Estudo preliminar do estado atual das pacientes submetidas ao tratamento conservador do câncer de mama do Centro de Ginecologia Luiza Gomes de Lemos - CGLGL – INCa
DOI:
https://doi.org/10.32635/2176-9745.RBC.1994v40n4.3004Keywords:
Early Breast Cancer, Breast Conserving SurgeryAbstract
The objective of this paper is to evaluate the present status of patients who were submitted to conservative surgical therapy for early breast câncer at CGLGL. A retrospective study was conducted from 1983 to 1991. From a total of 192 patients, 140 were considered adequate for the analysis of overall survival, local and distant disease free survival. The parameters included were: tumor size, histological type, menopausal status, presence of axiliary metastasis and adjuvant therapy. The results after a five years follow-up survival - 93%, local disease-free survival -91% and distant disease-free survival - 89%> all of them quite similar to the literature. The prognostic factors ofstatistical value were the number of axiliary lymph node metastases, tumor size and tumors classified histologically as medullary.
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Mendonça GAS. Câncer no Brasil: Um risco crescente. Rev bras Cancerol 1992; 38(4): 167-176. DOI: https://doi.org/10.32635/2176-9745.RBC.1992v38n4.3095
Veronesi M, Saccozzi R, Del Vecchio M et al. Comparing radical mastectomy with quadrantectomy. Axiliary dissection and radiotherapy in patients with small cancers of the breast. N EngI J Med 1981; 305: 6-11. DOI: https://doi.org/10.1056/NEJM198107023050102
SarrazinD, LeM, Roueusse J et al. Conservative treatment versus mastectomy in breast cancer tumors with macroscopic diameter of 20 millimeters or less. The Experience of the Institut Gustave-Roussy. Cancer 1984; 53: 1209-1213. DOI: https://doi.org/10.1002/1097-0142(19840301)53:5<1209::AID-CNCR2820530531>3.0.CO;2-Y
Fisher S, Bauer M, Margolese R et al. Five years results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engi J Med 1985; 312: 665-673. DOI: https://doi.org/10.1056/NEJM198503143121101
Straus K, Dichter A, Lippman N et al. Results of the National Cancer Institute Early Breast Cancer Trial. J NatI Cancer Inst Monogr 1992; 11:27-32.
Blichert-Toft M, Rose C, Andersen JA et al. Danish randomized trial comparing breast conservation therapy with mastectomy: six years of life-table analysis. J NatI Cancer Inst Monogr 1992; 11:19-25.
Tubiana-Hulin M, Le Doussal V, Hacene K, Roueusse J, Brunet M. Sequential Identification of factors predicting distant relapse in breast cancer treated by conservative surgery câncer 1993; 72: 1261-1271. DOI: https://doi.org/10.1002/1097-0142(19930815)72:4<1261::AID-CNCR2820720419>3.0.CO;2-4
Van Dongen JA, Bartelínk H, Fentiman IS et al. Randomized clinical trial to assess the value of breast-conserving therapy in stage I and II Breast Cancer. EORTC 10801 Trial. J NatI Cancer Inst 1992; 11: 15-18.
Veronesi M, Salvador! B, Luini A et al. Conservative treatment of early breast cancer. Long-term resuits of 1,232 cases treated with quadrantectomy, axiliary dissection and radiotherapy. Ann Surg 1990; 211(3): 250-259.
Harris JA, Lippman ME, Veronesi M, Willett W. Breast Cancer. N Engi J Med 1992; 327(6): 390-398. DOI: https://doi.org/10.1056/NEJM199208063270606
Hutter RVF. The role of the pathologist in breast cancer management. Cancer 1990; 66:1363-1372. DOI: https://doi.org/10.1002/1097-0142(19900915)66:14+<1363::AID-CNCR2820661411>3.0.CO;2-4
Lonning PE. Treatment of early breast cancer with conservation of the breast. Acta Oncológica, 1991; 30(7): 779-792. DOI: https://doi.org/10.3109/02841869109091821
Margolese R. Surgical considerations in selecting local therapy. J NatI Inst Monogr 1992; 11: 41 -48.
Treatment of early-stage breast cancer. NIH Consensus Conference. JAMA 1991; 265(3): 391 -395. DOI: https://doi.org/10.1001/jama.265.3.391