Estimulação Elétrica Transcutânea, Corrente Interferencial e Fotobiomodulação podem levar à Recorrência do Câncer de Mama em Ratas?

Autores

  • Laura Ferreira de Rezende Centro Universitário das Faculdades Associadas de Ensino (Unifae), Faculdade de Fisioterapia. São João da Boa Vista (SP), Brazil. https://orcid.org/0000-0002-3714-1558
  • Eunice Cristina da Silva Costa Centro Universitário das Faculdades Associadas de Ensino (Unifae), Faculdade de Fisioterapia. São João da Boa Vista (SP), Brazil. https://orcid.org/0000-0001-7405-8000
  • Juliana Lenzi Universidade Estadual de Campinas (Unicamp), Faculdade de Madicina. Campinas (SP), Brazil. https://orcid.org/0000-0002-9454-0440
  • Regiane Luz Carvalho Centro Universitário das Faculdades Associadas de Ensino (Unifae), Faculdade de Fisioterapia. São João da Boa Vista (SP), Brazil. https://orcid.org/0000-0003-2948-8903
  • Vanessa Fonseca Vilas Boas Centro Universitário das Faculdades Associadas de Ensino (Unifae), Faculdade de Fisioterapia. São João da Boa Vista (SP), Brazil. https://orcid.org/0000-0002-0675-4781

DOI:

https://doi.org/10.32635/2176-9745.RBC.2022v68n3.2383

Palavras-chave:

estimulação elétrica nervosa transcutânea, terapia por estimulação elétrica, terapia com luz de baixa intensidade, modalidades de fisioterapia, neoplasias da mama

Resumo

Introdução: Estimulação elétrica nervosa transcutânea (TENS), corrente interferencial (IFC) e fotobiomodulação (PBMT) são usadas no tratamento da dor relacionada ao câncer em adultos. No entanto, ainda existem algumas controvérsias sobre os efeitos dessa terapia nas células tumorais que podem permanecer após o tratamento do câncer. Objetivo: Avaliar o risco de recorrência de câncer de mama em ratos ao usar TENS, IFC ou PBMT. Método: Estudo experimental, randomizado, controlado e transversal. Com 90 dias de idade, 7,12-dimetilbenz(a)antraceno (7,12-DMBA) foi administrado em ratos por gavagem gástrica para induzir câncer mamário. Após 120 dias, as glândulas mamarias das ratas pertencentes ao grupo com câncer mamário foram retiradas. Resultados: Foram estudados 39 ratos-fêmeas Sprague-Dawley: nove ratos sem indução de carcinoma mamário; nove ratos com indução de carcinoma mamário e sem cirurgia; nove ratos com indução de carcinoma mamário com cirurgia e placebo, aplicação de TENS, IFC, PBMT; nove ratos com indução de carcinoma mamário, cirurgia e aplicação de TENS, IFC e PBMT. Conclusão: Este estudo demonstrou que houve recorrência local de tumores em ratos que foram estimulados com TENS ou IFC, no entanto, nenhuma evidencia de recorrência local com PBMT.

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Publicado

2022-07-04

Como Citar

1.
Rezende LF de, da Silva Costa EC, Lenzi J, Carvalho RL, Vilas Boas VF. Estimulação Elétrica Transcutânea, Corrente Interferencial e Fotobiomodulação podem levar à Recorrência do Câncer de Mama em Ratas? . Rev. Bras. Cancerol. [Internet]. 4º de julho de 2022 [citado 8º de agosto de 2022];68(3):e-022383. Disponível em: https://rbc.inca.gov.br/index.php/revista/article/view/2383

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