The Impact of COVID-19 on the Diagnosis and Treatment of Prostate Cancer in Paraná

Authors

DOI:

https://doi.org/10.32635/2176-9745.RBC.2024v70n3.4688

Keywords:

COVID-19, Prostatic Neoplasms/diagnosis, Neoadjuvant Therapy, Antineoplastic Protocols, Cancer Care Facilities

Abstract

Introduction: The impact of the COVID-19 pandemic on various health areas is undeniable, yet little is known, in numbers, about the effects that the disease and the ensuing isolation had on oncological patients. Objective: To analyze the impact of the pandemic on the diagnosis and treatment of prostate cancer in specialized hospitals in the North and Northwest of Paraná, comparing the pre-pandemic and pandemic periods (years 2019, 2020, and 2021). Method: Cross-sectional, qualitative and quantitative, ex-post-facto study. Men aged 50 to 70 with diagnosis of prostate cancer were selected, and subsequently, a data collection instrument was used to determine if there was a significant difference in the number of diagnoses, health complications, clinical outcomes, and failure in treatment adherence. Data analysis was conducted using Pearson’s chi-squared test and post hoc analysis with p-value correction. Results: It was observed that the pandemic significantly affected the number of consultations, especially in 2020, but there was no detriment regarding other variables. Conclusion: No failure in treatment adherence was found for these patients, which contributed to many positive outcomes in the course of the disease.

Downloads

Download data is not yet available.

References

Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229-63. doi: https://doi.org/10.3322/caac.21834 DOI: https://doi.org/10.3322/caac.21834

Santos MO, Lima FCS, Martins LFL, et al. Estimativa de incidência de câncer no Brasil, 2023-2025. Rev Bras Cancerol. 2023;69(1):e-213700. doi: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700 DOI: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700

National Cancer Institute [Internet]. Washington, DC: NIH; 2024. Understanding Cancer Prognosis, 2024 maio 29. [atualizado 29 maio 2024 acesso 2024 jan 20]; Disponível em: https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis

Zardeto NHC. Câncer de próstata: análise de sobrevida e fatores prognósticos por faixa etária de diagnóstico [Internet]. Santa Catarina: Universidade Federal de Santa Catarina; 2021. [acesso 2023 out 20]. [Vídeo: 5 min]. Disponível em: https://repositorio.ufsc.br/handle/123456789/225667

Instituto Nacional de Câncer José Alencar Gomes da Silva. Detecção precoce do câncer [Internet]. INCA: Rio de Janeiro; 2021. [acesso 2023 out 10] Disponível em: https://www.inca.gov.br/sites/ufu.sti. inca.local/files//media/document/deteccao-precoce-do-cancer_0.pdf

Há três anos, Paraná confirmava os primeiros casos de COVID-19 e iniciava batalha pela saúde [editorial]. Agência Estadual de Notícias. 2023 mar 12. [acesso 2024 jul 13]. Disponível em: https://www.aen.pr.gov.br/Noticia/Ha-tres-anos-Parana-confirmava-os-primeiros-casos-de-Covid-19-e-iniciava-batalha-pela-saude

Secretaria de Saúde (PR) [Internet]. Curitiba: SS-PR: 2024. Primeiros casos de COVID-19 eram confirmados no Paraná há quase um ano, 2021 mar 10. [acesso 2024 jul 13]. Disponível em: https://www.saude.pr.gov.br/Noticia/Primeiros-casos-de-Covid-19-eram-confirmados-no-Parana-ha-quase-um-ano

Justen A. Brasil.io [Internet]. [Sem local]: 2021. COVID-19: coronavirus newsletters and cases by municipality per day. 2020. [acesso 2024 jul 13]. Disponível em: https://brasil.io/covid19/PR/

Kuderer MN, Choueiri KT, Shah PD, et al. COVID-19 and cancer consortium. clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet. 2020;395:1907-18. doi: https://doi.org/10.1016/S0140-6736(20)31187-9 DOI: https://doi.org/10.1016/S0140-6736(20)31187-9

Nascimento CC, Silva PHS, Cirilo SSV, et al. Desafios e recomendações à atenção oncológica durante a pandemia da Covid-19. Rev Bras Cancerol. 2020;66(TemaAtual):e-1241. Disponível em: https://doi.org/10.32635/2176-9745.RBC.2020v66nTemaAtual.1241 DOI: https://doi.org/10.32635/2176-9745.RBC.2020v66nTemaAtual.1241

Ribeiro MC, Correa MF, Migowski A. Efeitos de curto prazo da pandemia de COVID-19 na realização de procedimentos de rastreamento, investigação diagnóstica e tratamento do câncer no Brasil: estudo descritivo, 2019-2020. Epidemiol Serv Saúde. 2022;31(1):e2021405.[acesso 2023 out 20]. Disponível em: https://doi.org/10.1590/S1679-49742022000100010 DOI: https://doi.org/10.1590/s1679-49742022000100010

Portal da Urologia [Internet]. Rio de Janeiro: SBU; 2024. Cirurgia para retirada da próstata por câncer caiu 21,5%no SUS devido à pandemia 2021, 2021 nov 1. [acesso 2023 out 20]. Disponível em: https://portaldaurologia.org.br/publico/novembro-azul/cirurgia-para-retirada-da-prostata-por-cancer-caiu-215-no-sus-devido-a-pandemia/

Sud A, Jones ME, Broggio J, et al. Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic. Ann Oncol. 2020;31(8):1065-74. doi: https://doi.org/10.1016/j.annonc.2020.05.009 DOI: https://doi.org/10.1016/j.annonc.2020.05.009

Araujo SEA, Leal A, Centrone AFY, et al. Impact of COVID-19 pandemic on care of oncological patients: experience of a cancer center in a Latin American pandemic epicenter. Einstein (São Paulo). 2020;19:eAO6282. doi: https://doi.org/10.31744/einstein_journal/2021AO6282 DOI: https://doi.org/10.31744/einstein_journal/2021AO6282

Bonferroni CE. Teoria statistica delle classi e calcolo delle probabilità. 8 ed. Firenze: Istituto Superiore di Scienze Economiche e Commerciali di Firenze; 1936.

R: The R Project for Statistical Computing [Internet]. Version 3.4.3. [Sem Local]: The R foundation. [Sem data] - [atualizado 2019 mar 11; acesso 2017 jul 15]. Disponível em: https://www.R-project.org

Conselho Nacional de Saúde (BR). Resolução n° 466, de 12 de dezembro de 2012. Aprova as diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos. Diário Oficial da União, Brasília, DF. 2013 jun 13; Seção I:59

Brierley JD, Gospodarowicz M, Wittekind Ch, editores. TNM Classification of Malignant Tumours. 8 ed. Chichester, West Sussex, UK: Wiley Blackwell; 2017. DOI: https://doi.org/10.1002/9780471420194.tnmc26.pub3

Gouveia GA, Moraes YF, Lima PR, et al. Impact of COVID-19 on the curative treatment of prostate cancer: a national cross-sectional study. Rep Pract Oncol Radiother. 2022;27(4):659-65. doi https://doi.org/10.5603/rpor.a2022.0070 DOI: https://doi.org/10.5603/RPOR.a2022.0070

Kamecki H, Rawja P, Przewor A, et al. The impact of coronavirus disease 2019 (COVID-19) pandemic on urologic cancer care: did we throw the baby out with the bathwater? Transl Androl Urol. 2023;12(1):1-4. doi: https://doi.org/10.21037%2Ftau-22-796 DOI: https://doi.org/10.21037/tau-22-796

Diamand R, Ploussard G, Roumiguié M, et al. Timing and delay of radical prostatectomy do not lead to adverse oncologic outcomes: results from a large European cohort at the times of COVID-19 pandemic. World J Urol. 2021;39(6):1789-96. doi: https://doi.org/10.1007/s00345-020-03402-w DOI: https://doi.org/10.1007/s00345-020-03402-w

Nossiter J, Morris M, Parry GM, et al. Impact of the COVID-19 pandemic on the diagnosis and treatment of men with prostate cancer. BJU Int. 2022;130(2):262-70. doi: https://doi.org/10.1111/bju.15699 DOI: https://doi.org/10.1111/bju.15699

Published

2024-08-09

How to Cite

1.
Lima LP de, Bizerra IB, Barbanti PCM. The Impact of COVID-19 on the Diagnosis and Treatment of Prostate Cancer in Paraná. Rev. Bras. Cancerol. [Internet]. 2024 Aug. 9 [cited 2024 Nov. 22];70(3):e-154688. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4688

Issue

Section

ORIGINAL ARTICLE