Primary splenic angiosarcoma: case report and literature review

Authors

  • Luís Fernando Venegas Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Paula Ratfin Pohlmann Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Alexsandra Lima Balbinot Universidade Federal do Rio Grande do Sul. Porto Alegre (RS), Brasil.
  • Eduardo Schuck Universidade Federal do Rio Grande do Sul. Porto Alegre (RS), Brasil.
  • Carla T. M. de Oliveira Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Klaus J. Frank Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Carlos F. Dillemburg Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Mário S. B. da Costa Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Luis Fernando R. Rivero Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.
  • Antonio C. K. Pütten Hospital de Clínicas de Porto Alegre (HCPA). Porto Alegre (RS), Brasil.

DOI:

https://doi.org/10.32635/2176-9745.RBC.1998v44n1.2800

Keywords:

Angiosarcoma, Splenic Neoplasms, Chemotherapy, Pathology, Immuno-Histochemistry

Abstract

This paper describes a case of an aggressive primary splenic angiosarcoma in a 29-year-old man and makes a review of its clinicai findings, pathologic reports, treatment and prognosis. Angiosarcomas comprise less than 1% of soft tissue sarcomas, and only a small percentage of these tumors arise in the spleen. These tumors usually represent a diagnostic challenge for the pathologist in view of its variegated histology, and the development of new immu-nohistochemical markers for vascular tumors like CD31 (platelet-endothelial cell adhesion molecule) helps to rule out other diagnoses. There is no standard chemotherapy treatment for angiosarcomas, and the prognosis of splenic angiosarcoma is particularly poor.

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Published

2022-09-27

How to Cite

1.
Venegas LF, Pohlmann PR, Balbinot AL, Schuck E, Oliveira CTM de, Frank KJ, Dillemburg CF, Costa MSB da, Rivero LFR, Pütten ACK. Primary splenic angiosarcoma: case report and literature review. Rev. Bras. Cancerol. [Internet]. 2022 Sep. 27 [cited 2024 Jun. 26];44(1):51-6. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/2800

Issue

Vol. 44 No. 1 (1998): Jan./Feb./Mar.

Section

CASE REPORT

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