Catalasemia em tumor de Wilms
DOI:
https://doi.org/10.32635/2176-9745.RBC.1990v36n1/4.3113Keywords:
Wllms' Tumor, Catalase DeficiencyAbstract
Association between catalase deficiency to neoplasms has been studied in the last years; it is specially remarkable in patients with Wilms' tumor, hereditary form, and aniridia. Few comments are made about occurrence on sporadic forms of the tumor. In 1984, Turleau et al. described the first case of Wilms' tumor and catalase deficiency, without aniridia. In the present study, the authors evaluate catalasemia in 13 patients with Wllms' tumor and compare its levels with 22 chlldren from a normal group and 10 determinations on a control group out of chemotherapy. Results show that catalasemia had higher levels in Wilms' tumor group than in normal control group and the highest levels were seen in patients who had finished chemotherapy regimens. Chemotherapy control group had also high catalasemia levels, supposing that enzimatic activity suffer íorm chemotherapy influence or it is associated to a homeostatic situation on the host.
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