Testicular germ cell tumor mimicking pancreatic cancer

Abstract

In the last two decades, germ cell tumors (gonadal or extragonadal) have become the model of a curable solid tumor, especially because of their good sensitivity to cisplatinum-based chemotherapy. Some 90% of cases present testicular symptoms, and the remaining cases those from metastases. This study presents an atypical case that initially appeared to be pancreatic cancer, thus delaying diagnosis. The importance of considering germ cell tumors should be emphasized, mainly in young men with obstructive jaundice and a pancreatic mass, since retroperitoneal metastatic lymph nodes can simulate pancreatic tumor both clinically and radiographically. Most cases are potentially curable but grow rapidly, so late diagnosis can hinder treatment of patients under inadequate conditions.