Tumor de pequenas células intra-abdominal desmoplásico com diferenciação divergente. Relato de caso e revisão da literatura

Authors

  • Emilio Marcelo Pereira Departamento de Patologia. Faculdade de Medicina. Universidade Estadual Paulista (UNESP), Botucatu (SP). Brasil
  • Sueli Aparecida Maeda Departamento de Patologia. Faculdade de Medicina. Universidade Estadual Paulista (UNESP), Botucatu (SP). Brasil
  • Maria Aparecida Domingues Hemocentro de Santa Catarina (HEMOSC), Florianópolis (SC). Brasil
  • Sérgio Pizoni Müller Centro de Pesquisas Oncológicas de Florianópolis (CEPOM), Florianópolis (SC). Brasil
  • Aiulca Almeida Centro de Pesquisas Oncológicas de Florianópolis (CEPOM), Florianópolis (SC). Brasil
  • Júlio Dalri Centro de Pesquisas Oncológicas de Florianópolis (CEPOM), Florianópolis (SC). Brasil
  • Fernando Carlos Schmitt Departamento de Patologia. Faculdade de Medicina. Universidade Estadual Paulista (UNESP), Botucatu (SP). Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1993v39n2.3021

Keywords:

Small Round Cell Tumor, Peritoneum, Immuno-Peroxidase

Abstract

A distinct type of malignant small ceil tumor has been described because of its peculiar intra-abdominal location as well as pelvic involvement. Some authors have designated the tumor as intra-abdominal desmoplastic small cell tumor with divergent differentiation (IADSC). These tumor display a very unique immunohistochemical profile with co-expresion of muscle, epithelial and neuroendocrine markers. The authors we reports a case of IADSC tumor in a 17 years old boy who presented abdominal tumor and all the morphological and immunohistochemical findings described in this entity. A review of literature is presented.

Downloads

Download data is not yet available.

References

GERALD WL, ROSAI J. Desmoplastic small celL tumor with divergent differentiation. Pediatr Pathol 1989; 9: 177-83. DOI: https://doi.org/10.3109/15513818909022347

ORDONEZ NG, ZIRKIN R, BLOOM RE. Malignant small-cell epithelial tumor of the peritoneum co-expressing mesenchimal type intermediate filaments. Am J Surg Pathol 1989; 13(5): 413-21. DOI: https://doi.org/10.1097/00000478-198905000-00009

GERALD WL; MILLER HK, BATTIFORA H, MIETTINEN M, SILVA EG, ROSAI J. Intra-abdominal desmoplastic small round-cell tumor. Am J Surg Pathol 1991; 15(6): 499-513. DOI: https://doi.org/10.1097/00000478-199106000-00001

GONZALEZ-CRUSSI F, CRAWFORD SE, SUN W. Intra-abdominal desmoplastic small celi tumors with divergent differentiation. AmJ Surg Pathol 1990; 14(7): 633-42. DOI: https://doi.org/10.1097/00000478-199007000-00004

OSBORN M, WEBER K. Tumor diagnosis by intermediate filamento typing. A novel tool for surgical pathology. Lab Invest1983; 48:372-94.

VAM MUIJEN GNP, RUITER DJ, WARNAAN SO. Co-expression of intermediate filament polypeptides in human fetal and adult tissues. Lab Invest 1987; 57: 359-69.

CONDRE JM, De MASCAREL A, TROFANI M, DE MASCAREL I, PAGES A. ImmunohistochemicaI study of rhabdomyosarcoma. Unexpected staining with Si 00 protein and cytokeratin. J Pathol 1988; 155: 127-32. DOI: https://doi.org/10.1002/path.1711550209

MIETTINEN M. lmmunoreactivity for cytokeratin and epitelial membrane antigen in leiomyosarcoma. Arch Pathol Lab Med 1988; 112: 637-40.

NORTON AJ, THOMAS JA, ISAACSON PG. Cytokeratin-specific monoclonal antibodies and reactive with tumours of smooth muscle derivation. An imunocytochemical and biochemical study using antibodies to intermediate filament cytoskeletal proteins. Hystopathology 1987; II: 487-99. DOI: https://doi.org/10.1111/j.1365-2559.1987.tb02657.x

BROWN DC, THEAKER JM, BANKS PM, GATTER KC, MASON DV. cytokeratin expression in smooth muscle and smooth muscle tumours. Hystopathology 1987; ii: 477-86. DOI: https://doi.org/10.1111/j.1365-2559.1987.tb02656.x

KANNERSTEIN M, CHURG J. Peritoneal mosothelioma. Hum Pathol 1977; 8:83-94. DOI: https://doi.org/10.1016/S0046-8177(77)80067-1

SAWYER JR, TRVKA AF, LEWIS M. A novel reciprocal chromosone transiocation T (p13; q12) in an intra-abdominal desmoplastic small round-cell tumor. Am J Surg Pathol 1992; 16(4): 411-16. DOI: https://doi.org/10.1097/00000478-199204000-00010

BARNARDO DE, STAVROV M, BOURIE R, BOGOMOLETZWV. Primary carcinoid of the mesentery. Hum Pathol 1984; 15:796-8. DOI: https://doi.org/10.1016/S0046-8177(84)80174-4

Published

2023-06-16

How to Cite

1.
Pereira EM, Maeda SA, Domingues MA, Müller SP, Almeida A, Dalri J, Schmitt FC. Tumor de pequenas células intra-abdominal desmoplásico com diferenciação divergente. Relato de caso e revisão da literatura. Rev. Bras. Cancerol. [Internet]. 2023 Jun. 16 [cited 2024 Jul. 22];39(2):61-3. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/3021

Issue

Section

CASE REPORT

Most read articles by the same author(s)