A Linhagem Linfóide: Para Correlação com as Doenças Linfoproliferativas Malignas
DOI:
https://doi.org/10.32635/2176-9745.RBC.1986v32n4.3283Keywords:
Immunologic Phenotype, Monoclonal Antibodies, Lymphoid LineageAbstract
The presente text is a review of current knowledge on normal lymphoid lineage. Recent developments in this field were mainly due to the identification of molecules on lymphoid cells surfaces through monoclonal antibodies The development of lymphoid lineage is depicted and axis T and axis B are shown, as well as the differentiation steps from the most primitive to the most mature cell. Blastic transformation steps are also discussed since its beginning after contact between lymphocite and antigen. The author states that minute knowledge of lymphoid lineage is basic to malignant lymphoproliferative diseases classification.
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