Histogênese e patogênese das neoplasias hepáticas
DOI:
https://doi.org/10.32635/2176-9745.RBC.1990v36n1/4.3124Keywords:
Hepatic CaranogenesisAbstract
This is a study on hepatic carcinogenesis followed by a revision of bibliography on the subject.
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WEISBURGEA JH, MADISON RM, WARD JM, VIGUERA C, WE1SBURGER EK. Modification of diethyinitrosamine liver carcinogenesis with phenobarbital but not with immunosuppression. JNCi 1975; 54: 1185-1188. DOI: https://doi.org/10.1093/jnci/54.5.1185
KITAGAWA T, SUGANO H. Enhancing effect of phenobarbital on the development of enzyme.aitered isiands and hepatocelular carcinomas initiated by 3-methyl-4-(dimethylamino)azobenzene or diethylnitrosamine. GANN 1978; 69: 679-687.
PUGH TD, GOLDFARB S. Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital. Cancer Res 1978; 38: 4450-4457.
WATANABE K, WILLIAMS GM. Enhancement of rat hepatocellular- altered foci by the liver tumor promoter phenobarbital: evidence that foci are precursors of neoplasms and that the promoter acts on carcinogen-induced lesions. JNCI 1978; 61: 1311-1314. DOI: https://doi.org/10.1093/jnci/61.5.1311
KITAGAWA T, PITOT HC, MiLLER EC, M1LLER JA. Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyi-N,N-dimothy1-4-aminoazobenzene in the rat. Cancer Res 1979; 39:112-115.
NiSHiZUMi M. Effect of phenobarbital, dichiorodiphenyitnchioroethane, and poiychioririated biphenyis on diethylnitrosamine-induced hepatocarcinogenesis. GANN 1979; 70: 835-837.
UCH1DA E, HIRUNO i. Effect of phenobarbital on induction of livor lung tumors by dimethylnitrosamide in newborn mico. GANN 1979; 70: 639-644.
KANEKO A, DEMPO K, KAKU T, YOKOYAMA S, SATOH M, MURI M, ONOE T. Effect of phenobarbital administration on hepatocytes constituting the hyperplastic nodules induced in rat livor by 3-methy1-4-dimethylaminoazebenzene, Cancer Res 1980; 40: 1658-1662.
NAR1TA T, WATANABE R, KITAGAWA T. Mechanisms of inhibition by simultaneously administered phenobarbital of 3'-methy1-4-(dimethylamino)azobenzene-induced hepatocarcinogenesis in the rat. GANN 1980,71: 755-758.
MUCHIZUKI Y, FURUKAWA K, SAWADA N, GOTOH M. Dose-dependent enhancing effect of phenobarbital on hepatocarcinogenesis initiated by diethylriitrosamíne in the rat. GANN 1981; 72: 170- 173.
UCHI DA E, H 1 RONO T. Effect 01 phenobarbital on the development of neoplastic lesions in the liver of cycasin-treated rats. J Cancer Res ClinOncol 1984; 100: 231-238. DOI: https://doi.org/10.1007/BF00410683
ALLEN B, LINDAHL R. Sequential 2-acethylaminofluorenephenobarbital exposure induces a cytosolic aldehyde dehydrogenase during rat hepatocarcinogenesis. Carcinogenesis 1982:3:533-538. DOI: https://doi.org/10.1093/carcin/3.5.533
MCLEAN AEM, SMITH M, DRIVER HE. Liver tumours alter single dose dimethylnitrosamine, 10w and high protein diet, and phenobarbitone. Carcinogenesis 1982; 3: 701-709. DOI: https://doi.org/10.1093/carcin/3.6.707
TAPER HS, LANS M, DE GERLACHEJ, FORT L, ROBERFOROID M. Morphological alterations and DNase deficiency in fenobarbital promotion of N-nitrosomorpholine initiated rat hepatocarcinogenesis. Carcinogenesis 1983; 4: 231-234. DOI: https://doi.org/10.1093/carcin/4.2.231
TSUDA H, FUKUSHIMA S, IMAIDA K, KURATA Y, TU N, Organ promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea. Cancer Res 1983: 43: 3292-3296.
WARD JM, RICE JM, CREASIA O, LYNCH P, RIGGS C. Dissimilar patterns of promotion by di(2-ethylhexyl)phtalate and fenobarbital of Aepatoceiuiar neoplasic initiated by diethylnitrosamine in B6C31=1 mice. Carcinogenesis 1983; 4: 1021-1029. DOI: https://doi.org/10.1093/carcin/4.8.1021
ITO W, MOORE MA, BANNASCH P. Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylaminofluorene, phenobarbital and 4,4'-diaminodiphenylmethane: a sequential histological and histochemical analysis. Carcinogenesis 1984; 5: 335-342. DOI: https://doi.org/10.1093/carcin/5.3.335
KITAGAWA T, HINO O, NOMURA K, SUGANO H. Dose-response studies on promoting and anticarcinogenic effects of fenobarbital and DDT in the rat hepatocarcinogenesis. Carcinogenesis 1984; 5: 1654-1656. DOI: https://doi.org/10.1093/carcin/5.12.1653
WILLIAMS GM, FURUVA K. Distinction between liver neoplasm promoting and syncarcinogenic effects demonstrated by exposure to phenobarbital or diethylnitrosamine either before or alter N-2-fluorenylacetamide. Carcinogenesis 1984; 5: 171-174. DOI: https://doi.org/10.1093/carcin/5.2.171
DIWAN BA, PALMER AE, OHSHIMA M, RICE JM. N-nitroso-W-methylurea initiation in multiple tissues for organ-specific tumor promotion in rats by phenobarbital. JNCI 1985; 75: 1099-1105.
DIWAN BA, RICE JM, OHSHIMA M, WARD JM. Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitrosodiethylamine and its promotion by phenobarbital in C5713LJ 6NCr, C31-1/HeNCrMTV- and DBA/2NCr mice. Carcinogenesis 1986,7: 215-220. DOI: https://doi.org/10.1093/carcin/7.2.215
DRIVER HE, MCLEAN AEM. Dose-response relationship for phenobarbitone promotion 01 liver tumours initiated by single dose dimethylnitrosamine. BrJ Exp Pathol 1986; 67: 131-139.
PERAINO C, CARNES BA, STEVENS FJ. Evidence for growth heterogeneity among foci with different phenotypes in the population 01 aitered hepotocyte foci induced by a single neonatal treatment with carcinogen. Carcinogenesis 1986; 7: 191-192. DOI: https://doi.org/10.1093/carcin/7.2.191
PEREIRA MA, KLAUNIG JE, HERREN-FREUND SL, RUCH RJ. Effect of phenobarbital on the development of liver tumors in juvenile and adult mice. JNCI 1986; 77: 449-452.
SOLT D, FARBER E. New principie for the analysis of chemical carcinogenesis. Nature 1976; 263: 701-703. DOI: https://doi.org/10.1038/263701a0
SOLTDB, MEDLIN A, FARBER E. Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am J Pathol 1977; 88: 595-618
OGAWA K, MEOLI NE A, FARBER E. Sequential analysis of hepatic carcinogenesis: the comparative architecture of preneoplastic, malignant, prenatal, postnatal and regenerative liver. Br J Cancer 1979; 40: 782-790. DOI: https://doi.org/10.1038/bjc.1979.261
OGAWA K, MEDLI NE A, FARBER E. Sequential analysis of hepatic carcinogenesis. A comparative study of the ultrastructure of preneoplastic, malignant, prenatal, postnatal and regenerating liver. Lab Invest 1979: 41: 22-35.
LEONARD TB, DENTJG, GRAINCHEV ME, LYGHT O, POPP JA. Comparison of hepatic carcinogen initiation-promotion systems. Carcinogenesis 1982; 3: 851 -856. DOI: https://doi.org/10.1093/carcin/3.8.851
HAYES MA, LEE G, TATEMATSU M, FARBER E. Influences of diethylnitrosamine on Iongevity of surrounding hepatocytos and progression of transplanted persistent nodules during fenobarbital promotion of hepatocarcinogenesis. Int J Cancer 1987; 40. 58-63. DOI: https://doi.org/10.1002/ijc.2910400111
GLAUERT HP, PITOT HC Influence 01 dietary fat on the promotion of diethylnitrosamine-induced hepatocarcinogenesis in female rats. Proc Soc Exp Biol Med 1986; 181 498-506. DOI: https://doi.org/10.3181/00379727-181-42283
FISCHER G, DOMINGO M, LOODER O, KATZ N, REINACHER M, EIGENBRODT E. ImmunohistochemicaI demonstration of decreased L-pyruvate kinase in enzyme altered rat liver lesions produced by differentcarcinogens. Virchows Arch B 1987; 53: 359-364. DOI: https://doi.org/10.1007/BF02890264
EVCES S, LINDAHL R. Changes in aldehyde dehydrogenase occurring during rat hepatocarcinogenesis induced by ethionine combined with dietary choline deficiency. Cancer Res 1986; 46: 3587-3592.
FARBER E, CAMERON R. The sequential analysis of câncer development. ADV Cancer Res 1980; 31:125-226. DOI: https://doi.org/10.1016/S0065-230X(08)60658-2
PITOT HC. The natural history of neoplasia. Newer insights Into na old problem. Am J Pathol 1977; 89: 402-411.
FARBER E. The pathology experimental liver cell cancer. In: CAMERON HM, LINSELL DA, WARWICK GP, eds. Liver CeIl Cancer. Amsterdam: Elsevier, 1976: 243-277. DOI: https://doi.org/10.1016/B978-0-444-41542-4.50014-6
KEISER CH, LOMBARD LS, MONTALI RJ, STEWART HL, WILLIAMS GM. Histology typing of liver tumors of the rat. JNCI 1980(64): 1076-206.
WILLIAMS GM. The pathogenesis of rat liver cancer caused by chemical carcinogens. Biochem Biophys Acta 1980; 605: 167-189. DOI: https://doi.org/10.1016/0304-419X(80)90003-7
SELL S, LEFFERT HL. An evaluation 01 cellular lineages in the pathogenesis of experimental hepatoceliular carcinoma. Hepatology 1982:3: 77-86. DOI: https://doi.org/10.1002/hep.1840020113
BAMNNASCH P. Sequential cellular changes during chemical carcinogenesis. J Cancer Res Clin Oncol 1934; 100: 11-22. DOI: https://doi.org/10.1007/BF00390968
SUMNER IG, LODOLA A. Total cytochrome P-450, but notthe major phenobarbitone or 3-mety1cholantrene induced isoerizyme is differentially induced in the lobes the rat liver. Biochem Pharmacol 1987: 36: 391-393. DOI: https://doi.org/10.1016/0006-2952(87)90300-5
RABES H, HARTENSTEIN R, SCHOLZE P. Specific stages of cellular response to homeostatic control during diethylnitrosamine-induced liver carcinogenesis. Experientia 1970; 26: 1356-1359. DOI: https://doi.org/10.1007/BF02113030
TSUDA H, MERA Y, SEKI K, AOKI T, FUKUSHIMA S, TU N. Induction of tumors in the liver, urinary bladder, esophagus and forestomach by short-term treatment with ditferent doses of N-N’ dibutylnitrosamine in rats. GANN 1987; 78: 227-234.
KUEN H, PUGH TD, GOLDFARB S. Hepatocarcinogenesis in the mouse. Am J Pathol 1983; 112: 89-100.
Carr BT. Experimental chemical hepatocarcinogenesis: early membrane changes of significance for drug resistence. J Cell Physiol (Suppl.) 1986; 4: 59-63. DOI: https://doi.org/10.1002/jcp.1041290412
RABES H M. Development and growth of early preneoplastic lesions nduced in the liver by chemical carcinogens. J Cancer Res Clin Oncol 1983; 106: 85-92. DOI: https://doi.org/10.1007/BF00395384
CAMERON R, FARBER E. Some conclusions derived from a liver model for carcinogenesis. Nati Cancer lnst Monogr 1981; 58: 49-53.
RICHARDSON FC, BOUCHERON JA, DYROFF MC, POPP JA, SWENBERG JA. Biochemical and morphologic studies of heterogeneous lobe responses in hepatocarcinogenesis. carcinogenesis 1986; 7: 247-251. DOI: https://doi.org/10.1093/carcin/7.2.247
