Capacidade Funcional e Estado Nutricional em Indivíduos com Mieloma Múltiplo Elegíveis ao Transplante de Células-Tronco Hematopoiéticas: Estudo Observacional
DOI:
https://doi.org/10.32635/2176-9745.RBC.2025v71n4.5242Palavras-chave:
Mieloma Múltiplo, Transplante de Medula Óssea, Teste de Caminhada, Estado NutricionalResumo
Introdução: O transplante de células-tronco hematopoiéticas (TCTH) é uma modalidade de tratamento para mieloma múltiplo (MM). Esse procedimento exige período de isolamento protetor e causa inúmeros efeitos adversos, afetando o estado nutricional e a capacidade funcional, essa associação tende a piorar o prognóstico do paciente. Objetivo: Analisar e correlacionar a capacidade funcional, o estado nutricional e o risco de queda em pacientes com mieloma múltiplo submetidos ao TCTH autólogo. Método: Estudo observacional analítico composto por pacientes de ambos os sexos com diagnóstico de MM. A capacidade funcional foi avaliada pelo teste de caminhada de 6 minutos (TC6) e pela força de preensão manual, o estado nutricional foi verificado pelo índice de massa corporal e pela circunferência braquial, já o risco de quedas foi avaliado pelo teste Timed Up and Go (TUG). Dados foram expressos pela média, desvio-padrão e intervalo de confiança, as correlações foram feitas pelo coeficiente de Pearson. Resultados: A amostra foi composta por 54 pacientes, 44,4% tinham algum grau de obesidade, 85,1% não alcançaram a distância predita no TC6, e não foi identificado risco de queda. A força de preensão manual direita apresentou correlação moderada e positiva com a distância percorrida no TC6 |0,49| (p=0,0001), mas não se correlacionou com a circunferência braquial. O TUG e o TC6 apresentaram correlação negativa e moderada |-0,51| (p=0,0001). Conclusão: A amostra apresentou baixa capacidade funcional. A força de preensão manual se correlacionou com o TC6, porém, não com a circunferência braquial, já o TUG também apresentou correlação com o TC6.
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