Therapeutic and Diagnostic Procedures to be Followed in Linfomas and Leukemia

Authors

  • Antonio Pinto Vieira Chefe. Instituto de Câncer. Serviço Nacional de Câncer. Rio de Janeiro (RJ), Brasil.
  • Emmanuel Rebello Chefe. Laboratório de Patologia Clínica. Instituto de Câncer. Rio de Janeiro (RJ), Brasil.
  • Jacyr Antonio Abbud Internista. Instituto de Câncer. Rio de Janeiro (RJ), Brasil.

DOI:

https://doi.org/10.32635/2176-9745.RBC.1956v13n14.4038

Keywords:

Hodgkin Disease/diagnosis, Hodgkin Disease/therapy, Lymphoma, Non-Hodgkin, Leukemia/diagnosis, Leukemia/therapy, Electrophoresis, Bone Marrow Examination

Abstract

The authors consider the following diseases as lymphomas — Bryll Symmers — (macrofolicular lymphoma), Hodgkin's disease, retículum-cell sarcoma and Iymphosarcoma. Classifications for Iymphoma and leukemia are given. Besides the classical semiotic means for diagnosis other auxiliary examinations are analvysed such as pathological examination, hematological findings and radiological examination. Among these diagnostic means electrophoresis and boné marrow aspiration are described with greater detail because they represent nowdays a subject of great interest. The different bone marrow findings on lymphomas and leukemia are described. The electrophoretic curve is studied in detail. In this work two types of instruments were used: a) Kern LK 30, Tiselius type which gives electrophoresis with very small amount of serum and b) Wieland-Fischer's apparatus, in which the protein mollecules migration is made over filter paper. Electrophoretic values are also given in the different types of lIymphomas and leukemia. The authors also give the following treatment table of their own: I Treatment by irradiation. II Chimiotherapic treatment. III Surgical treatment. IV Complemenctary treatment. Irradiation treatment is studied in regard to the different radio-active isotopes and also the different roentgenterapeutic tecniques employed in these diseases. Chemiotherapeutic treatment is divided in 4 groups: radiomimetic substances, cytotoxic substances, antimetabolic substances and hormones. In this chapter the doses of the most important drugs used to treat such illnesses are given. As a complementary treatment the authors discuss and give their own experience regarding, exosanguineo transfusion, blood transfusion and antibiotics. Prognosis is given in detail. They refer to several cases of chronic granulocitic leukemia, lymphosarcoma reticulum-cell sarcoma and Hodgkin's disease treated by X-Ray and chemiotherapy with a survival of over 5 years. Numerous photographis, X-ray pictures of patients and also microphotografic findings are given in the article.

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References

AZEVEDO, S.: Quimioterapia do Câncer. Relatório oficial apresentado ao VI Congresso Internacional de Câncer, São Paulo, 1954. Revista Brasileira de Cancerologia, Vol. 11, N.º 12, pgs. 7-26, 1954. DOI: https://doi.org/10.32635/2176-9745.RBC.1954v11n12.4175

BESSIS, M. et DAUSSET, J.° Etude critique des remissions au cours des leucémies traitées par exsanguino-transfusions. Rev. d'hemat. 5: 188-225, 1950.

CRAVER, L. F.: Lymphomas and Leukemias, Bull, of N.Y. Red. of Med. 23: 79, 1947.

Treatment of Cancer and Allied Diseases, New York, 1950, Paul B. Hoeber Inc., Vol. 3, 2487-2506.

CUSTER, R. P.: An atlas of the Blood and Bone Marrow, Saunders Co. Phila. 1949.

FOSTER, C. G. and MULLER, F. R.: Presence of myelokentric and lymphokentric in sera of patients with Iymphomatoid diseases. Proc. Soc. Exper. Biol. E. Med. 75: 6338, 1950. DOI: https://doi.org/10.3181/00379727-75-18288

GALL, E. A. and MALLORY, L. B.: Malignant Lymphoma. Am. Jour. Path. 18: 38, 1942.

JACKSON, H. JR.: The Leukemias, New: Eng. J. Med. 22: 22-28, 1940. DOI: https://doi.org/10.1056/NEJM194001042220104

LEITNER, S. J.: Bone Marrow Biopsy. J. A. Churchill Ltda., London, 1949.

LUMB, G : Tumours of Lymphoid tissue. Ed. William & Wilkins Co., 1954.

Mc GRAVAN, C. W.: Lymphatic Leukemia of twenty five years duration. Ann. Int. Med. 12: 396-402, 1938. DOI: https://doi.org/10.7326/0003-4819-12-3-396

MEYER, J. R.: Arquivos do Inst. Biol. São Paulo, 16: 307, 1945.

MILLS, S. D.: Acute Lymphatic Leukemia in Childhood. J. Ped. 6: 634-643, 1935. DOI: https://doi.org/10.1016/S0022-3476(35)80057-7

MOESCHLIN, S.: La puncion del bazo. Edic. Morata, Madrid, 1951 (Trad. original alemão).

REBELLO, E., FIALHO, F. e MACHADO, O.: Hiperplasias e neoplasias dos órgãos linfopoéticos. Diagnóstico e tratamento pelas radiações. Rev. Bras. Canc., Vol. 7, No. 10, pgs. 5-126, 1953. DOI: https://doi.org/10.32635/2176-9745.RBC.1953v7n10.4190

REBELLO, E.: L'Electrophorese dans les lymphomes. Unio Internationalis contra cancrum. Acta 11 (3): 302-312, 1955.

SANTOS SILVA, M.: Linfomas. Estudo clínico. Rev. Bras. Med. IX: 536, 1952.

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Published

2023-09-14

How to Cite

1.
Vieira AP, Rebello E, Abbud JA. Therapeutic and Diagnostic Procedures to be Followed in Linfomas and Leukemia. Rev. Bras. Cancerol. [Internet]. 2023 Sep. 14 [cited 2024 Nov. 26];13(14):5-35. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4038

Issue

Vol. 13 No. 14 (1956): June

Section

ORIGINAL ARTICLE

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