Pleurodese em câncer de pulmão Melhora na sobrevida

Authors

  • Sérgio Jamnik Mestre em Pneumologia. Escola Paulista de Medicina (EPM). São Paulo (SP), Brasil
  • llka Lopes Santoro Médica contratada da Disciplina de Pneumologia. Escola Paulista de Medicina (EPM). São Paulo (SP), Brasil
  • Hakaru Tadokoro Doutor em Pneumologia. Chefe do Grupo de Oncologia. Escola Paulista de Medicina (EPM). São Paulo (SP), Brasil
  • Cesar Uehara Professor Adjunto da Disciplina de Pneumologia. Escola Paulista de Medicina (EPM). São Paulo (SP), Brasil
  • Octávio Ribeiro Ratto Professor Titular da Disciplina de Pneumologia. Escola Paulista de Medicina (EPM). São Paulo (SP), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1995v41n3.2941

Keywords:

Pleural Effusion, Lung Cancer, Pleurodesis, Survival

Abstract

We compared two groups (A and B) of patients with lung cancer and pleural effusion. The A group with 21 patients, we performed pleurodesis with tetraciclin or mitomycin, and the B group of 66 patients without pleurodesis. The A group was patients with a rapid relapses of pleural effusion and a possibility of survival of months To not choose good performances status for óne group, we randomized the patients with initial for both groups, that the Mann-Withney test was equal to both. We performed the Kapian-Meyer survival probabilily curve and the test of Cox-Mantei to compare the two groups. The survival was longer for the patients with pleurodesis (p = 0,0 16502).

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References

America Joint Committee for Cancer Staging and End Results Reporting Manual for Staging of Cancer. Chicago American College of Surgeons, 1977, p. 59-61.

ANDERSON, C.B.; PHILPOTT G.W.; FERGUSON, T.B. - The treatment of malignant pleural effusion. Cancer, 88.532-7, 1978.

AUSTIN, EH.; FLYE, M.W. - The treatment of recurrent malignant pleural effusion. Ann Thorac Surg, 28: 190-203, 1979. DOI: https://doi.org/10.1016/S0003-4975(10)63779-4

BETHUME, N. - Pleural poudrage. A new technique for the deliberate production of pleural adhesions as a preliminary to lobectomy. J Thorax Surg, 4251-61, 1935.

BRINKMAN, G.L. - The significance of pleural effusion complicating otherroise operable bronchogenic carcinoma. Dis Chest, 36:152-4, 1959. DOI: https://doi.org/10.1378/chest.36.2.152

DEKKER, A; BUPP, P.A. - Citology of senous effusion: An investigation into the usefulness of cell blocks verus smears. Am Clin Pathol, 70:855-60, 1978. DOI: https://doi.org/10.1093/ajcp/70.6.855

ESTENNE, M; YERNAULT, J.C.; DE TROYER, A. - Mechanisms of relief of dispnea alter thoracentesis in patients with large pleural effusion. Am J Med, 74.813- 819, 1983. DOI: https://doi.org/10.1016/0002-9343(83)91072-0

FRACCHIA, A.A.; KNAPPER, W.H.; CAREY, J.T.; FARROW, J.H. - Intrapleural chemotherapy for effusion from metastatic breast cancer. Cancer, 26:626-9, 1970. DOI: https://doi.org/10.1002/1097-0142(197009)26:3<626::AID-CNCR2820260320>3.0.CO;2-3

FRIEDMAN, M.A.; SLATER, E. - Malignant pleural effusion. Cancer Treat Rev, 5:49-66, 1978. DOI: https://doi.org/10.1016/S0305-7372(78)80006-1

JAMNIK, S. - Derrame pleural em portadores de carcinoma broncogônico. São Paulo, 1993. (Tese - Mestrado - Escola Paulista de Medicina).

JUSTIN-BEDANÇON, L.; BROVET, G.; CHRETIEN, J. - Deux observations hemopneumothorax spontanè revelateur de tumeur maligne de la pleure. J Fr Med Clir Thor, 8.616-32, 1954.

KAPLAN, G.; MEIER, P. - Non parametric estimation from incomplete observations. JAm StatAssoc, 53:457- 81, 1958. DOI: https://doi.org/10.1080/01621459.1958.10501452

LEE, E.T. - Statistical Methods for survival data analysis, Belmont, USA Lifetime Heasning Publication, 1980.

LEFF, A.; HOPERWELL, P.C.; CASTELLO, J. – Pleural effusion from malignancy. Ann lntern Med, 88.532-7, 1978. DOI: https://doi.org/10.7326/0003-4819-88-4-532

LIGHT, R.W. - Malignant pleural effusion – ln the pleural diseases. Philadeiphia, Lea & Febiger, 1983, p. 77-85.

LIGHT, R.W. - Tumours of the pleura. In textbook of Respiratory Medicine. Edited by W.B. Saunders, Phliadelphia, USA, 1988, p. 1770-80.

LORCH, D.G.; GORDON, L.; WOOTEN, S. et al. - The effect of patient positioning on the distribution of tetracycline in the pleural space during pleurodesis. Chest, 98:527-9, 1988. DOI: https://doi.org/10.1378/chest.93.3.527

OSTROWSKI, M.J.; HALSALL, G.M. – lntracavitary bleomycin in the management of malignant effusions: A multicenter study. Cancer Treat Rev, 66:1902-7, 1982.

OSTROWSKI, M.L.; PRIESTMAN, T.J.; HOUSTON, R.F.; MARTIN, W.M.C. - A randomized trial of intracavitary bleomycin and Corynebacterium parvum in the control of malignant pleural effusion. Radiother Oncol, 14.19-26, 1989. DOI: https://doi.org/10.1016/0167-8140(89)90004-2

PALADINE, J.W.; CUNNINGHAM, T.J.; SPONZO, R.; DONOVAN, M.; OLSON, K.; HORTON, J. – lntracavitary bleomycin in the management of malignant effusions. Cancer, 38:1902-8, 1976. DOI: https://doi.org/10.1002/1097-0142(197611)38:5<1903::AID-CNCR2820380506>3.0.CO;2-A

POE, R.H.; ISRAEL, R.H.; UTELL, M.J. et al. - Sensitivity, specificity, and predictive values of closed pleural biopsy. Arch Int Med, 144325, 1984. DOI: https://doi.org/10.1001/archinte.1984.00350140139020

PRYCE, D.M.; WALTER, J.B. - The frequency of gross vascular invasions in lung cancer with special reference to arterial invasion. J Pathol Bacteriol, 79:141-9, 1960. DOI: https://doi.org/10.1002/path.1700790117

RUBSON, R.M.; BALOOKI, H. - Intrapleural tetracicline for control of malignant pleural effusion: a preliminar report. South Med J, 65:847-9, 1972. DOI: https://doi.org/10.1097/00007611-197207000-00016

RUCKDESCHEL, J.C. - Management of malignant pleural effusion. An Ovetview Semin Oncol, 15:24-8, 1988.

SAHN, S.A. - When cancer patients develop pleural effusions. J Respir Dis, 2:53-63, 1981.

SAHN, S.A. - Malignant pleural effusions. Clin Chest Med, 6:113-25, 1985. DOI: https://doi.org/10.1016/S0272-5231(21)00343-9

SAHN, S.A. - Malignant pleural effusions. Semin Respir Med, 9:43-53, 1987. DOI: https://doi.org/10.1055/s-2007-1012687

SAHN, S.A. - The Pleura. Am Rev Respir Dis, 38:184- 234, 1988. DOI: https://doi.org/10.1164/ajrccm/138.1.184

SAHN, S.A. - Malignant pleural effusion In Fishman A.P. - Pulmonary Disorders and Disorders, 2a. ed. New York, Mac Graw - Hill, 1988, 2159-69.

SAHN, S.A.; GOOD, J.T.JR. - The effect of common scierosing agents on the rabbit pleural space. Am Rev Respir Dis, 124:65-7, 1981.

SAHN, S.A.; GOOD, J.TJR.; POTTS, D.E. - The pH of sclerosing agents a determinant of pleural symphysis. Chest, 76:198-200, 1979. DOI: https://doi.org/10.1378/chest.76.2.198

SAHN, S.A.; POTTS, D.E. - The effect of tetracycline on rabb pleura. Am Rev Respir Dis, 117:493-9, 1978.

SARMA, P.R.; MOORE, M.R. - Approach to the management of pleural effusion in malignancy. South Med J, 71:133-6, 1978. DOI: https://doi.org/10.1097/00007611-197802000-00013

SILVERBERG, I. - Management of effusion. Oncology, 24.26-30, 1970. DOI: https://doi.org/10.1159/000224501

SPRINGS, A. I.; BODDINGTON, M.M. - The citology of effusions 2a. ed. Edition New York, Grune e Stratton, 1968.

TADOKORO, H. - Câncer de pulmão: Considerações sobre 300 casos. São Paulo, 1992. (Tese – Doutorado - Escola Paulista de Medicina).

TANDON, R.K. - The significance of pleural effusion associated with bronchial carcinoma. Br J Dis Chest, 60:40-53, 1966. DOI: https://doi.org/10.1016/S0007-0971(66)80023-2

THORSRUD, G.K. - Pleural reactions to irritants: Na experimental study with special reference to pleural adhesions and concrescence in relation to pleural turn-over of fluid. Acta Chir Scand, 355 (supp1):10-74, 1965.

TORREGROSA, M.V. - Results of latic dehydrogenase determinations in benign and malignant effusions. Amer J Med Sci, 238.553-3, 1959. DOI: https://doi.org/10.1097/00000441-195911000-00004

WALLACH, H.W. - Intrapleural tetracycline for malignant effusions. Chest, 68.510-2, 1975. DOI: https://doi.org/10.1378/chest.68.4.510

WALLACH, H.W. - Intrapleural therapy with tetracycline and lidocaine for malignant pleural effusions. Chest, 73246-247, 1978. DOI: https://doi.org/10.1378/chest.73.2.246

ZALOZNIK, A.J.; OSWALD, S.G.; LANGEM, M. - Intrapleural Tetracyciine in malignant pleural effusions. A randomized study Cancer, 5:752-5, 1985. DOI: https://doi.org/10.1002/1097-0142(19830215)51:4<752::AID-CNCR2820510434>3.0.CO;2-7

Published

2022-10-05

How to Cite

1.
Jamnik S, Santoro llka L, Tadokoro H, Uehara C, Ratto OR. Pleurodese em câncer de pulmão Melhora na sobrevida. Rev. Bras. Cancerol. [Internet]. 2022 Oct. 5 [cited 2024 May 19];41(3):153-8. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/2941

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ORIGINAL ARTICLE