Meigs Syndrome: Case Report

Authors

  • Pedro Hugo Gouveia Azevedo dos Santos Universidade Federal do Ceará (UFC), Hospital Universitário Walter Cantídio. Fortaleza (CE), Brasil. https://orcid.org/0000-0002-1094-5919
  • Paulo Henrique Silva Nunes Universidade Federal do Ceará (UFC), Faculdade de Medicina. Fortaleza (CE), Brasil. https://orcid.org/0000-0002-9591-1012
  • Letícia Raabe Mota de Lima Universidade Federal do Ceará (UFC), Faculdade de Medicina. Fortaleza (CE), Brasil. https://orcid.org/0000-0003-3584-6850
  • Vinicius Quintanilha Gomes Dias Universidade Federal do Ceará (UFC), Faculdade de Medicina. Fortaleza (CE), Brasil. https://orcid.org/0000-0003-0601-7594
  • Mariana Ferreira Matos Universidade do Estado do Rio Grande do Norte (UERN), Faculdade de Ciências da Saúde. Mossoró (RN), Brasil. https://orcid.org/0009-0006-3652-1774
  • Leandro Rodrigo Pereira de Matos Universidade Federal do Ceará (UFC), Faculdade de Medicina. Fortaleza (CE), Brasil. https://orcid.org/0000-0002-1800-1947
  • Robson Caetano Guedes Assunção Universidade Federal do Cariri (UFCA), Faculdade de Medicina. Barbalha (CE), Brasil. https://orcid.org/0000-0002-7514-7926
  • Heládio Feitosa e Castro Neto Universidade Federal do Ceará (UFC), Hospital Universitário Walter Cantídio. Fortaleza (CE), Brasil. https://orcid.org/0000-0001-6455-916X

DOI:

https://doi.org/10.32635/2176-9745.RBC.2023v69n2.3939

Keywords:

Meigs syndrome, fibroma, ascites, pleural effusion, surgical oncology

Abstract

Introduction: Meigs syndrome is a rare clinical condition, defined as the association of pleural effusion, ascites and ovarian fibroma, with resolution of symptoms after tumor resection. Case report: Female patient, 56 years old, with dry cough associated with hyporexia, weight loss and progressive dyspnea for one month. Chest X-ray and later chest tomography showed massive pleural effusion on the right. Thoracocentesis was performed with drainage of 2,500 ml of serous fluid, suggestive of exudate. On examination, a palpable mass was observed in the hypogastrium, with an upper limit in the umbilicus. Imaging exams show solid expansive formation of possible left ovarian origin and presence of ascitic fluid. The patient underwent total hysterectomy with bilateral salpingo-oophorectomy and resection of the pelvic mass. Intraoperatively, frozen section was suggestive of ovarian fibroma. Histopathological of the surgical specimen confirmed ovarian fibroma measuring 13.0 x 12.5 x 7.5 cm and cytopathological examination of the ascitic fluid was negative for neoplastic cells. The patient evolved in good general condition with resolution of the pleural effusion and ascites and continues without recurrence of symptoms. Conclusion: The definitive diagnosis is made by histological confirmation of ovarian fibroma and resolution of symptoms after removal of the tumor. Dyspnea may be the initial symptom and the CA-125 may be elevated. The prognosis is usually good and the chances of recurrence are minimal.

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References

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Published

2023-05-25

How to Cite

1.
Santos PHGA dos, Nunes PHS, Lima LRM de, Dias VQG, Matos MF, Matos LRP de, Assunção RCG, Castro Neto HF e. Meigs Syndrome: Case Report. Rev. Bras. Cancerol. [Internet]. 2023 May 25 [cited 2025 Apr. 1];69(2):e-253939. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/3939

Issue

Vol. 69 No. 2 (2023): Apr./May/June

Section

CASE REPORT

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