Perceptions of Cancer Patients about Oral Nutritional Therapy through Nutritional Supplements during Chemotherapy Treatment

Authors

  • Aline Ribeiro Ferreira Centro Universitário Tabosa De Almeida, Associação Caruaruense de Ensino Superior, Programa Multiprofissional em Atenção ao Câncer e Cuidados Paliativos (Asces-Unita). Caruaru (PE), Brasil. https://orcid.org/0000-0001-5031-2422
  • Maria Heloisa Moura de Oliveira Centro Universitário Tabosa De Almeida, Associação Caruaruense de Ensino Superior, Programa Multiprofissional em Atenção ao Câncer e Cuidados Paliativos (Asces-Unita). Caruaru (PE), Brasil. https://orcid.org/0000-0003-1028-8207
  • Larissa dos Santos Souza Lima Universidade Federal de Pernambuco (UFPE), Programa de Residência Uniprofissional em Nutrição Clínica. Recife (PE), Brasil. https://orcid.org/0000-0003-0961-8299

DOI:

https://doi.org/10.32635/2176-9745.RBC.2024v70n1.4498

Keywords:

Neoplasms/epidemiology, Drug Therapy, Malnutrition/therapy, Nutritional Therapy/instrumentation, Suplementos Dietéticos

Abstract

Introduction: Treatment toxicity is often associated with anorexia and unintentional weight loss. Oral nutritional therapy (ONT) is a type of strategy carried out through oral nutritional supplements with the purpose of complementing nutritional needs, depending on the adherence to therapy, mainly. Objective: To analyze the perception and adherence of cancer patients to ONT and associate them with demographic factors. Method: Qualitative field study with patients diagnosed with any type of cancer, aged between 18 and 59 years, undergoing chemotherapy treatment, at nutritional risk, certified by a nutritional screening instrument and utilizing ONT. A single interview was carried out, mediated by a semi-structured questionnaire. The data were transcribed, classified and analyzed using the method suggested by Laurence Bardin. Results: The results revealed a diversity of responses, but there was a significant tendency to highlight difficulties in using and adherence, as well as emphasizing the importance of ONT. Among difficulties of adherence, financial difficulties were the most mentioned, followed by the sensory characteristics of the supplements and gastrointestinal changes such as nausea, vomiting, dysgeusia and inappetence. Conclusion: The perception of cancer patients about ONT interferes with adherence to therapy, and is influenced by education, guidance received by the prescribing professional, the sensory characteristics of the nutritional supplements used and the importance they attribute to therapy, in addition to socioeconomic conditions.

Downloads

Download data is not yet available.

References

Santos MO, Lima FCS, Martins LFL, et al. Estimativa de incidência de câncer no Brasil, 2023-2025. Rev Bras Cancerol. 2023;69(1):e-213700. doi: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700 DOI: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700

Instituto Nacional do Câncer. ABC do câncer: abordagens básicas para o controle do câncer [Internet]. 6. ed. Rev. Atual. Rio de Janeiro: INCA; 2020. [acesso 2023 nov 9]. Disponível em: https://www.inca.gov.br/sites/ufu.sti.inca.local/files/media/document/livro-abc-6-edicao-2020.pdf

Pavlova NN, Thompson CB. The emerging hallmarks of cancer metabolism. Cell Metab. 2016;23(1):27-47. doi: https://doi.org/10.1016/j.cmet.2015.12.006 DOI: https://doi.org/10.1016/j.cmet.2015.12.006

Dutra IKA, Sagrillo MR. Terapia nutricional para pacientes oncológicos com caquexia. Discip Scient. Saúde. 2014;15(1):155-69. doi: https://doi.org/10.37777/1074

Ezeoke CC, Morley JE. Pathophysiology of anorexia in the cancer cachexia syndrome. J Cachexia Sarcopenia Muscle. 2015;6(4):287-302. doi: https://doi.org/10.1002/jcsm.12059 DOI: https://doi.org/10.1002/jcsm.12059

Colling C, Duval PA, Silveira DH. Pacientes submetidos à quimioterapia: avaliação nutricional prévia. Rev Bras Cancerol. 2012;58(4):611-7.

doi: https://doi.org/10.32635/2176-9745.RBC.2012v58n4.563 DOI: https://doi.org/10.32635/2176-9745.RBC.2012v58n4.563

Reis MIG, Lima MB, Lima FC. Aspectos nutricionais de pacientes com câncer gástrico e suas implicações no desfecho clínico. Revista JRG. 2023;6(12):77-85. doi: https://doi.org/10.5281/zenodo.7570468

Collatuzzo G, Pelucchi C, Negri E, et al. Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project. Int J Cancer. 2021;149(6):1228-38. doi: https://doi.org/10.1002/ijc.33678 DOI: https://doi.org/10.1002/ijc.33678

Faramarzi E, Mahdavi R, Mohammad-Zadeh M, et al. Validation of nutritional risk index method against patient-generated subjective global assessment in screening malnutrition in colorectal cancer patients. Chin J Cancer Res. 2013; 25(5):544-8. doi: https://doi.org/10.3978/j.issn.1000-9604.2013.10.04

Muscaritoli M, Lucia S, Farcomeni A, et al. PreMiO study group. prevalence of malnutrition in patients at first medical oncology visit: the PreMiO study. Oncotarget. 2017;8(45):79884-96. doi: https://doi.org/10.18632/oncotarget.20168 DOI: https://doi.org/10.18632/oncotarget.20168

Horie LM, Barrére APN, Castro MG, et al. Diretriz BRASPEN de terapia nutricional no paciente com câncer. Braspen [Internet]. 2019 [acesso 2024 nov 9];34(Sup1):2-32. Disponível em: https://ninho.inca.gov.br/jspui/handle/123456789/6606

Ozçağlı TG, Stelling J, Stanford J. A study in four European countries to examine the importance of sensory attributes of oral nutritional supplements on preference and likelihood of compliance. Turk J Gastroenterol. 2013;24(3):266-72. DOI: https://doi.org/10.4318/tjg.2013.0646

Conselho Nacional de Saúde (BR). Resolução n° 466, de 12 de dezembro de 2012. Aprova as diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos. Diário Oficial da União, Brasília, DF. 2013 jun 13; Seção I:59.

Kondrup J, Rasmussen HH, Hamberg O, et al. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003;22(3):321-36. DOI: https://doi.org/10.1016/S0261-5614(02)00214-5

Presidência da República (BR). Lei nº 13.709, de 14 de agosto de 2018. Lei Geral de Proteção de Dados Pessoais (LGPD). Diário Oficial da União, Brasília, DF. 2018 ago 14; Seção I.

Caregnato RCA, Mutti R. Pesquisa qualitativa: análise de discurso versus análise de conteúdo. Texto & Contexto - Enferm. 2006;15(4):679-84. doi: https://doi.org/10.1590/S0104-07072006000400017 DOI: https://doi.org/10.1590/S0104-07072006000400017

Mendes RM, Miskulin RGS. A análise de conteúdo como uma metodologia. Cad Pesqui. 2017;47(165):1044-66. doi: https://doi.org/10.1590/198053143988 DOI: https://doi.org/10.1590/198053143988

Patias ND, Von Hohendorff J. Critérios de qualidade para artigos de pesquisa qualitativa. Psicol estud. 2019;24:e43536. doi: https://doi.org/10.4025/psicolestud.v24i0.43536 DOI: https://doi.org/10.4025/psicolestud.v24i0.43536

Trintenaro JC, Paes AP, Ventura AS. Paciente oncológico frente ao conhecimento da doença. Psique [Internet]. 2016[acesso 2023 out 29];1(2):52-68. Disponível em: https://seer.uniacademia.edu.br/index.php/psq/article/view/946/725

Guedes LRA. Avaliação do conhecimento dos pacientes oncológicos sobre seu diagnóstico, tratamento e prognóstico [dissertação na internet]. São José do Rio Preto: Faculdade de Medicina de São José do Rio Preto; 2017. [acesso 2023 out 29]. Disponível em: http://bdtd.famerp.br/handle/tede/463

Lima MFS, Minetto RDC. Conhecimento de pacientes onco-hematológicos em tratamento quimioterápico sobre os cuidados para prevenção de infecções. Com Ciências Saúde. 2014;25(1):35-44.

Liljeberg E, Nydahl M, Lövestam E, et al. 'Between foods and medicines': A qualitative interview study of patient experiences of the meaning and usage of oral nutritional supplements. Appetite. 2022;178:106163. doi: https://doi.org/10.1016/j.appet.2022.106163 DOI: https://doi.org/10.1016/j.appet.2022.106163

Lima MP, Irigaray TQ. Lócus de controle, escolaridade e conhecimento sobre a doença em pacientes oncológicos. Psicol Saúde Doen. 2019;20(3):659-69. doi: http://dx.doi.org/10.15309/19psd200309 DOI: https://doi.org/10.15309/19psd200309

Alonso CS, Soto CM, Alonso GJ, et al. Efectos adversos metabólicos y nutricionales asociados a la terapia biológica del cáncer. Nutr hosp. 2014;29(2): 259-68. doi: https://dx.doi.org/10.3305/nh.2014.29.2.7023

Instituto Nacional de Câncer José Alencar Gomes da Silva. Consenso nacional de nutrição oncológica [Internet]. 2. ed. rev. ampl. atual. Rio de Janeiro: INCA; 2016. v. 2. Disponível em: https://www.inca.gov.br/publicacoes/livros/consenso-nacional-de-nutricao-oncologica

Stratton RJ, Elia M. Encouraging appropriate, evidence-based use of oral nutritional supplements. Proc Nutr Soc. 2010;69(4):477-87. doi: https://doi.org/10.1017/s0029665110001977 DOI: https://doi.org/10.1017/S0029665110001977

Regan E, Feeney EL, Hutchings SC, et al. Exploring how age, medication usage, and dentures effect the sensory perception and liking of oral nutritional supplements in older adults. Food qual prefer. 2021;92:104224. doi: https://doi.org/10.1016/j.foodqual.2021.104224 DOI: https://doi.org/10.1016/j.foodqual.2021.104224

Morato Martínez M, López-Plaza B, Arcos Castellanos L, et al. Evaluación de las características organolépticas de un suplemento nutricional oral diseñado específicamente para el paciente oncológico. Nutr Hosp. 2023;40(2):266-72. doi: https://doi.org/10.20960/nh.04362 DOI: https://doi.org/10.20960/nh.04362

IJpma I, Renken RJ, Ter Horst GJ, et al. The palatability of oral nutritional supplements: before, during, and after chemotherapy. Support Care Cancer. 2016;24(10):4301-8. doi: https://doi.org/10.1007/s00520-016-3263-6 DOI: https://doi.org/10.1007/s00520-016-3263-6

Garófolo A, Alves FR, Rezende MAC. Suplementos orais artesanais desenvolvidos para pacientes com câncer: análise descritiva. Rev Nutr. 2010;23(4):523-33. doi: https://doi.org/10.1590/S1415-52732010000400003 DOI: https://doi.org/10.1590/S1415-52732010000400003

Alves FR, Garófolo A, Maia PS, et al. Suplemento artesanal oral: uma proposta para recuperação nutricional de crianças e adolescentes com câncer. Rev Nutr. 2010;23(5):731-44. doi: https://doi.org/10.1590/S1415-52732010000500004 DOI: https://doi.org/10.1590/S1415-52732010000500004

Delompré T, Guichard E, Briand L, et al. Taste perception of nutrients found in nutritional supplements: a review. Nutrients. 2019;11(9):2050. doi: https://doi.org/10.3390/nu11092050 DOI: https://doi.org/10.3390/nu11092050

Arthur PS. Desenvolvimento de suplementos artesanais, análise e comparação com suplementos industriais para pacientes em estado de caquexia do câncer. Rev Bras Cancerol. 2023;69(2):e-083855. doi: https://doi.org/10.32635/2176-9745.RBC.2023v69n2.3855 DOI: https://doi.org/10.32635/2176-9745.RBC.2023v69n2.3855

Published

2024-04-25

How to Cite

1.
Ferreira AR, Oliveira MHM de, Lima L dos SS. Perceptions of Cancer Patients about Oral Nutritional Therapy through Nutritional Supplements during Chemotherapy Treatment. Rev. Bras. Cancerol. [Internet]. 2024 Apr. 25 [cited 2024 May 20];70(1):e-254498. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4498

Issue

Section

ORIGINAL ARTICLE