Fatores Prognósticos e Funcionalidade na Síndrome de Compressão Medular Metastática: um Estudo de Coorte

Autores

  • Eduarda Martins de Faria Centro Universitário IBMR. Rio de Janeiro (RJ), Brasil.
  • Bianca Paraiso de Araujo Centro Universitário IBMR. Rio de Janeiro (RJ), Brasil.
  • Patricia Almeida Chelles Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.
  • Alessandra Grasso Giglio Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.
  • Erica Alves Nogueira Fabro Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.
  • Luciana Velasco Bizzo Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.
  • Anke Bergmann Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.
  • Luiz Claudio Santos Thuler Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Universidade Federal do Estado do Rio de Janeiro (Unirio). Rio de Janeiro (RJ), Brasil.
  • Gustavo Telles da Silva Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA). Rio de Janeiro (RJ), Brasil.

DOI:

https://doi.org/10.32635/2176-9745.RBC.2022v68n2.2160

Palavras-chave:

compressão da medula espinal, neoplasias da coluna vertebral, metástase neoplásica, prognóstico

Resumo

Introdução: A síndrome de compressão medular metastática (SCMM) tem grande potencial de perda irreversível da função motora e sensitiva, sendo considerada uma emergência oncológica. Objetivo: Avaliar o prognostico da SCMM e a funcionalidade dos pacientes com tumores sólidos. Método: Estudo de coorte que incluiu pacientes com câncer que desenvolveram SCMM entre janeiro de 2017 e dezembro de 2018. Os dados clínicos e sociodemográficos foram extraídos dos prontuários físicos e eletrônicos. Analise de sobrevida foi realizada pelo método Kaplan-Meier. Resultados: O estudo abrangeu 90 pacientes que apresentaram SCMM. Ao diagnostico da SCMM, 55,5% dos pacientes não conseguiam realizar marcha. Os pacientes com SCMM após câncer de pulmão tiveram 4,1 vezes maior risco de morrer (IC 95%, 1,79-9,41; p=0,001), os pacientes com tumores geniturinários tiveram 1,9 vezes maior risco de morrer (IC 95%, 1,06-3,45; p=0,02) e os pacientes com outros tipos de tumor tiveram 3,1 vezes maior risco de morrer (IC 95%, 1,58-6,24; p=0,001) quando comparados aos pacientes com SCMM após câncer de mama. Conclusão: Destaca-se a relevância clinica deste estudo ao descobrir que o tipo de tumor primário e um fator preditor independente para sobrevida da SCMM. Ao diagnostico da SCMM, mais da metade dos pacientes não realizam marcha.

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Publicado

2022-06-21

Como Citar

1.
Faria EM de, Araujo BP de, Chelles PA, Giglio AG, Fabro EAN, Bizzo LV, Bergmann A, Thuler LCS, Silva GT da. Fatores Prognósticos e Funcionalidade na Síndrome de Compressão Medular Metastática: um Estudo de Coorte . Rev. Bras. Cancerol. [Internet]. 21º de junho de 2022 [citado 28º de junho de 2022];68(2):e-182160. Disponível em: https://rbc.inca.gov.br/index.php/revista/article/view/2160

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