Soft Tissue Sarcomas: Treatment Results in Low-grade Tumors

Abstract

Objectives: The objectives were to describe the experience at our hospital's Soft Tissue Department in the treatment of low-grade sarcomas and to analyze factors associated with local recurrence. Methods: Seventy-six patients were analyzed retrospectively. Information was recorded on pain, previous surgery, localization, histopathology, surgical treatment, recurrences, and evolution. Results: Overall 5-year survival was 94%, local failure occurred in 17 patients (22.3%), and 9 (11.8%) presented metastasis. Adjuvant radiotherapy was indicated in 23 patients (30.2%). Factors that influenced local recurrence were tumor size >5cm (OR 12.09; 95%CI 1.73-84.53; p=0.012) and inadequate margins (OR 47.16; 95%CI 3.42-650.33; p=0.004), identified only in the group with limb and superficial trunk sarcomas. Conclusions: The results were consistent with the literature. Tumor size >5cm and inadequate margins were the main factors for local recurrence.