Glucagonoma Metastático Cerebral
DOI:
https://doi.org/10.32635/2176-9745.RBC.1987v33n2.3206Keywords:
Glucagonoma CerebralAbstract
Glucagonoma and its related syndrome are critically reviewed and up-dated. The authors present a case of glucagonoma syndrome with a pancreatic primary metastatic to the liverand a single cerebral metastasis with the presence of glucagon confirmed by immuno-histochemical studies. There was disease regression for at least 15 months after brain metastasis resection. This report could be the first one of a well-documented case of a glucagonoma with cerebral metastasis, inas-much review of the literature did not disclose a similar one.
Downloads
References
Broder SE, Carter SK - Pancreatic islei cell carcinoma II. Results of therapy with streptozotocin in 52 patients. Ann Int Med, 19731 79: 109-118
Becker SW, Kahb D, Rolhman S - Cutaneous manifestation of internal malignant tumors. Arch Dermatol, 1942, 42: 1069-1080 DOI: https://doi.org/10.1001/archderm.1942.01500120037004
McGavran MH, Unger RH, Recanl L, Polk HC, Kilo c; Levin ME - A glucagon-secreting alpha-cell carcinoma of the pancreas N Engi J Med, 1966, 274, 1408-1413. DOI: https://doi.org/10.1056/NEJM196606232742503
Muller WA, Falcona GR, Unger 6H - Hyperglucagonemia in diabetic ketoacidosis. Its prevalence and significance. Am .J Med, 1973; 54: 52.57. DOI: https://doi.org/10.1016/0002-9343(73)90083-1
Bilbrey GL, Falcona GR, White MG, Knochel JP, Borreto J - Hyperglucagonemia of renal failure. J Clin lnvest, 1974; 53. 841-847. DOI: https://doi.org/10.1172/JCI107624
Marco J, Javier Q Villanueva ML, Diaz-Fierros M, Valverde 1, Segovia J M - ElevaIed plasma glucagon leveIs in cirrhosis of lhe liver. N Eng J Med 1973; 289, 1107-1111. DOI: https://doi.org/10.1056/NEJM197311222892103
Wise JK, Hendler R, Felig P - Influence of glucocorlicoids on glucagon secretion and plasma amino acid concentrations in mar. J Clin lnvest, 1973; 52' 2774-2782. DOI: https://doi.org/10.1172/JCI107473
Sherwin RS, Fisher M, 'lendler R, Felig P Hyperglucagonemia and blood glucose regulatron in normal, obese and diabelic subjecls N Eng J Med, 1976; 294. 445-461 DOI: https://doi.org/10.1056/NEJM197602262940901
Church RE Crane WAJ A culaneous syndrome associated with islel-cell carcinoma of lhe pancreas Br J Dermatol, 1967, 79 284-286. DOI: https://doi.org/10.1111/j.1365-2133.1967.tb11492.x
Wilkinson DS - Necro:ytic migratory erylhema with pancrealic carcinoma. Proc R Soc Med, 1971, 64' 197-1198. DOI: https://doi.org/10.1177/003591577106401212
Sweet RE - A dermalosi specifically associaled with a tumor of pancreallc alpha celis. Br J Dermatol, 1974; 301-308 DOI: https://doi.org/10.1111/j.1365-2133.1974.tb06406.x
Mallinsor CN, Bloom SR, Warin AP, Salmon PR, Cox B - Agiucagonoma syndrome. LanceI, 1974; 2 1-5. DOI: https://doi.org/10.1016/S0140-6736(74)91343-9
Soler NG, Dates GD, Malins JM - Glucagonoma syndrome ir a young man Proc Roy Soc, 1976, 69' 429-431. DOI: https://doi.org/10.1177/003591577606900615
Yoshinaga 7, Okuno G, Sbinji Y, Isuju T, Nishikawa M - Pancrealic A-cell tumor associated with severe diabetes meilitus. Diabetes, 1966; 15' 709-713. DOI: https://doi.org/10.2337/diab.15.10.709
Gerich .JE, Lorenzi M, Bier DM etal - Prevenlion of buman diabelic keloacidosis by somatoslatir. evidence for ar essential role of glucagon. N Eng J Med, 1975; 292 985-989 DOI: https://doi.org/10.1056/NEJM197505082921901
Binnick AN, Spencer SK, Dennison GR .Jr, Horton ES - Glucagonoma Syndrome, Report of Iwo cases and lileralure review. Arch Dermatol, 1977; 113: 749-754 DOI: https://doi.org/10.1001/archderm.113.6.749
Swerson KH, Amor RB, Hsnifin JM - The glucagonoma syndrome. A distinctive cutarieous marker of systemic disease. Arch Dermatol, 1978; 114' 224-228. DOI: https://doi.org/10.1001/archderm.114.2.224
Rsbello FE - Nomenclatura dermatológica Rio de Janeiro, 1980; 288-289
Kaban RS, Perez-Figaredo RA, Neimanis A - Necrolytic migralory erythema. distinctive dermalosis of lhe glucagonoma syndrome. Arch Dermatol, 1977, 113 792-797. DOI: https://doi.org/10.1001/archderm.113.6.792
Norton iA, Kahn CR, Schebinger 9, Gorschbotb BS, Brennan MF Aminoacid deficiency in lhe skin rasi associated with glucagonorna. Ann ml Med, 1979,91 21 3-215. DOI: https://doi.org/10.7326/0003-4819-91-2-213
Aoki TT Muiler WA, Brennan MF, Cahill Jr GF - Effecl of glucagon cc aminoacid and nitrogen melabolism in fasting mar Metabolism, 1974; 23 805-814 DOI: https://doi.org/10.1016/0026-0495(74)90114-0
Tasrran-Jones C, Kay RG - Zinc deficiency and skin lesions. N Eng J Med, 1975, 293 830 DOI: https://doi.org/10.1056/NEJM197510162931616
Bhalhena SJ, Higgins JA, Recanl L. - Glucagonoma and glucagonoma syndrome Ir: Unger RH, Wrsi L, eds. Glucagon New York Elsevier, 1981; 413-439
Slapoole PW - The glucagonoma syndrome: Clinical 9-atures, diagnosis and treatment. Endoc Rev, 1981,3:347-361. DOI: https://doi.org/10.1210/edrv-2-3-347
Khandekar JD, 0yer D, Miliar HJ, Vick NA - Neurologic involvemenl in glucagonoma syndrome Resporise lo combination chemolherapy with 5-fluorouracil and slreptozolocir Cancer, 1979, 44: 2014-2016. DOI: https://doi.org/10.1002/1097-0142(197912)44:6<2014::AID-CNCR2820440608>3.0.CO;2-M
Domar RE, Shaffer Jr MB, Finks J, Sterir WK, Hursl CB - the glucagonoma syndrome Report of a case Arch inlerri Med, 1980; 140' 262-263. DOI: https://doi.org/10.1001/archinte.140.2.262
Fuiila J, Seino Y, lshida H et ai. - A functional study of a case of glucagonoma exhibitirg typical glucagonoma syndrome. Cancer, 1986; 57 860-865. DOI: https://doi.org/10.1002/1097-0142(19860215)57:4<860::AID-CNCR2820570429>3.0.CO;2-U
Prinz FIA, Badrinath K, Banerli M, Sparagana M, Dorsch IR, Laurence AM - Operative and chemolherapeutic managemenl of malignant glucagon producing tumors Surgery, 1981, 90: 713-719.
Victor M - Diseases of peripheral nervous syslem. Philadelphia: WB Saunders, 1975, vol ll 1030-1066.
Cruickshank EK - Neuromuscular disease in relation to nutrilion Fed Proc, 1961; 20 suppl. 7. 345-360.
Peraita M - Deficiency rieuropathies observed in Madrid during the civil war 1936-19391 Br Med J, 1946, 2: 784 DOI: https://doi.org/10.1136/bmj.2.4481.784
Simpson J - "Burning feet" in british prisoners-of-war in the lar east Lancet, 1946, 1.959-961. DOI: https://doi.org/10.1016/S0140-6736(46)91716-3
Spillane JD - Nulrilional disorders of lhe nervous syslem. Baltimore, Williams & Wilkins Co., 1947.
Whilfield RGS - Anomalous manifestations of mal nutrition in japanese prison camps. Br Med J, 1947; 2: 164-168. DOI: https://doi.org/10.1136/bmj.2.4517.164
Denny-Brown DE - Neurological conditions resulling from prolonged and severe dietary reslriclior Medicine, 1947; 26: 41-113. DOI: https://doi.org/10.1097/00005792-194702000-00002
Heninglon VM, Caroe E, DerbesV, Kennedy B. Ksashiokor – Report of four cases from Louisiana Arch Dermatol, 1958; 58: 157-170 DOI: https://doi.org/10.1001/archderm.1958.01560080015003
Kessiriger A, Lemon HM, Foiey JF - the glucagonoma syndrome and its mariagement. J Surg 0ncol, 1977; 9:419-424. DOI: https://doi.org/10.1002/jso.2930090502
Kurose 1, Seino 1, lshida H et al. - Sucessful treatment of melaslalic glucagonoma with dacarvazine. Lancet, 1984, 17: 621-622 DOI: https://doi.org/10.1016/S0140-6736(84)91011-0
Maryrrick SP, Fagadau WR, Duncan LA - Malignanl glucagonoma syndrome: response to chemotherapy. Ann ml Med, 1980; 93: 453-454. DOI: https://doi.org/10.7326/0003-4819-93-3-453
Boden G, Ryan IG, Eisenschmid BL, Shelmel JJ, Owen OE - IreatmenI of inoperable glucagonoma with lhe long-acling somaloslalin analogue SMS 201-995. N Eng J Med, 1986, 314: 1686-1689. DOI: https://doi.org/10.1056/NEJM198606263142606