Role of Histones ín Cell Division and Differentiation. I — Study of Percent Differences Between Histones of Normal Rat Liver and Ehrlich Ascitic Tunor Cell
DOI:
https://doi.org/10.32635/2176-9745.RBC.1968v24n38.4006Keywords:
Histones, Cell Differentiation, Carcinoma, Ehrlich TumorAbstract
Histone fractions from normal rat liver has shown quantitative variations when compared to those extract from Ehrlich ascitis tumor cells. The fx fractions is percentually increased in Ehrlich tumor, while fractions f2 and f3 are increased in the normal liver. Possible implications of these findings in the regulation of cell dlvision are discussed.
Downloads
References
BONNER, J. & HUANG, R. C.: Histones as specific repressors of chromosoraal RNA synthesis. Giba Foundation Studv Group nr. 24. 18, 1966.
BLOCH, d. P., in J. Bonner and P.O.P. Ts’o eds, The nucleohistones holden-day. San Francisco, 1964.
CRAMPTON, C. F.; STEIN, W. H. & MOORE, S.; Comparative studies on cromatographically purified histones. J. Biol. Chem., 225: 363, 1957. DOI: https://doi.org/10.1016/S0021-9258(18)64938-5
DAVISON, P. F.: Chromatography of histones Biochim. J., 66: 708, 1957. DOI: https://doi.org/10.1042/bj0660708
DAVIS, J. R. & BUSCH, H.: Chromatographic analysis of radioactive cationic nuclear proteins of tissues of tumor-rearing rats. Câncer Res. 20: 291, 1960.
GOODWIN, B. C.: Histones and reliable control of protein synthesis. Ciba Foundation Study Group nr. 24: 68, 1966.
HNILICA, L.; JOHNS, E. W. & BUTLER, J. A. V.: Observation on the spacies and tissue specificity of histones. Biochim. J., 82: 123, 1962. DOI: https://doi.org/10.1042/bj0820123
HOGBOON G. H,: Isolation of liver cell nuclei in an aquos médium in Methods in Enzymology. First Edition. N. V. Academic Press. New York, 1955.
JOHNS, E. W.: Studies on histones: 7 — Preprative methods for histones fractions from caU thymus. Biochim. J., 92: 55, 1964. DOI: https://doi.org/10.1042/bj0920055
JONS, E. W.; PHILIPS, D.M.P.: SIMSON, P. & BUTLER, J.A.V.: Improved fractionations of arginine-rich histones from calf thymus. Biochim. J., 77: 631, 1960. DOI: https://doi.org/10.1042/bj0770631
MARUSHIGE, K. & BONNER, J.: Template properties of liver chromatin. J. Molec Biol., 15: 160, 1966. DOI: https://doi.org/10.1016/S0022-2836(66)80218-8
NEELIN, J. M. & CONNELL, G. E.: Zone electrophoresis of chicken erythrocyte histone in starch gel. Biochim. Biophys. Aeta, 31: 539, 1959. DOI: https://doi.org/10.1016/0006-3002(59)90030-7
PHILLIPS, D. M. P. & JOHNS, E. W.: A study of the protainase content and the cromatography of thymus histones. Biochim. J., 72: 538, 1959. DOI: https://doi.org/10.1042/bj0720538
PALAU, J. & BUTLER, J. A. V.: Histone of traut liver. Biochim. J., 100: 779, 1966. DOI: https://doi.org/10.1042/bj1000779
REID B. R.; STELLWAGEN, R. H. & COLE, R. R.: Further Studies on the biosynthesis of very lysine-rich histone in isolated nuclei. Biochem. Biophys. Acta, 155: 593, 1968. DOI: https://doi.org/10.1016/0005-2787(68)90202-5
STARBUCK, W. C. & BUSCH: Kinetics of Incorporation of L-arginine U-C14 into nuclear proteins of tumor and other tissues in vitro. Câncer Res., 20: 891, 1960.
SHERBERT, G. V.: Effects of histones and otrer inhibitors on embryonic development. Ciba Foundation Study Group nr. 24: 81, 1966.
VENDRELY, R.; KNOBLOCH, A. & MATSUDAIRA, H.: A comparative biochemical study of nucleohistones from different vertebrates. Nature. 181: 343, 1958. DOI: https://doi.org/10.1038/181343a0
Downloads
Published
How to Cite
Issue
Section
License
Os direitos morais e intelectuais dos artigos pertencem aos respectivos autores, que concedem à RBC o direito de publicação.
This work is licensed under a Creative Commons Attribution 4.0 International License.
