Tratamento Cirúrgico dos Tumores Germinativos do Testículo
DOI:
https://doi.org/10.32635/2176-9745.RBC.1987v33n4.3221Keywords:
Testicular Germinative Tumors, OrchiectomyAbstract
In this study the authors present a critical appraisal of the role of surgery in the strategy of management of patients with germ cell testicular cancer. Special interest is directed to treatment of the primary tumor and the importance of surgery after chemotherapy in patients with advanced disease. Furthermore, a critical discussion on the role of retroperitoneal lymphadenectomy in patients with nonseminomatous tumors is presented.
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References
Batata MA, Unal A - The role of radiation threrapy in relation to stage and histology of testicular cancer. Sem Oncol, 1979; 6. 69.
Boderr D, Gibb R - Radiotherapy and testicular neoplasms. Lancet, 1951; 2.1195 DOI: https://doi.org/10.1016/S0140-6736(51)93202-3
Brackem A B, Smitb KO Is semen cryopreservation helpful in testicular cancer? Urology, 1980; 15 581, DOI: https://doi.org/10.1016/0090-4295(80)90371-4
Bredael JJ, Vugnn O, Whitmore Jr WF - Autopsy findings in 154 palients with germ cell tumors of the testis Cancer, 1982; 50: 548. DOI: https://doi.org/10.1002/1097-0142(19820801)50:3<548::AID-CNCR2820500327>3.0.CO;2-2
Caldwell WL, Kademiari MT, Frias Z, Davis TE The management of testicular seminomas, 1979. Cancer, 1980, 45. 1768. DOI: https://doi.org/10.1002/cncr.1980.45.s7.1768
Carrol PR, Whitrrrore WF Jr, Herr HW, Morse MJ, Sogani PC, Batorunas D, Fair WR, Chaganti ASK - Endocrine and exocrine profiles of men with testicular tumors before orchrectomy. J Urol, 1987; 137. 420, DOI: https://doi.org/10.1016/S0022-5347(17)44054-7
Chong C, Logothetis Ci, Von Eschenbach A, Ayaia A, Samuels M - Orchiectomy in advanced germ celi cancer fotowing intensive cbemotherapy: a comparison of systemic to testicular response .1 Urol, 1986; 136 1221. DOI: https://doi.org/10.1016/S0022-5347(17)45290-6
Cooper JF, Leadbetter WF, Chute A -- The thoracoabdominal approach for retroperitoneal gland dissection: its application to testes tumors Surg Gyn obst, 1950; 90: 486
Dean AL Jr, - The treatment of teratoid tumors of the testis with radium and the x-ray. J Urol, 1925, 13: 149 DOI: https://doi.org/10.1016/S0022-5347(17)73557-4
De Brujjn HWA, Sleijfer Dl, Koops HS, Suurmerjer AJH, Marrink J, Ockhuizen T .- Significance of human chorionic gonadotropin, alpha-fetoprotein and pregnancy-specifrc beta-1-glycoprotein in the detection of tumor relapsa and partial remission in 126 patients with nonseminomalous testicular germ cell tumors. Cancer, 1985; 55. 829. DOI: https://doi.org/10.1002/1097-0142(19850215)55:4<829::AID-CNCR2820550420>3.0.CO;2-A
Dorrohue JP - Retroperitoneal lymphadenectomy. Urol Chn North Arrr, 1977; 4. 509. DOI: https://doi.org/10.1016/S0094-0143(21)01182-4
Donohue JP, Einhorn LH, Perez JM - lmproved managemenl ei nonseminomabus testis tumors. Cancer, 1978; 42. 2903. DOI: https://doi.org/10.1002/1097-0142(197812)42:6<2903::AID-CNCR2820420653>3.0.CO;2-K
Donohue JP, Einhorn LH, Williams SD is adjuvart chemolherapy following retroperitoneal lympb node dissection for nonsemlnomatous testis cancer necessary? Urol Clin North Am, 1980; 7: 747. DOI: https://doi.org/10.1016/S0094-0143(21)00165-8
Donohue JP, Maynard 8, Zachary JM - The distributron of nodal rnetashases in the relroperiteneum from ronseminomateus testis cancer. J Urol, 1982, 128. 315 DOI: https://doi.org/10.1016/S0022-5347(17)52904-3
Donohue JP, Roth LM, Zachary JM, Rowland RG, Einhorn LH, Williams SG - Cytoreduchive surgery for rnetastatic testis cancer: tissue analysis of retroperitoneal tumor masses after chemohherapy. J Urol, 1982, 127: 1111. DOI: https://doi.org/10.1016/S0022-5347(17)54256-1
Elnhorn LH, Donohue JP - Cis-diamminedicbloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer. Ann ml Med, 1977, 87: 293. DOI: https://doi.org/10.7326/0003-4819-87-3-293
Elnhorn LH, Williams SD - Chemotherapy of disseminated testicular cancer. A randon prespechive study. Cancer, 1980; 46 1339. DOI: https://doi.org/10.1002/1097-0142(19800915)46:6<1339::AID-CNCR2820460607>3.0.CO;2-J
Silis M, Sikora K - The current managemenl of testicular cancer. Br JUrol, 1987, 59. 2 DOI: https://doi.org/10.1111/j.1464-410X.1987.tb04569.x
Ewing A, Hetherington JW, Jones WG, Williams RE - Surgioal salvage of advanced testicular tumours. Br J Urol, 1987, 59 76. DOI: https://doi.org/10.1111/j.1464-410X.1987.tb04585.x
Fossa SD, Abyholm T, Normann N, Jetne V - Post-hreahment fertility in patients with testicular cancer. Br J Urol, 1986; 58. 315. DOI: https://doi.org/10.1111/j.1464-410X.1986.tb09062.x
Fraley EE, Lange PH, Kennedy BJ Germ-cell testicular cancer in adults (part I). New Engi J Mcd, 1979; 301: 1370. DOI: https://doi.org/10.1056/NEJM197912203012504
Fraley EE, Lange PH, Kennedy BJ - Germ-celi testicular cancer in adults (part Ii). New Engi 3 Med, 1979; 301: 1420. DOI: https://doi.org/10.1056/NEJM197912273012604
Fraley EE, Markland C, Lange PH - Surgical treatment of stage 1 and stage II non-seminomatous testicular cancer in adults. Urol Clin North Am, 1977; 4: 453. DOI: https://doi.org/10.1016/S0094-0143(21)01178-2
Friedman EL, Garnick MB, Stomper PC, Mauch PM, Harrington DP, Richie JP - Therapeutic guidelines and results in advanced seminoma. J Clin Oncol, 1985; 3: 1325. DOI: https://doi.org/10.1200/JCO.1985.3.10.1325
Garnick MB, Ganchos GP, Richie JP - Trealment and surgical staging of testicular and primary extragonadal germ ccli cancer. JAMA, 1983; 250: 1733 DOI: https://doi.org/10.1001/jama.1983.03340130051032
Geiderman WAH, Schraffordt H, Sieijfer DT, Oeslerhuis JW, Marrmnk J, Bruijn HWA, Oidhoff J - Orchidectomy alone in stage I nonseminomatous testicular germ cell tumors. Cancer, 1987; 59: 578. DOI: https://doi.org/10.1002/1097-0142(19870201)59:3<578::AID-CNCR2820590337>3.0.CO;2-J
Goidiner PL, Schweizer O - The hazards of anesthesia and surgery in bieomycin treated palients. Sem Oncol, 1979; 6: 121.
Hendry WF, Goidstraw P, Peckmam MJ - The role of surgery in lhe combined management of metastases from malignant teratomas of leslis. Br J Urol, 19871 59 358, DOI: https://doi.org/10.1111/j.1464-410X.1987.tb04649.x
Hussey DH, Luk KH, Johnson DE - The role of radiation therapy in the treatment of germinal cell tumors of lhe testis older than pure seminoma. Radiology, 1977; 123: 175. DOI: https://doi.org/10.1148/123.1.175
Javadpour N - The value of biologic markers in diagnosis and treatment of testicular cancer. Sem Oncol, 1979; 6: 37,
Javadpour N - Management of seminoma based on tumor markers. Urol Clin North Am, 1980, 7.773. DOI: https://doi.org/10.1016/S0094-0143(21)00168-3
Javadpour N, Young JD ir. Prognoslic factors in nonseminomalous testicular cancer, J Urol 1986, 125. 497. DOI: https://doi.org/10.1016/S0022-5347(17)45705-3
Johnson DE, Lo 8K, Von Eschenbach AC, Swanson DA - Surveilance alone for patients with clinical stage I nonseminomatous germ cell tumors of lhe testis preliminary results. J Urol, 1984; 131: 491. DOI: https://doi.org/10.1016/S0022-5347(17)50461-9
Kedia KR, Markiand C, Fraley EE - Sexual function after high retroperitoneal lymphadenectomy. Urol Chn North Am, 1977; 4: 523. DOI: https://doi.org/10.1016/S0094-0143(21)01183-6
Kennedy CL, Hendry WF, Peckham MJ - The significance of scrotal interference in stage I testicular cancer managed by orchieclomy and surveiiiance. Br J Urol, 1986, 58 705. DOI: https://doi.org/10.1111/j.1464-410X.1986.tb05917.x
Klein FA, Whitmore WF Jr, Sogani PC, Batata M, Fisher H, Herr HW – Inguinal lymph node melaslases from germ cell testicular tumors. J Urol, 1984, 131497. DOI: https://doi.org/10.1016/S0022-5347(17)50465-6
Lindsey CM, Glenn JF - Germinal malignancies of lhe testes' experience, management and prognosis. J Urol, 1976; 116: 59. DOI: https://doi.org/10.1016/S0022-5347(17)58675-9
Loehrer PJ Sr, Hui S, Clark S, Seal M, Einhorn LH, Wifliams SD, Ulbrighl T, Mandelbaum I, Rowland R, Donohue JP - Teratoma fotowing cispiatin based combination chemotherapy for nonseminomatous germ cell tumors: a clinicopathological correlation. J Urol, 19861 135: 1183. DOI: https://doi.org/10.1016/S0022-5347(17)46031-9
Maillis N, Palton JF - Transperiloncal bilateral lymphadenectomyin testes tumors J Urol. 1958,80: 501. DOI: https://doi.org/10.1016/S0022-5347(17)66213-X
Markiand C - Special problems in managing patients with testicular cancer. Urol Cân North Am, 1977; 4:427 DOI: https://doi.org/10.1016/S0094-0143(21)01177-0
Mcssing EM, Love RR, Kvois LK - Lymphoccle after retroperitoneai node dissection for testis tumor. Cancer, 1986; 57: 871. DOI: https://doi.org/10.1002/1097-0142(19860215)57:4<871::AID-CNCR2820570431>3.0.CO;2-C
Moriyama N, Daly ii, Kraling MA, Lin CW, P,roul GR - Vascular invasion as a prognosticator of metastatic disease in nonseminomalouS germ ccli tumors of lhe leslis. Cancer, 1985, 56: 2492 DOI: https://doi.org/10.1002/1097-0142(19851115)56:10<2492::AID-CNCR2820561027>3.0.CO;2-R
Nilman JM, Jager 5, Boer PW, Kremer J, Oldhoff J, Koops HS - The treatment of ejaculation disorders after retroperitoneal lymph node dissection. Cancer, 1982; 50: 2967. DOI: https://doi.org/10.1002/1097-0142(19821215)50:12<2967::AID-CNCR2820501245>3.0.CO;2-Y
Oliver RTD, Hope-Stone HF, Blandy JP - Justification of lhe use of surveiliance in the management of stage I germ cell tumours of the testis Br J Urol, 1983; 55: 760. DOI: https://doi.org/10.1111/j.1464-410X.1983.tb03421.x
Oliver RTD, Blandy JP, Hendry WF, Pryor JP, Williams JP, Hope-Slone HF - Evaluation of radiotherapy andbr surgicopathological staging after chemotherapy in the management of metastatic germ cell tumours. Br J Urol, 1983; 55: 764. DOI: https://doi.org/10.1111/j.1464-410X.1983.tb03422.x
O'Neili TJ, Kardinai CG, Tierney LM - Reversible intersticial pneumonitis associated with low dose bleomycin. Chesl, 1975, 68: 265. DOI: https://doi.org/10.1378/chest.68.2.265
Peckham MJ, Barrell A, Horwich A, Hendry WF - Orchieclomy alone for stage I testicular non-seminoma. Br 3 Urol, 1983; 55: 754. DOI: https://doi.org/10.1111/j.1464-410X.1983.tb03420.x
Peckham MJ, Husband 3 E, Barrett A, Hendry WF - Orchideclomy alone in testicular stage I nonseminomalous germ-cell tumours. LanceI, 1982; 2: 678. DOI: https://doi.org/10.1016/S0140-6736(82)90710-3
Pizzocaro G, Saivioni R, Zanoni F - Unilateral lymphadeneclomy in intraoperative stage I nonseminomalous germinal testis cancer, 3 Urol, 1985, 134. 485. DOI: https://doi.org/10.1016/S0022-5347(17)47252-1
Pizzocaro G, Zanoni F, Milani A, Piva L, Salvioni B, Pasi M, Pilolti 5, Monfordini S - Retroperitoneal lymphadeneclomy and aggressive chemotherapy in non bulky clinical stage E nonseminomalous germinal leslis lumors. Cancer, 1984; 53: 1363. DOI: https://doi.org/10.1002/1097-0142(19840315)53:6<1363::AID-CNCR2820530624>3.0.CO;2-I
Raghavan D, Vogclzsng Ni, Bosi Gi, Nochomovilz LE, Rosai J, Lange PH, Fraley EE, Goldman A, Torkelson i, Kennedy BJ - Tumor classification and size in germ-cell testicular cancer. lnfiuence on the occurrence mclaslases. Cancer, 1982; 50: 1591. DOI: https://doi.org/10.1002/1097-0142(19821015)50:8<1591::AID-CNCR2820500821>3.0.CO;2-5
Ray B, Hadju Si, Whillmore WF Jr - Distribulion of retroperiloneal lymph node metastases in testicular germinal tumors. Cancer, 1974, 33. 340. DOI: https://doi.org/10.1002/1097-0142(197402)33:2<340::AID-CNCR2820330207>3.0.CO;2-Y
Scardino PT, Skinner DG - Germ cdl tumors of lhe testis: improved results in a prospective study using combirred modalily therapy and biochemical tumor markers. Surgery, 1979; 86: 86.
Silverberg E, Lubera J - Cancer slalislics, 1987 Ca A Cancer i, 19871 37: 2. DOI: https://doi.org/10.3322/canjclin.37.1.2
Skinner DG - Considerations for managcmenl of large retroperitoneal tumors: use of lhe modified thoracoabdominal approach. J Urol, 1977; 117: 605. DOI: https://doi.org/10.1016/S0022-5347(17)58552-3
Smith RB - Retroperitoneal lymphadenectomy in the treatment of testicular seminoma. Urol Chn North Am, 1980; 7: 765. DOI: https://doi.org/10.1016/S0094-0143(21)00167-1
Snow 8W, Rowlsnd RG, Donohue JP, Einhorn LH, Wiíhiams SD - Review of delayed orchieclomy in patients with disseminated testis tumors. J Urol, 1983; 129: 522, DOI: https://doi.org/10.1016/S0022-5347(17)52213-2
Srougi M, Munhoz JB, Tomasini OJ, Toiedo WP, Arap 5, Góes GM Tratamento e prognóstico dos tumores germinativos do testículo. Rev Ass Mcd Brasil, 1978: 24 313.
Srougi M, Sirnon SD, Góes GM - Remissão completa em câncer avançado do testículo como emprego do esquema VAB6: experiência com 40 casos. Rev Ass Med Brasil, 1985, 31: 52.
Srougi M, Simon SD, Góes CM - Vinblastine, aclinomycin D, bleomycin, ciclophosphamide and cis-plalinum for advanced germ cell testis tumors. Brazilian experience. J Urol, 1985; 134: 65 DOI: https://doi.org/10.1016/S0022-5347(17)46983-7
Stsubilz Wi, Early KS, Magcss IV, Murphy GP - Surgical treatment of non-seminomatous germinal testes tumors. Cancer, 1973; 32. 1206. DOI: https://doi.org/10.1002/1097-0142(197311)32:5<1206::AID-CNCR2820320529>3.0.CO;2-7
Slcckamp K, Schreiler F, Allwein JE - Alpha-adrenergic drugs in retrograde ejaculalion. Parti! Slerii, 1970, 25' 817. DOI: https://doi.org/10.1016/S0015-0282(16)40638-2
Slutzman RE, McLecd DG - Radialicn therapy: a primary treatment modality for seminoma. Urol Oin North Am, 1980,7' 757. DOI: https://doi.org/10.1016/S0094-0143(21)00166-X
Taylor HG, Teil DT, Soog Si, McLeod DG - Clinical evolution cf cystic teratoma during treatment with combination chemotherapy, Urology, 1986, 28: 218. DOI: https://doi.org/10.1016/0090-4295(86)90046-4
Vugrin D, Friedrrran A, Whitmore WF Jr - Correlation of serum tumor markers in advanced germ cell tumors with response to chemotherapy and surgery. Cancer, 1984; 53: 1140, DOI: https://doi.org/10.1002/1097-0142(19840315)53:6<1440::AID-CNCR2820530637>3.0.CO;2-G
Vugrin D, Whitmore WF - The role of chemotherapy and surgery in lhe treatment of retroperitoneaa metastases in advanced nonsemincmalous testis cancer. Cancer, 1985, 55' 1874. DOI: https://doi.org/10.1002/1097-0142(19850501)55:9<1874::AID-CNCR2820550905>3.0.CO;2-J
Vugrin D, Whitmore Jr. WF, Golbey RB - Vinblastine, aclincmycin, bleomycin, cyclophosphamide and cis-plalinum combination chemotherapy in metastatic testis cancer - A 1-year program. J Urol, 1982; 128. 1205. DOI: https://doi.org/10.1016/S0022-5347(17)53426-6
Wajsman Z, Beckley SA, Pontes JE - Changing concepts in the treatment of advanced seminomatous tumors J Urol, 1983, 129 303. DOI: https://doi.org/10.1016/S0022-5347(17)52066-2
Whitmore WF Jr. - Surgical treatment of clinical stage I nonseminomalcus germ cell tumors of the testis. Cancer Treal Rep, 1982; 66: 5.
Williams RD, Feinbcrg SB, Knighl LC, Fraley EE - Abdominal staging of testicular tumors using ultrasonography and computed tomography. J Urol, 1980,123: 872. DOI: https://doi.org/10.1016/S0022-5347(17)56172-8
