Um Estudo Experimental Sôbre a Dinâmica da Regeneração Hepática

Autores

  • J. P. Guimarães Laboratório de Patologia Experimental. Seção de Pesquisas. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1964v20n27.3743

Palavras-chave:

Regeneração Hepática, Regeneração Hepática/fisiologia, Intoxicação

Resumo

O Autor desenvolve considerações iniciais sôbre a arquitetura hepática segundo os pontos de vista sustentados por Rappaport, acentuando também a existência de diferenças funcionais entre as duas zonas do acino hepático. Para demonstrar a validade dessas proposições estudou-se a intoxicação tioacetamídica nos seus aspectos morfológicos e dinâmicos. O autor também estuda e discute a influência do equilíbrio endócrino sôbre a regeneração bepática, concluindo por propor uma hipótese de trabalho, segundo a qual o estímulo desencadeador da regeneração hepática seria um excesso relativo de hormônios e metabolitos circulantes, que se seguiria a uma hepatectomia parcial ou a destruição do parênquima hepático.

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2023-09-01

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Guimarães JP. Um Estudo Experimental Sôbre a Dinâmica da Regeneração Hepática. Rev. Bras. Cancerol. [Internet]. 1º de setembro de 2023 [citado 8º de dezembro de 2024];20(27):65-99. Disponível em: https://rbc.inca.gov.br/index.php/revista/article/view/3743

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