Giant Cell tumor of the Zygomatic Arch in a Pediatric Patient: Rare Case Report

Autores

  • Jhulia Farinha Maffini Universidade Positivo (UP). Curitiba (PR), Brazil.
  • Maria Eduarda Turczyn De Lucca Universidade Positivo (UP). Curitiba (PR), Brazil.
  • Leonardo Cesar Ferreira Antunes Universidade Positivo (UP). Curitiba (PR), Brazil.
  • Felipe Antonio Torres Mazzo Pontifícia Universidade Católica do Paraná (PUCPR), Escola de Medicina. Curitiba (PR), Brazil.
  • Carlos Eliseu Barcelos Hospital Erasto Gaertner (HEG), Departamento de Neurocirurgia. Curitiba (PR), Brazil.
  • Rodrigo Leite de Moraes Hospital Erasto Gaertner (HEG), Departamento de Neurocirurgia. Curitiba (PR), Brazil.
  • Eduardo Talib Bacchi Jaouhari Hospital Erasto Gaertner (HEG), Departamento de Neurocirurgia. Curitiba (PR), Brazil.
  • Milena Massumi Kozonoe Hospital Erasto Gaertner (HEG), Departamento de Neurocirurgia. Curitiba (PR), Brazil.
  • Rosângela Stadnick Lauth de Almeida Torres Universidade Positivo (UP). Curitiba (PR), Brazil.

DOI:

https://doi.org/10.32635/2176-9745.RBC.2022v68n2.1880

Palavras-chave:

giant cell tumor of bone, cranial fossa, middle, skull neoplasms, case reports

Resumo

Introduction: A giant cell tumor (GCT) is a rare tumor, usually benign, which can be locally aggressive, with an almost unknown incidence in the skull. Case report: Case report of a pediatric patient diagnosed with Ewing’s sarcoma (ES) and later GCT when sought medical care for an increased volume in the zygomatic arch and the right preauricular region. Imaging exams showed an expansive lesion in the zygomatic and squamous portion of the right temporal bone, with an extradural intracranial component in the middle fossa, with no evidence of infiltration. From the anatomopathological view, fusocelullar neoplasia was seen. The CD68 marker was positive and the S100 marker was negative. Tumor resection by microsurgery was performed. The patient remains in follow-up, with imaging exams at neurosurgery and orthopedics, the latest magnetic resonances of the skull showing a reduction in the size of the lesion. In addition, the patient did not submit to adjuvant therapy and is currently without complaints. Conclusion: This is an important case due to its rarity and clinical data that contributes for the understanding of the pathologies presented, allowing that, in the future, new studies are able to optimize the treatment, and the prognosis for these patients.

Downloads

Não há dados estatísticos.

Referências

Federman N, Brien EW, Narasimhan V, et al. Giant cell tumor of bone in childhood: clinical aspects and novel therapeutic targets. Pediatr Drugs. 2014;16(1):21-8. doi: https://doi.org/10.1007/s40272-013-0051-3 DOI: https://doi.org/10.1007/s40272-013-0051-3

Roberts DS, Faquin WC, Deschler DG. Giant cell tumors of the temporal bone and infratemporal fossa: a case report and review of the literature. Laryngoscope. 2010;120(Suppl 4):S180. doi: https://doi.org/10.1002/lary.21644 DOI: https://doi.org/10.1002/lary.21644

Roberts DS, Faquin WC, Deschler DG. Temporal bone giant cell tumour: report of a second primary giant cell tumour of the temporal bone and infratemporal fossa. B-ENT [Internet]. 2011 [cited 2021 Apr 20];7(4):301-3. Available from: http://www.b-ent.be/en/temporal-bone-giant-cell-tumour-report-of-a-second-primary-giant-cell-tumour-of-the-temporal-bone-and-infratemporal-fossa-16500

Elder JB, Berry C, Gonzalez-Gomez I, et al. Giant cell tumor of the skull in pediatric patients: report of two cases. J Neurosurg. 2007;107(1 Suppl):69-74. doi: https://doi.org/10.3171/PED-07/07/069 DOI: https://doi.org/10.3171/PED-07/07/069

Hamilton SN, Carlson R, Hasan H, et al. Long-term outcomes and complications in pediatric ewing sarcoma. Am J Clin Oncol. 2017;40(4):423-8. doi: https://doi.org/10.1097/COC.0000000000000176 DOI: https://doi.org/10.1097/COC.0000000000000176

Balamuth NJ, Womer RB. Ewing’s sarcoma. Lancet Oncol. 2010;11(2):184-92. doi: https://doi.org/10.1016/S1470-2045(09)70286-4 DOI: https://doi.org/10.1016/S1470-2045(09)70286-4

Downloads

Publicado

2022-05-06

Como Citar

1.
Maffini JF, De Lucca MET, Antunes LCF, Mazzo FAT, Barcelos CE, Moraes RL de, Jaouhari ETB, Kozonoe MM, Torres RSL de A. Giant Cell tumor of the Zygomatic Arch in a Pediatric Patient: Rare Case Report. Rev. Bras. Cancerol. [Internet]. 6º de maio de 2022 [citado 16º de maio de 2022];68(2):e-091880. Disponível em: https://rbc.inca.gov.br/index.php/revista/article/view/1880

Edição

Seção

RELATO DE CASO

Artigos mais lidos pelo mesmo(s) autor(es)