Aspectos dos quadros clínico, citológico e da microbiota fúngica da mucosa bucal de pacientes com carcinoma da boca, antes e durante a radioterapia
DOI:
https://doi.org/10.32635/2176-9745.RBC.1990v36n1/4.3116Palavras-chave:
Câncer Bucal, Leveduras, Radiomucosite, Citologia Esfolfativa, C. AlbicansResumo
Os autores estudaram clinicamente as lesões e alterações observadas na mucosa bucal de pacientes com carcinoma da boca, independente da neoplasia presente, antes e durante o tratamento radioterápico, por meio da citologia esfoliativa (Papanicolaou e PAS) e esfregaços corados pelo Gram. Comprovou-se um aumento de leveduras durante o tratamento, predominando as formas filamentosas, consideradas mais patogênicas. Podem-se detectar áreas bem definidas de candidose, quer do tipo atrófica ou pseudomembranosa, além de áreas de radiomucosite, embora a associação de lesões brancas e eritematosas predominassem levando a um mascaramento do quadro clínico presente. Aumento significativo de sintomas desde ardor a xerostomia, entre outros, foi observado durante o tratamento.
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