CarcínomaTrabecular da Pele: Apresentação de Dois Casos e Revisão da Bibliografia

Authors

  • Eleni Maria Vianna Brandão Serviço de Anatomia Patológica e Citológica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil
  • Antonio Geraldo do Nascimento Serviço de Anatomia Patológica e Citológica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil
  • Roberto Alfonso Arcuri Serviço de Anatomia Patológica e Citológica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1983v30n1.3484

Keywords:

Carcinoma, Merkel Cell, Skin Neoplasms/therapy

Abstract

Two cases of Merkel cell carcinoma are reported and the English literatura on this subject is reviewed. This neoplasm occurs in elderly patients and is gene rali y localized in the dermis, usually in the head. It is composed of small, round cells arranged in a diffuse fashion or in trabecular pattern, and exibits a variable number of mitoses. The ultrastructural and histogenetic findings of the lesion are discussed. The tumor shows low-grade malignant behavior with tendency to local recurrence and regional lymph node metastases. Surgery, consisting of local radical resection, with regional lymphnode dissection if necessary, seems to be the best treatment. Adjuvant radiotherapy has been used successfully In a few cases.

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References

DE WOLF-PEETERS, C.; MARIEN. K.; MEBIS, I. and DESMENT V. — A cutaneous APUDoma or Merkel cell tumor? A morphologically recognizable tumor with a biological and histological malignant aspect in contrast with its clinical behavior. Cancer 46: 1810-16, 1980. DOI: https://doi.org/10.1002/1097-0142(19801015)46:8<1810::AID-CNCR2820460819>3.0.CO;2-7

SIBLEY, R.K.; ROSAI, I.; FONCAR,E.; DEHNER, L.P. and BOSL, G. — Neuroendocrine (Merkel cell) carcinoma of the skin. A histologic and ultrastructural study of two cases. Am. J. Surg. Pathol

: 211-21, 1980.

SIDHU, G.S. - Merkel cell neoplasms of the skin. In Lymphoproliferative Diseases of the skin. New York, 1982, Springer-Verlag Publisher. DOI: https://doi.org/10.1007/978-3-642-68363-3_30

SILVA, E.G. and MACKAY, B. - Small cell neuroepithelial tumor of the skin. Lab. Invest. 42: 151, 1980.

TANG, C.K. and TOKER, C. - Trabecular carcinoma of the skin. An ultrastructural study. Câncer 42: 2311-21, 1978. DOI: https://doi.org/10.1002/1097-0142(197811)42:5<2311::AID-CNCR2820420531>3.0.CO;2-L

TANG, C.K. and TOKER, C. - Trabecular carcinoma of the skin. Further clinic-pathologic and ultra structural study. Mt Sinai I. Med.

TAXY, J.B. ETTINGER, D.S. and WHARAM, M.D. - Primary small cell carcinoma of the skin Cancer 46: 2308-11, 1980. DOI: https://doi.org/10.1002/1097-0142(19801115)46:10<2308::AID-CNCR2820461030>3.0.CO;2-B

TOKER, C. — Trabecular carcinoma of the skin. Arch. Demartol 105: 107-10, 1972. DOI: https://doi.org/10.1001/archderm.105.1.107

Published

2023-08-09

How to Cite

1.
Brandão EMV, Nascimento AG do, Arcuri RA. CarcínomaTrabecular da Pele: Apresentação de Dois Casos e Revisão da Bibliografia. Rev. Bras. Cancerol. [Internet]. 2023 Aug. 9 [cited 2024 May 17];30(1):41-7. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/3484

Issue

Section

CASE REPORT