Metabólito do Ácido Fólico Inibidor da Xantina Desidrogenase em Células Tumorais
DOI:
https://doi.org/10.32635/2176-9745.RBC.1982v29n2.3539Keywords:
Xanthine Oxidase, Neoplasms, Folic AcidAbstract
Malignant cells excrete into their growth médium a xanthine dehydrogenase inhibitor. This catabolite was not found in peritoneal exsudate induced by non-tumoral antigen and in the supernatant fluid of lymphocytes culture. The XD inhibitor is a dialyzable factor, probably 6-OH-pterin.
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