Immunologic Aspects of Hodgkin’s Disease

Authors

  • Alan C. Aisenberg Assistant Physician, Massachusetts General Hospital; Assistant Professor of Medicine, Harvard Medical School, Boston, Massachusetts.

DOI:

https://doi.org/10.32635/2176-9745.RBC.1968v24n36.4130

Keywords:

Hodgkin Disease/immunology, Hodgkin Disease/complications, Cancer Care Facilities, Congresses as Topic

Abstract

Apresentações feitas no Simpósio Internacional sobre Doença De Hodgkin, realizado no Instituto Nacional de Câncer no Rio de Janeiro — 16 a 20 de Janeiro de 1967.

Downloads

Download data is not yet available.

References

AISENBERG, A. C. Studies on delayed hypersensitivity in Hodgkin’s disease. J. Clin. Invest. 41: 1964-1970, 1962. DOI: https://doi.org/10.1172/JCI104654

AISENBERG, A. C. — Hodgkin’s disease Prognosis, treatment and etiologic and immunologic considerations. 270: 508-514, 565-570, 617-622, 1964. DOI: https://doi.org/10.1056/NEJM196403192701206

AISENBERG, A. C. — Studies of lymphocyte trausfer reactions in Hodgkm’s disease. J. Clin. Invest. 44: 555-564, 1965. DOI: https://doi.org/10.1172/JCI105168

AISENBERG, A. C. — Manifestations of immunologic unresponsiveness in Hodgkms disease. Blood 25: 1037-1042, 1965. DOI: https://doi.org/10.1182/blood.V25.6.1037.1037

AISENBERG, A. C. — Manifestations of immunologic unresponsiveness in Hodgkin’s disease. Câncer Research 26: 1152-1160, 1966.

AISENBERG, A. C. and LESKOWITZ, S. — Antibody formation in Hodgkin’s disease. New Eng. J. Med. 268: 1269-1292, 1963. DOI: https://doi.org/10.1056/NEJM196306062682304

AISENBERG, A. C. and WILKES, B. — Immunologic status of thymectomized adult rats. J. Immunol. 93: 75-80, 1964. DOI: https://doi.org/10.4049/jimmunol.93.1.75

ARENDS, T., COONRAD, C. V., and RUNDLES, R. W. — Serum proteins in Hodgkin’s disease and malignant lymphoma. Am. J. Med. 16: 833-841, 1954. DOI: https://doi.org/10.1016/0002-9343(54)90448-9

BARR, M. and FAIRLEY, G. H. — Circulating antibodies in reticuloses. Lancet 1: 1305-1310, 1961. DOI: https://doi.org/10.1016/S0140-6736(61)90237-9

BEILBY, J. O. W., CADE, I. S., JELLIFFE, A. M., PARKIN, D. M., and STEWART, J. W. — Prolonged survival of a bone marrow graft resulting in blood-group chimera. Brit. Med. J. 1: 96-99, 1960. DOI: https://doi.org/10.1136/bmj.1.5166.96

BILLINGHAM, R. E., DEFENDÍ, V., SILVERS, W. K., and STEINMULLER, D. — Quantitativo studies on the induction of tolerance of skin hemografts and on runt disease in neonatal rats. J. Nat. Câncer Inst. 28: 365-435, 1962.

BILLINGHAM, R. E., and SILVERS, W. K. — Sensitivity to hemografts of normal tissues and cells. Am. Rev. Microbiol. 17: 531-564, 1963. DOI: https://doi.org/10.1146/annurev.mi.17.100163.002531

CASAZZA, A. R., DUVALL, C. P., and CARBONE, P. P. — Summary of infectious complications occurring in patients with Hodgkin’s disease. Câncer Research 26: 1290-1296, 1966.

CHASE, M. W. — Delayed-type hyper sensitivity and the immunology of Hodgkin’s disease, with a parallel examination of sarcoidosis. Câncer Research 26: 1907-1120, 1966.

COLLINS, V. P., GELLHORN, A., and TRIMBLE, J. R. — The coincidence of cryptococcosis and disease of the reticulo-endothelial systems. Câncer 4: 883-88J, 1951. DOI: https://doi.org/10.1002/1097-0142(195107)4:4<883::AID-CNCR2820040426>3.0.CO;2-G

CONE, L., and UHR, J. W. — Immunological deficiency disorders associated with chronie lymphatic leukemia and multiple myeloma. J. Clin. Invest. 43: 3341-2248, 1964. DOI: https://doi.org/10.1172/JCI105098

COOPER, M. D., PETERSON, R. D. A., GABRIELSEN, A. E., and GOOD, R. A. — Lymphoid malignancy and development, differentiation and function of the lymphoreticular system. Cancer Research 26: 1165-1169, 1966.

DUBIN, I. N. — Poverty of immunological mechanism in patients with Hodgkm’s disease. Ann. Int. Med. 27: 898-913, 1947. DOI: https://doi.org/10.7326/0003-4819-27-6-898

EWING, J. — Neoplastic Disease: A treatise on tumors. Fourth edition. 1160 pp. Philadelphia; Saunders, 1940.

FAIRLEY, G. H., and AKERS, R. J. — Antibodies to blood group A and B substances in reticuloses. Brit. J. Hem. 8: 375, 1962. DOI: https://doi.org/10.1111/j.1365-2141.1962.tb06542.x

GELLER, W. — Study of antibody formation in patients with malignant lymphomas. J. Lab. and Clin. Med. 42: 232-237, 1953.

GENDEL, B. R., ENDE, M., and NORMAN, S. L. — Cryptococcosis — A review with special refecence to apparent association with Hodgkin’s disease. Am. J. Med. 9: 343-355, 1950. DOI: https://doi.org/10.1016/0002-9343(50)90430-X

GITLIN, D., and CRAIG, J. M. — Thymus in agammaglobulinemia. Pediatrics 32: 517-530, 1963. DOI: https://doi.org/10.1542/peds.32.4.517

GITLIN, D., JANEWAY, C. A., ASP, L., and CRAIG, J. M. — Agammaglobulinemia. In Cellular and Humoral Aspects of the Hypersensitive State, H. S. LAWRENCE, ed. NEw York, Hoeber-Harper, 1959; pp. 375-441.

GOOD, R. A., DALMASSO, A. P., MARTINEZ, C-, ARCHER, O. K.. PIERCE, J. C., and PAPERMASTER, B. E. — The role of the thymus in development of immunologic capacity in rabbits and mice. J. Exp. Med. 116: 773-796, 1862. DOI: https://doi.org/10.1084/jem.116.5.773

GOOD, R. A., KELLEY, W. D., ROTSTEIN, J., and VARCO, R. I. — Immunological deficiency diseases. Prog. Allergy 6: 187-319, 1962. DOI: https://doi.org/10.1159/000313803

GOOD, R. A., MARTINEZ, C., and GABRIELSON, A. E. Clinical considerations of the thymus in immunology. In The Thymus in Immunology, R. A. Good and A. E. Gabrielson, eds. New York: Hoeber-Harper, 1964, pp. 3-47.

GOWANS, J. I., and McGREGOR, D. D. — The immunological activity of lymphocytes. Prog. Allergy 9: 1-78, 1965. DOI: https://doi.org/10.1159/000385896

GRAY, J. G., and RUSSEL, P. S. — Donor selection in human organ transplantation. Lancet 2: 863-865, 1963. DOI: https://doi.org/10.1016/S0140-6736(63)92749-1

GREEN, I., INKELAS, M., and ALLEN, L. B. — Hodgkin’s disease — a maternal-to-foetal lymphocyte chimaera? Lancet 1: 30-32, 1960. DOI: https://doi.org/10.1016/S0140-6736(60)92723-9

GROSS, L. — Immunologieal defect in aged populations and its relation to cancer. Cancer 18: 201-204, 1965. DOI: https://doi.org/10.1002/1097-0142(196502)18:2<201::AID-CNCR2820180211>3.0.CO;2-V

HERSH, E. M., and OPPENHEIM, J. Impaired in vitro lymphocyte transformation in Hodgkin’s disease. New Eng. J. Med. 273: 1006-1012, 1965. DOI: https://doi.org/10.1056/NEJM196511042731903

HOFFMAN, G. T., and ROTTINO, A. — Studies of immunologieal reactions of patients with Hodgkin’s disease: antibody reaction to typhoid immunization. Arch.. Int. Med. 88: 872-876, 1950. DOI: https://doi.org/10.1001/archinte.1950.00230180077006

HOLM, G., PERLMANN, P., and JOHANSSON, B. — Impaired phytohemagglutinin-induced cytotoxicity in vitro of lymphocytes from patients with Hodgkin’s disease or chronic lymphocytic leukemia. Information Exchange Group No. 5, No. 273: 1966.

JACKSON, H., Jr., and PARKER, F., Jr. — Hodgkin’s Disease and Allied Disorders. New York, Oxford Press, 1947.

KAPLAN, H. S., and SMITHERS, D. W. — Autoimmunity in man and homologous disease in mice in relation to the malignant lymphomas. Lancet 2: 1-4, 1959. DOI: https://doi.org/10.1016/S0140-6736(59)92106-3

KELLY, W. D., LAMB, D. L., VARCO, R. L., and GOOD, R. A. — An investigation of Hodgkin’s disease with respect to the problem of homotransplantation. Ann. N.Y. Acad. Sci. 87: 187-202, 1960. DOI: https://doi.org/10.1111/j.1749-6632.1960.tb23192.x

KLIGMAN, A. M., EPSTEIN, W. L. — Some factors affecting contact sensitization in man. In Mechanisms of Hypersensitivity, J. H. Shaffer, G. A. LoGrippo, and M. W. Chase, eds. Boston; Little, Brown, 1959, pp. 713-722.

LAMB, D., PILNEY, R., KELLY, W. D., and GOOD, R. A. — A comparativo study of the incidence of anergy in patients with carcinoma, Hodgkin’s disease and other lymphomas. J. Immunol. 89: 555-558, 1962. DOI: https://doi.org/10.4049/jimmunol.89.4.555

LARSON, D. L., and TOMLINSON, L. J. — Quantitativo antibody studies in man. III. Antibody response in leukemia and other malignant lymphomata. J. Clin. Investigation 32: 317-321, 1953. DOI: https://doi.org/10.1172/JCI102741

LEVIN, A. G., CUSTODIO, D. B., MANDEL, E. E., and SOUTHAM, C. M. — Rejection of cancer homotransplants by patients with debilitating non-neoplastic disease. Ann. N.Y. Acad. Sci. 120: 410-423, 1964. DOI: https://doi.org/10.1111/j.1749-6632.1964.tb34740.x

LEVIN, A. G., McDONOUGH, E. F., Jr., MILLER, D. G., and SOUTHAM, C. M. — Delayed hypersensitivity to DNFB in sick and healthy persons. Ann. N.Y. Acad. Sci. 120: 400-409, 1964. DOI: https://doi.org/10.1111/j.1749-6632.1964.tb34739.x

LOUTIT, J. F. — Immunologieal and trophic functions of lymphocytes. Lancet 2: 1106-1108, 1962. DOI: https://doi.org/10.1016/S0140-6736(62)90803-6

MARSHALL, A. H. E., and WOOD, C. — The involvement of the thymus in Hodgkin’s disease. J. Path. Bact. 73: 163-166, 1957. DOI: https://doi.org/10.1002/path.1700730120

McBRIDE, R. A. — Graft-versus-host reaction in lymphoid proliferation. Cancer Research 26: 1135-1151, 1966.

McINTIRE, K. R., -SELL, S., and MILLER, J. F. A. P. — Pathogenesis of post-thymectomy wasting syndrome. Nature 704: 151-155, 1964. DOI: https://doi.org/10.1038/204151a0

McKELVEY, E. M., and FAHEY, J. L. — Immunoglabulin changes in disease: Quantitation on the basis of heavy polypeptide chains, IgG (yG), IgA (yA), and IgM (yM), and light polypeptide chains, type K (I) and type L (II). J. Clin. Invest. 44: 1778-1787, 1965. DOI: https://doi.org/10.1172/JCI105285

MILLER, D. G. — Patterns of immunological deficiency in lymphomas and leukemias. Ann. Int. Med. 57: 703-716, 1962. DOI: https://doi.org/10.7326/0003-4819-57-5-703

MILLER, D. G. LIZARDO, J. G., and SNYDERMAN, R. — Homologous and heterologous skin transplantation in lymphomatous disease. J. Nat. Câncer Inst. 26: 569-579, 1961.

MILLER, J. F. A. P. — Effect of neonatal thymectomy on the immunological responsiveness of the mouse. Proc. Roíj. Soc. (Biol.) 156: 415-428, 1962. DOI: https://doi.org/10.1098/rspb.1962.0048

MILLER, J. F. A. P., DOAK, S. M. A., and CROSS, A. M. — Role of the thymus in recovery of the imune mechanisms in the irradiated adult mouse. Proc. Soc. Exp. Biol. Med. 112: 785-792, 1963. DOI: https://doi.org/10.3181/00379727-112-28170

MILLIAN, S. J., MILLER, D. G., and SCHAEFP'ER, M. — Viral complemente fixing antibody in patients with Hodgkin’s disease, lymphosarcoma, reticulum cell sarcoma and chronic lymphatic leukemia. Câncer 18: 674-678, 1965. DOI: https://doi.org/10.1002/1097-0142(196506)18:6<674::AID-CNCR2820180604>3.0.CO;2-4

MITCHELL, A. G. WHERRY, W. B., EDDY, B., and STEVENSON, F. E. — Studies in immunity — I. Nonspecific factors influencing the reaction of the skin to tuberculin. Am. J. Dis. Child. 36: 720-724, 1928. DOI: https://doi.org/10.1001/archpedi.1928.01920280071005

PARKER, F., Jr., JACKSON, H., Jr., FITZHUGH, G., and SPIES, T. D. — Studies of diseases of lymphoid and myeloid tissues — IV. Skin reactions to human and avian tuberculin. J. Immunol. 22: 277-282, 1932. DOI: https://doi.org/10.4049/jimmunol.22.4.277

PARROTT, D. M. V., and EAST, J. — Role of the thymus in neonatal life. Nature 195: 347, 1962. DOI: https://doi.org/10.1038/195347a0

PATEY, D. H. A contribution on the study of Hodgkin’s disease. Brit. J. Surg. 50: 389-393, 1953. DOI: https://doi.org/10.1002/bjs.18005022207

PETERS, M. V., and MIDDLEMISS, K. C. H. Study of Hodgkin’s disease treated by irradiation. Am. J. Roentgenol. 79: 114-121, 1958. DOI: https://doi.org/10.1016/S0022-5347(17)66242-6

RAZIS, P. V., DIAMOND, H. D., and CRAVER, L. F. — Hodgkin’s disease associated with other malignant humors and certain nonmalignant diseases. Am. J. Med. Sci. 238: 327-335, 1959. DOI: https://doi.org/10.1097/00000441-195909000-00009

ROSENTHAL, S. R. — Significance of tissue lymphocytes in the prognosis of lymphogranulomatosis. Arch. Path. 21: 628-646, 1936.

SAMTER, M. Eosinophils. In Immunological Diseases, M. Samter, H. L. Alexander, D. VV. Talmage, B. Rose, W. B. Sherman, and J. H. Vaughan, eds. Boston, Little, Brown, 1965, pp. 242-245.

SASLAW, S., CARLISLE, H. D., and BOURONCLE, B. — Antibody response in hematologic patients. Proc. Soc. Exp. Biol. Med. 106: 654, 1961. DOI: https://doi.org/10.3181/00379727-106-26432

SCHIER, W. W. — Cutaneous anergy and Hodgkin’s disease. New Eng. J. Med. 250: 353-361, 1954. DOI: https://doi.org/10.1056/NEJM195403042500902

SCHIER, W. W., ROTH, A., OSTROFF, G., and SCHRIFT, M. H. — Hodgkin’s disease and immunity. Am. J. Med. 20: 94-99, 1956. DOI: https://doi.org/10.1016/0002-9343(56)90176-0

SCHWARTZ, R. S., and BELDOTTI, L. — Malignant lymphomas following allogenic disease — transition from an immunological to a neoplastic disorder. Science 149: 1511-1514, 1965. DOI: https://doi.org/10.1126/science.149.3691.1511

SIMONSEN, M. — Graft versus host reaction — Their natural history, and applicbility as tools of research. Prog. Allergy 6: 349-467, 1962. DOI: https://doi.org/10.1159/000391332

SOKAL, J. E. — Immunologic defects in Hodgkin’s disease. Câncer Research 26: 1161-1164, 1966.

SOKAL, J. E., and PRIMIKIRIOS, N. — The delayed skin test response in Hodgkin’s disease and lymphosarcoma — Effect of disease activity. Câncer 14: 597-607, 1961. DOI: https://doi.org/10.1002/1097-0142(199005/06)14:3<597::AID-CNCR2820140321>3.0.CO;2-X

STARR, S., and BERKOVICH, S. — Effect of measles, gamma-globulin-modified measles and vaccine measles on the tuberculin test. New Eng. J. Med. 27: 394-397, 1964.

STEINER, P. E. — Etiology of Hodgkin’s disease. II. Skin reaction to avian and human tuberculin proteins in Hodgkin’s disease. Arch. Intern. Med. 54: 11-17, 1934. DOI: https://doi.org/10.1001/archinte.1934.00160130014002

THOMSON, A. D. The thymic origin of Hodgkin’s disease. Brit. J. Cancer 9: 37-50, 1955. DOI: https://doi.org/10.1038/bjc.1955.4

ULTMANN, J. E., CUNNINGHAM, J. K., and GELLHORN, A. A. — Hodgkin’s disease — The clinical picture. Cancer Research 26: 1047-1060, 1966.

ULTMANN, J. E., FISH, W., OSSERMAN, E., and GELLHORN, A. — The clinical implications of hypogammaglobulinemia in patients with chronic lymphocyte leukemia and lymphocytic lymphosarcoma. Inn. Intern. Med. 51: 501-516, 1959. DOI: https://doi.org/10.7326/0003-4819-51-3-501

WAKSMAN, B. H., ARNASON, B. G., and JANKOVIC, B. D. — Role of the thymus in immune reactions in rats. J. Exp. Med. 116: 159-206, 1962. DOI: https://doi.org/10.1084/jem.116.2.187

WILLIAMS, H. W., DIAMOND, H. D., CR AVER, L. F., and PARSONS, H. — Neurological Complications of Lymphomas and Leukemias. Springfield, 111., Charles C. Thomas, 1959.

WISEMAN, B. K. — The blood pictures in the primary diseases of the lymphatic system. J.A.M.A. 107: 2016-2022, 1936. DOI: https://doi.org/10.1001/jama.1936.02770510006002

ZIMMERMAN, L. E., and RAPPAPORT, H. — Occurrence of cryptococcosis in patients with malignant disease of the reticuloendothelial system. J. Clin. Path. 24: 1050-1072, 1954. DOI: https://doi.org/10.1093/ajcp/24.9.1050

ZOLLINGER, R. M., Jr., LINDEM, M. C., Jr., FILLER, R. M., CORSO, J. M., and WILSON, R. E. — Effect of thymectomy on skin-homograft survival in children. New Eng. J. Med. 270: 707-710, 1964. DOI: https://doi.org/10.1056/NEJM196404022701404

Downloads

Published

2023-08-18

How to Cite

1.
Aisenberg AC. Immunologic Aspects of Hodgkin’s Disease. Rev. Bras. Cancerol. [Internet]. 2023 Aug. 18 [cited 2024 Jul. 3];24(36):23-37. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4130

Issue

Section

LECTURES and COURSES

Most read articles by the same author(s)