Tumores Malignos do Intestino Delgado
DOI:
https://doi.org/10.32635/2176-9745.RBC.1987v33n3.3214Keywords:
Intestinal Tumours, Cancer of the Small BowelAbstract
Primary malignant tumours of the small intestine are uncommon and are often diagnosed at na advanced stage. Seventeen cases of malignant tumours of the small intestine were encountered over a 27-year period in the Serviço de Cirurgia from Ribeirão Preto. The ileum was the most common location, with a decreasing frequency proximally. Synchronous tumours were found in 35.29% of the patients. Presenting signs and symptoms were vague and related mainly to abdominal pain (94.12%), nausea and vomiting (52.94%), weight loss (52.94%), and anorexia (35.29%). An abdominal tumour was evident in 35.29910 of patients. Three patients presented with perforation of the tumour, one of them af ter radiotherapy. Barium contrast examination was the primary complementary diagnostic modality. The treatment was wide resection of bowel and mesentery, whenever possible, for jejunal and ileal tumours, together with resection of other involved organs. In one case only biopsy could be perforrned. Lymphoma was the most common malignancy, followed by leiomyosarcoma and adenocarcinoma. The operative mortality was 23.53% (4 patients), 3 from sepsis (two opera ted on with peritonitis) and one from anesthetic problem. Adjuvant radiotherapy and/or chemotherapy was used in the patients who survived surgery except in one. AlI leiomyosarcoma recurred and the patients were opera ted on again with a new resection. Four patients are alive from 2 to 15 years af ter surgery The 5-year survival rate for the lymphomas is 25% (38% if the operative deaths are excluded), and for the adenocarcinoma is 100% (only 2 cases). Whereas the symptoms are vague, the diagnostic of small bowel tumour must be cogitated if the prognosis is to be improved.
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References
Akwari OE, Dozois RR, Weiland LH, Beahrs OH - Leiomyosarcoma of the Small and Large Bowel. Cancer, 1978; 42:13751384. DOI: https://doi.org/10.1002/1097-0142(197809)42:3<1375::AID-CNCR2820420348>3.0.CO;2-4
Anschutz JA, Torres 8H, Longo CA, Sanguineri HEM, Pesca MA -. Tumores del intestino delgado Prensa Méd. Argent., 1984; 71:449-451.
Arthaud J B, Guinee VF - Jejunal and ileal Adenocarcinoma. Epidemiological Considerations. Am. J. Gastroenterol, 1979; 72:638.646.
Awrich AE, lrish CE, Vetio RM, Fletcher WS - A Twenty-Fise Year Experience with Primary Malignant Tumours of the Small Intestine. Surg Gynecol Obstet, 1980; 151.914.
Braasch JW, Oenbo HE - Tumours of the Smatl Intestine. Surg Clin North Am, 1964, 44791-809
Bridge ME, Perzin KH - Primary Adenocarcinoma 01 the Jejunum and Ileum. A Clinico pathologic Study. Cancer, 1975, 36:1873-1887. DOI: https://doi.org/10.1002/1097-0142(197511)36:5<1876::AID-CNCR2820360545>3.0.CO;2-7
Brookes JS, Waterhouse JAH, Poweli DJ - Malignant Lesions of the Small Intestine. A 10-Year Survey. Br J Surg, 1968; 55:405.410. DOI: https://doi.org/10.1002/bjs.1800550602
Brumini R, Torloni H, Henson DE, Glotiieb SLD, Souza JMP - Câncer no Brasil. Dados histológicos 1976-1980 Ed DATAPREV, Rio de Janeiro, 1982.
Calman KC - Why are Small Bowel Tumours Rare2 An Experimental Modei. Gut, 1974; 15.552-554. DOI: https://doi.org/10.1136/gut.15.7.552
Oawson IMP, Coroes JS, Morson BC - Primary Malignant Lymphoid Tumours of the Intestinal Tract, Br J Surg, 1961; 49:80-83 DOI: https://doi.org/10.1002/bjs.18004921319
Deck KB, Silberman H Leiomyosarcomas of lhe Small Intestine Cancer, 1979, 44:323-325. DOI: https://doi.org/10.1002/1097-0142(197907)44:1<323::AID-CNCR2820440155>3.0.CO;2-G
Ebert PA, Zuidema GO - Primary Tumours of lhe Small Intestine. Arch Surg, 1965; 91 452-456. DOI: https://doi.org/10.1001/archsurg.1965.01320150082012
Freund H, Lavi A, Pfeffermann R, Durst A - Primary Neoplasma of the Small Bowel Am J Surg, 1978; 135- 757 759 DOI: https://doi.org/10.1016/0002-9610(78)90158-7
Giuliani A, Caporale A, Tenerielio E, Alessi G, Serpieri S, Sammartino P – Primary Tumours of the Small Intestine. int Surg, 1985; 70:331 -334
Goel IR, Didolkar MS, Eles EG - Primary Malignant Tumours of lhe Small Intestine Surg Gynecol Obstet, 1976; 143:717-719.
Jigyasu O, Bedikian AY, Stroehlein JR - Chemotherapy for Primary Adenocarcinoma of lhe Small Bowel. Cancer, 1984; 53:23.25 DOI: https://doi.org/10.1002/1097-0142(19840101)53:1<23::AID-CNCR2820530106>3.0.CO;2-U
Lowenfels AB - Why are small bowel tumours se raro? Lancet, 1973, 124-26. DOI: https://doi.org/10.1016/S0140-6736(73)91228-2
Miles RM, Crawford O, Duras S -. 'he Small Bowel Tumor Problem. Ann Surg, 19791 189:732-740. DOI: https://doi.org/10.1097/00000658-197906000-00009
Miltal VK, Bodzin JH Primary Malignant Tumours of the Small Bowel, Am J Surg, 19801 140.396 399. DOI: https://doi.org/10.1016/0002-9610(80)90176-2
Ouriel K, Adams JT - Adenocarcinoma of the SmaIl Intestine. Am J Surg, 1984; 14766-71.
Ragtalunan RJG, Mayo CW, Dockerty MB - Primary Malignant Tumours of the Small Intestine. Am J Surg, 1964; 10813-18
Ranchod M, Kempson RL - Smooth Muscle Tumours of the gastrointestinal Tract and Retroperitoneum. A Pathologic Analysis of 100 Cases. Cancer, 1977; 39255-262. DOI: https://doi.org/10.1002/1097-0142(197701)39:1<255::AID-CNCR2820390139>3.0.CO;2-H
Ramot B, Shahin N, Bubus JJ Malabsorption Syndrome in Lympboma of Small Intestine. A study of 13 Cases. Isr J Med Sci, 19651 2:221-226
River L, Silverstein J, Tope JW -- Coilective Review: Benign Neoplams of the Small Intestine. A Comprehensive Review with Report of 20 New Cases. Int Abstr Surg, 1956; 102:1-38
Sandoval MGD, Padiíha FA, Chianale JB, Accatino LL, Duarte IG, Garcia C - Tumores del intestino delgado. Rev Méd Chile, 1984; 112.1220-1224.
Samson RR, Mc Clelland DBL, Shearman DJC - Studies on the Quantitation lo lmmunoglobuhn in Human Intestinal Secretion. Gut, 1973, 14.616-626. DOI: https://doi.org/10.1136/gut.14.8.616
Starr GF - Rsthologic Features 01 Smooth Muscle Tumours. JAMA, 1974; 229 :12 19-1220. DOI: https://doi.org/10.1001/jama.229.9.1219
Todeschini LR, Zilio PV, Furtado ARA, Todeschini LA Linfoma linfo-histiocítico do intestino delgado. Relato de um caso. Rev Imagem, 1984; 6:89-92
Wattenberg LW - Carcinogen-Detoxifying Mechanisms in the Gastrointestinal Tract. Gastroenterology, 1966; 51 :932-937 DOI: https://doi.org/10.1016/S0016-5085(19)34345-8
Wattenberg LW - Studies of Polycyclic Hydrocarbon hydrosylases of lhe Intestine Possibly Related to Cancer. Cancer, 1971; 28.99-102 DOI: https://doi.org/10.1002/1097-0142(197107)28:1<99::AID-CNCR2820280118>3.0.CO;2-M
Williamson RCN, Welch CE, Malt RA - Adenocarcinoma and Lymphoma of the Small Intestine. Distributiori and Etiologic Associations Ann Surg, 1983; 197172-178.
Wilson JM, Melvin DB, Gray GF, Thorbjarnarson B - Primary Malignancies of lhe Small Bowel. A Report of 96 Cases and Review of the Literature. Ann Surg, 1974; 180:175-179 DOI: https://doi.org/10.1097/00000658-197408000-00008