Estudo preliminar do estado atual das pacientes submetidas ao tratamento conservador do câncer de mama do Centro de Ginecologia Luiza Gomes de Lemos - CGLGL – INCa
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https://doi.org/10.32635/2176-9745.RBC.1994v40n4.3004Palavras-chave:
Câncer Inicial de Mama, Cirurgia ConservadoraResumo
Com o objetivo de avaliar o estado atual das pacientes submetidas ao tratamento conservador do câncer inicial de mama no CGLGL, foi realizado um estudo retrospectivo do período de 1983 a 1991. De um total de 192 casos levantados, 140 foram considerados adequados para a avaliação da sobrevida global e sobrevida livre de doença local e a distância. Foram analisados o tamanho tumoral, o tipo histológico, o status menopausal, o comprometimento axilar e o tratamento adjacente, entre outros fatores. Os resultados de sobrevida global (93%), sobrevida livre de doença local (91%) e a distância (89%) em cinco anos, comparam-se àqueles descritos na literatura. Foram considerados fatores clínicos determinantes do prognóstico o grau de comprometimento axilar, o tamanho tumoral e os tumores classificados histologicamente como medulares.
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Referências
Mendonça GAS. Câncer no Brasil: Um risco crescente. Rev bras Cancerol 1992; 38(4): 167-176. DOI: https://doi.org/10.32635/2176-9745.RBC.1992v38n4.3095
Veronesi M, Saccozzi R, Del Vecchio M et al. Comparing radical mastectomy with quadrantectomy. Axiliary dissection and radiotherapy in patients with small cancers of the breast. N EngI J Med 1981; 305: 6-11. DOI: https://doi.org/10.1056/NEJM198107023050102
SarrazinD, LeM, Roueusse J et al. Conservative treatment versus mastectomy in breast cancer tumors with macroscopic diameter of 20 millimeters or less. The Experience of the Institut Gustave-Roussy. Cancer 1984; 53: 1209-1213. DOI: https://doi.org/10.1002/1097-0142(19840301)53:5<1209::AID-CNCR2820530531>3.0.CO;2-Y
Fisher S, Bauer M, Margolese R et al. Five years results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engi J Med 1985; 312: 665-673. DOI: https://doi.org/10.1056/NEJM198503143121101
Straus K, Dichter A, Lippman N et al. Results of the National Cancer Institute Early Breast Cancer Trial. J NatI Cancer Inst Monogr 1992; 11:27-32.
Blichert-Toft M, Rose C, Andersen JA et al. Danish randomized trial comparing breast conservation therapy with mastectomy: six years of life-table analysis. J NatI Cancer Inst Monogr 1992; 11:19-25.
Tubiana-Hulin M, Le Doussal V, Hacene K, Roueusse J, Brunet M. Sequential Identification of factors predicting distant relapse in breast cancer treated by conservative surgery câncer 1993; 72: 1261-1271. DOI: https://doi.org/10.1002/1097-0142(19930815)72:4<1261::AID-CNCR2820720419>3.0.CO;2-4
Van Dongen JA, Bartelínk H, Fentiman IS et al. Randomized clinical trial to assess the value of breast-conserving therapy in stage I and II Breast Cancer. EORTC 10801 Trial. J NatI Cancer Inst 1992; 11: 15-18.
Veronesi M, Salvador! B, Luini A et al. Conservative treatment of early breast cancer. Long-term resuits of 1,232 cases treated with quadrantectomy, axiliary dissection and radiotherapy. Ann Surg 1990; 211(3): 250-259.
Harris JA, Lippman ME, Veronesi M, Willett W. Breast Cancer. N Engi J Med 1992; 327(6): 390-398. DOI: https://doi.org/10.1056/NEJM199208063270606
Hutter RVF. The role of the pathologist in breast cancer management. Cancer 1990; 66:1363-1372. DOI: https://doi.org/10.1002/1097-0142(19900915)66:14+<1363::AID-CNCR2820661411>3.0.CO;2-4
Lonning PE. Treatment of early breast cancer with conservation of the breast. Acta Oncológica, 1991; 30(7): 779-792. DOI: https://doi.org/10.3109/02841869109091821
Margolese R. Surgical considerations in selecting local therapy. J NatI Inst Monogr 1992; 11: 41 -48.
Treatment of early-stage breast cancer. NIH Consensus Conference. JAMA 1991; 265(3): 391 -395. DOI: https://doi.org/10.1001/jama.265.3.391
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Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.