Effect of a Physical Exercise Program on Acute and Chronic Blood Pressure in Breast Cancer Survivors
DOI:
https://doi.org/10.32635/2176-9745.RBC.2022v68n2.2188Keywords:
cancer survivors, arterial pressure, exerciseAbstract
Introduction: Few studies have explored the outcome of hemodynamic components in cancer survivors in physical exercise programs. Objective: The main objective of this study was to verify acute and chronic changes in systolic (SBP) and diastolic (DBP) blood pressure during an exercise program for breast cancer survivors. Method: In a referral hospital, 24 surviving women participated in a physical exercise program. The BP was monitored with a digital wrist monitor, before and after the sessions. For pre and post-exercise comparison in each session, the t test for paired samples was used. For analysis of chronic effects, analysis of variance (ANOVA) was used, with repeated measures to identify possible differences in pre-exercise variables SBP and DBP throughout the 15 sessions. The level of significance was 5%. Results: It was noticed that, with the exception of the fourth and sixth sessions, the SBP levels decreased in all sessions after exercise (p≤0.05). For DBP, there was only a significant decrease after exercise in the first three sessions. For chronic effects, there was an average reduction in the values of SBP at rest throughout the sessions, with a hypotensive effect above 70% from the seventh session (p≤0.05). In DBP, differences in SBP values at rest were accentuated after the tenth session; when comparing with the values of DBP at rest, a hypotensive effect above 94% was observed. Conclusion: Survivors who adhered to the physical exercise program showed acute and chronic reduction in SBP and DBP.
Downloads
References
Hajjar LA, Costa IBSS, Lopes MACQ, et al. Diretriz Brasileira de Cardio-Oncologia - 2020. Arq Bras Cardiol. 2020;115(5):1006-43. doi: https://doi.org/10.36660/abc.20201006 DOI: https://doi.org/10.36660/abc.20201006
Didier KD, Ederer AK, Reiter LK, et al. Altered blood flow response to small muscle mass exercise in cancer survivors treated with adjuvant therapy. J Am Heart Assoc. 2017;6(2):e004784. doi: https://doi.org/10.1161/JAHA.116.004784 DOI: https://doi.org/10.1161/JAHA.116.004784
Perez IE, Taveras Alam S, Hernandez GA, et al. Cancer therapy-related cardiac dysfunction: an overview for the clinician. Clin Med Insights Cardiol. 2019;13:1179546819866445. https://doi.org/10.1177/1179546819866445 DOI: https://doi.org/10.1177/1179546819866445
Daher IN, Daigle TR, Bhatia N, et al. The prevention of cardiovascular disease in cancer survivors. Tex Heart Inst J. 2012;39(2):190-8. Cited in: PubMed; PMID 22740730.
Cameron AC, Touyz RM, Lang NN. Vascular complications of cancer chemotherapy. Can J Cardiol. 2016;32(7):852-62. doi: https://doi.org/10.1016/j.cjca.2015.12.023 DOI: https://doi.org/10.1016/j.cjca.2015.12.023
Souza VB, Silva EN, Ribeiro ML, et al. Hypertension in patients with cancer. Arq Bras Cardiol. 2015;104(3):246-52. doi: https://doi.org/10.5935/abc.20150011 DOI: https://doi.org/10.5935/abc.20150011
Martins WA, Moço ET. Cardio-oncologia: o preço do envelhecimento. Rev Bras Cardiol. 2012;25(3):164-6.
Pedersen BK, Saltin B. Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases. Scand J Med Sci Sports. 2015;25(Suppl 3):1-72. doi: https://doi.org/10.1111/sms.12581 DOI: https://doi.org/10.1111/sms.12581
Reia TA, Silva RF, Jacomini AM, et al. Acute physical exercise and hypertension in the elderly: a systematic review. Rev Bras Med Esporte. 2020;26(4):347-53. doi: https://doi.org/10.1590/1517-869220202604219195 DOI: https://doi.org/10.1590/1517-869220202604219195
Pescatello LS, Buchner DM, Jakicic JM, et al. Physical activity to prevent and treat hypertension: a systematic review. Med Sci Sports Exerc. 2019;51(6):1314-23. doi: https://doi.org/10.1249/MSS.0000000000001943 DOI: https://doi.org/10.1249/MSS.0000000000001943
Ferioli M, Zauli G, Martelli AM, et al. Impact of physical exercise in cancer survivors during and after antineoplastic treatments. Oncotarget. 2018;9(17):14005-14034. doi: https://doi.org/10.18632/oncotarget.24456 DOI: https://doi.org/10.18632/oncotarget.24456
Neil-Sztramko SE, Winters-Stone KM, Bland KA, et al. Updated systematic review of exercise studies in breast cancer survivors: attention to the principles of exercise training. Br J Sports Med. 2019;53(8):504-12. doi: https://doi.org/10.1136/bjsports-2017-098389 DOI: https://doi.org/10.1136/bjsports-2017-098389
Mills RC, Nascimento MGB, Melo GF, et al. Exercise training improves mean arterial pressure in breast cancer survivors. Motriz: Rev Educ Fis. 2014;20(3):325-31. doi: https://doi.org/10.1590/S1980-65742014000300012 DOI: https://doi.org/10.1590/S1980-65742014000300012
Boer RA, Aboumsallem JP, Bracun V, et al. A new classification of cardio-oncology syndromes. Cardiooncology. 2021;7(1):24. doi: https://doi.org/10.1186/s40959-021-00110-1 DOI: https://doi.org/10.1186/s40959-021-00110-1
Borg G. Escalas de Borg para a dor e o esforço percebido. Barueri (SP): Manole; 2000.
Barroso WKS, Rodrigues CIS, Bortolotto LA, et al. Diretrizes Brasileiras de Hipertensão Arterial - 2020. Arq Bras Cardiol. 2021;116(3):516-658. doi: https://doi.org/10.36660/abc.20201238 DOI: https://doi.org/10.36660/abc.20201238
Viecili PRN, Bündchen DC, Richter CM, et al. Curva dose-resposta do exercício em hipertensos: análise do número de sessões para efeito hipotensor. Arq Bras Cardiol. 2009;92(5):393-9. doi: https://doi.org/10.1590/S0066-782X2009000500010 DOI: https://doi.org/10.1590/S0066-782X2009000500010
World Health Organization. WHO guidelines on physical activity and sedentary behaviour. Geneva: WHO; 2020.
Pescatello LS, MacDonald HV, Lamberti L, et al. Exercise for hypertension: a prescription update integrating existing recommendations with emerging research. Curr Hypertens Rep. 2015;17(11):87. doi: https://doi.org/10.1007/s11906-015-0600-y DOI: https://doi.org/10.1007/s11906-015-0600-y
Carvalho MHC, Nigro D, Lemos VS, et al. Hipertensäo arterial: o endotélio e suas múltiplas funções. Rev Bras Hipertens. 2001;8(1):76-88.
Carpio-Rivera E, Moncada-Jiménez J, Salazar-Rojas W, et al. Efeito agudo do exercício sobre a pressão arterial: uma investigação metanalítica. Arq Bras Cardiol. 2016;106(5):422-33. doi: https://doi.org/10.5935/abc.20160064 DOI: https://doi.org/10.5935/abc.20160064
Cohen JB, Geara AS, Hogan JJ, et al. Hypertension in cancer patients and survivors: epidemiology, diagnosis, and management. JACC CardioOncol. 2019;1(2):238-51. doi: https://doi.org/10.1016/j.jaccao.2019.11.009 DOI: https://doi.org/10.1016/j.jaccao.2019.11.009
Elshahat S, Treanor C, Donnelly M. Factors influencing physical activity participation among people living with or beyond cancer: a systematic scoping review. Int J Behav Nutr Phys Act. 2021;18(1):50. doi: https://doi.org/10.1186/s12966-021-01116-9 DOI: https://doi.org/10.1186/s12966-021-01116-9
Campbell KL, Winters-Stone KM, Wiskemann J. Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable. Med Sci Sports Exerc. 2019;51(11):2375-90. doi: https://doi.org/10.1249/MSS.0000000000002116 DOI: https://doi.org/10.1249/MSS.0000000000002116
Fuller JT, Hartland MC, Maloney LT, et al. Therapeutic effects of aerobic and resistance exercises for cancer survivors: a systematic review of meta-analyses of clinical trials. Br J Sports Med. 2018;52(20):1311. doi: https://doi.org/10.1136/bjsports-2017-098285 DOI: https://doi.org/10.1136/bjsports-2017-098285
Pinto SS, Andrade LS, Fonseca ML, et al. Exercício físico remoto e fadiga em sobreviventes do câncer de mama: uma intervenção em tempos da COVID-19. Rev Bras Ativ Fís Saúde. 2020;25:e0152. DOI: https://doi.org/10.12820/rbafs.25e0152
Mello D, Ostolin TLVDP. Post-exercise hypotension in concurrent training: a systematic review. Rev Bras Cineantropom Desempenho Hum. 2020;22:e72211. doi: https://doi.org/10.1590/1980-0037.2020v22e72211 DOI: https://doi.org/10.1590/1980-0037.2020v22e72211
Contractor PW, Gordon TL, Gordon NF. Hipertensão. In: Erhman JK, Gordon PM, Visich PS, et al. Fisiologia do exercício clínico. 3. ed. São Paulo: Phorte; 2017. p. 173-89.
Monteiro AG, Silva SG, Monteiro GA, et al. Efeito do andamento musical sobre a frequência cardíaca em praticantes de ginástica aeróbica com diferentes níveis de aptidão cardiorrespiratória. Rev Bras Ativ Fís Saúde. 1999;4(2):30-38. doi: https://doi.org/10.12820/rbafs.v.4n2p30-38
Lima AHR, Forjaz CLM, Silva GQM, et al. Acute effect of resistance exercise intensity in cardiac autonomic modulation after exercise. Arq Bras Cardiol. 2011;96(6):498-503. doi: https://doi.org/10.1590/s0066-782x2011005000043 DOI: https://doi.org/10.1590/S0066-782X2011005000043
Coelho-Júnior HJ, Irigoyen MC, Aguiar SS, et al. Acute effects of power and resistance exercises on hemodynamic measurements of older women. Clin Interv Aging. 2017;12:1103-14. doi: https://doi.org/10.2147/CIA.S133838 DOI: https://doi.org/10.2147/CIA.S133838
Laterza MC, Rondon MUB, Negrão CE. Efeito anti-hipertensivo do exercício. Rev Bras Hipertens. 2007;14(2):104-11.
Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc. 2013;2(1):e004473. doi: https://doi.org/10.1161/JAHA.112.004473 DOI: https://doi.org/10.1161/JAHA.112.004473
Corso LML, Macdonald HV, Johnson BT, et al. Is concurrent training efficacious antihypertensive therapy? A meta-analysis. Med Sci Sports Exerc. 2016;48(12):2398-2406. doi: https://doi.org/10.1249/MSS.0000000000001056 DOI: https://doi.org/10.1249/MSS.0000000000001056
Rakobowchuk M, McGowan CL, de Groot PC, et al. Effect of whole body resistance training on arterial compliance in young men. Exp Physiol. 2005;90(4):645-51. doi: https://doi.org/10.1113/expphysiol.2004.029504 DOI: https://doi.org/10.1113/expphysiol.2004.029504
Adão R, Keulenaer G, Leite-Moreira A, et al. Cardiotoxicidade associada à terapêutica oncológica: mecanismos fisiopatológicos e estratégias de prevenção. Rev Port Cardiol. 2013;32(5):395-409. doi: https://doi.org/10.1016/j.repc.2012.11.002 DOI: https://doi.org/10.1016/j.repc.2012.11.002
Stout NL, Baima J, Swisher AK, et al. A systematic review of exercise systematic reviews in the cancer literature (2005-2017). PM R. 2017;9(9S2):S347-S384. doi: https://doi.org/10.1016/j.pmrj.2017.07.074 DOI: https://doi.org/10.1016/j.pmrj.2017.07.074
Published
How to Cite
Issue
Section
License
Os direitos morais e intelectuais dos artigos pertencem aos respectivos autores, que concedem à RBC o direito de publicação.
This work is licensed under a Creative Commons Attribution 4.0 International License.
