.org/10.1016/s0140-6736(09)60658-9

Dubb R, Nydahl P, Hermes C, et al. Barriers and strategies for early mobilization of patients in intensive care units. Ann Am Thorac Soc. 2016;13(5):724-30. doi: https://doi.org/10.1513/annalsats.201509-586cme

Publicado

2024-06-25

Cómo citar

1.
Käfer DC, Matos E de O de, de Cesaro D, Savaris M, Seger CA, Teixeira AC, Jorge MSG. Funcionalidad De Los Individuos Con Enfermedad Oncológica Ingresados En Unidades De Cuidados Intensivos. Rev. Bras. Cancerol. [Internet]. 25 de junio de 2024 [citado 3 de julio de 2024];70(2):e-234605. Disponible en: https://rbc.inca.gov.br/index.php/revista/article/view/4605

Número

Sección

ARTÍCULO ORIGINAL