Work- related hematologic cancers identifiet in patients at Hospital do Câncer I at Instituto Nacional de Câncer, RJ,Brazil
DOI:
https://doi.org/10.32635/2176-9745.RBC.2024v70n4.4710Keywords:
Occupational Cancer, Occupational Risks, Surveillance of the Workers Health, Hematologic NeoplasmsAbstract
Introduction: Cancer is a disease with global public health impact and the work environment can have high concentrations of physical, chemical and biological agents, exposing workers to carcinogens. Objective: To evaluate the profile of cases of hematological cancers suspected of being work-related cancer. Method: Assessment of sociodemographic and occupational data of patients with hematological cancers to elaborate the occupational history followed by analysis of the relationship between exposure to carcinogens and cancer, considering the epidemiological criteria of temporality, biological plausibility and consistency. Results: 22 cases evaluated demonstrated a relationship between cancer and occupational exposure, the main agents being benzene, solvents, oils, petroleum derivatives and formaldehyde, non-ionizing radiation and glues. Conclusion: Occupational exposure may contribute to the occurrence of work-related cancer. The occupational record is an important tool for establishing the cause-and-effect relationship between exposure to risk factors and hematological cancers, helping health professionals in the process of notifying these cases in Brazil.
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Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A Cancer J Clin. 2021;71(3):209-49. doi: https://doi.org/10.3322/caac.21660. DOI: https://doi.org/10.3322/caac.21660
Instituto Nacional de Câncer. Estimativa 2023: incidência de câncer no Brasil. Rio de Janeiro: Instituto Nacional de Câncer; 2022. DOI: https://doi.org/10.32635/2176-9745.RBC.2000v46n1.3398
World Health Organization. WHO report on cancer: setting priorities, investing wisely and providing care for all. Geneva: World Health Organization; 2020.
Hoff PMG. Tratado de oncologia. 1. ed. São Paulo: Atheneu; 2013. 2893p.
Iavicoli S, Driscoll TR, Hogan M, et al. New avenues for prevention of occupational cancer: a global policy perspective. Occup Environ Med. 2019;76(6):360-2. DOI: https://doi.org/10.1136/oemed-2018-105546
Cogliano VJ, Baan R, Straif K, et al. Preventable exposures associated with human cancers. J Natl Cancer Inst. 2011;103:1827-39. DOI: https://doi.org/10.1093/jnci/djr483
International Agency for Research on Cancer. Chemical agents and related occupations. IARC monographs on the evaluation of carcinogenic risks to humans volume 100F [Internet]. Lyon: IARC; 2012. [acesso 2024 mar4]. Disponível em: https://publications.iarc.fr/123
Wünsch Filho V. Surveillance of work-related cancer: on the 2012 guide published by INCA (Brazilian National Cancer Institute). Rev Bras Saude Ocup. 2012;37:125. DOI: https://doi.org/10.1590/S0303-76572012000100001
Amstar: Assessment of Multiple Systematic Reviews [Internet]. Ottawa: Instituto de Pesquisa Bruyère; ©2024. [acesso 2024 mar 4] Disponível em: http://amstar.ca/Amstar_Checklist.php
Instituto Nacional de Câncer José Alencar Gomes da Silva. Diretrizes para vigilância do câncer relacionado ao trabalho. Rio de Janeiro: INCA; 2013. DOI: https://doi.org/10.32635/2176-9745.RBC.2012v58n2.1427
Baldo RCS, Romaniszen CSR, Spagnuolo RS, et al. Nexo epidemiológico do câncer relacionado ao trabalho no município de Londrina-PR. Rev Bras Cancerol. 2021;67(3):e-141328. doi: https://doi.org/10.32635/2176-9745.RBC.2021v67n3.1328 DOI: https://doi.org/10.32635/2176-9745.RBC.2021v67n3.1328
Organização Mundial da Saúde. CID-10: Classificação Estatística Internacional de Doenças e Problemas Relacionados à Saúde. tradução Centro Colaborador da OMS. 8 ed. rev. e ampl. São Paulo. Editora da Universidade de São Paulo; 2012. Vol.1.
EPIINFO 7 [Internet]. Belo Horizonte: Secretaria de Estado de Saúde; 2017. [acesso 2024 ago 15]. Disponível em: http://vigilancia.saude.mg.gov.br/index.php/download/instalador-epiinfo-7/
Conselho Nacional de Saúde (BR). Resolução n° 466, de 12 de dezembro de 2012. Aprova as diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos. Diário Oficial da União, Brasília, DF. 2013 jun 13; Seção I:59.
Vazquez FL, Silveira HC, Otero UB, et al. The usefulness of an online simplified screening questionnaire (SSQ) in identifying work-related cancers. Healthcare. 2023;11(11):1563. doi: https://doi.org/10.3390/healthcare11111563 DOI: https://doi.org/10.3390/healthcare11111563
Wild CP, Weiderpass E, Stewart BW, editores. World cancer report: cancer research for cancer prevention [Internet]. Lyon: International Agency for Research on Cancer; 2020. [acesso 2024 mar 4] Disponível em: https://publications.iarc.fr/Non-Series-Publications/World-Cancer-Reports/World-Cancer-Report-Cancer-Research-For-Cancer-Prevention-2020
American Cancer Society [Internet]. Atlanta: ACS; ©2024. Viruses that can lead to câncer, 2023 mar 21.[acesso 2024 mar 4]. Disponível em: https://www.cancer.org/cancer/risk-prevention/infections/infections-that-can-lead-to-cancer/viruses.html
Rodriguez-Abreu D, Bordoni A, Zucca E. Epidemiology of hematological malignancies. Ann Oncol. 2007;18(Sup1):i3-8. doi: https://doi.org/10.1093/annonc/mdl443 DOI: https://doi.org/10.1093/annonc/mdl443
Otero UB, Mello MSC. Fração atribuível a fatores de risco ocupacionais para câncer no Brasil: evidências e limitações. Rev Bras Cancerol. 2016;62(1):43-5. doi: https://doi.org/10.32635/2176-9745.RBC.2016v62n1.385 DOI: https://doi.org/10.32635/2176-9745.RBC.2016v62n1.385
Sales-Fonseca N, Otero UB, Koifman RJ, et al. Benefícios acidentários e previdenciários concedidos a portadores do câncer no Brasil, 2008-2014. Ciênc saúde coletiva. 2023;28(2):447-57. doi: https://doi.org/10.1590/1413-81232023282.11532022 DOI: https://doi.org/10.1590/1413-81232023282.11532022en
Langard S, Lee L. Methods to recognize work-related cancer in workplaces, the general population, and by experts in the clinic, a Norwegian experience. J Occup Med Toxicol. 2011;6(24):1-10. doi: https://doi.org/10.1186/1745-6673-6-24 DOI: https://doi.org/10.1186/1745-6673-6-24
Azevedo e Silva G, Moura L, Curado MP, et al. The fraction of cancer attributable to ways of life, infections, occupation, and environmental agents in Brazil in 2020. PLoS One. 2016;11(2):e0148761. doi: https://doi.org/10.1371/journal.pone.0148761 DOI: https://doi.org/10.1371/journal.pone.0148761
Poynter JN, Richardson M, Roesler M, et al. Chemical exposures and risk of acute myeloid leukemia and myelodysplastic syndromes in a population-based study. Int J Cancer. 2017;140(1):23-33. doi: https://doi.org/10.1002/ijc.30429 DOI: https://doi.org/10.1002/ijc.30420
Wong O, Harris F, Armstrong TW, et al. A hospital-based case-control study of acute myeloid leukemia in Shanghai: analysis of environmental and occupational risk factors by subtypes of the WHO classification. Chem Biol Interact. 2010;184(1-2):112-28. doi: https://doi.org/10.1016/j.cbi.2009.12.005 DOI: https://doi.org/10.1016/j.cbi.2009.10.017
Howard J. Minimum latency & types or categories of cancer. Replaces administrators’ white paper on minimum latency & types of cancer. CDC [Internet]. 2013[acesso em 2024 mar 4];128-47. Disponível em: https://www.cdc.gov/wtc/pdfs/policies/WTCHP-Minimum-Cancer-Latency-PP-01062015-508.pdf
Khalade A, Jaakkola MS, Pukkala E, et al. Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. Environ Health. 2010;9(31):1-8. doi: https://doi.org/10.1186/1476-069X-9-31 DOI: https://doi.org/10.1186/1476-069X-9-31
Zhang L, Steinmaus C, Eastmond DA, et al. Formaldehyde exposure and leukemia: a new meta-analysis and potential mechanisms. Rev Mutat Res. 2009;681(2-3):150-68. doi: https://doi.org/10.1016/j.mrrev.2008.07.002 DOI: https://doi.org/10.1016/j.mrrev.2008.07.002
Boniol M, Koechlin A, Boyle P. Meta-analysis of occupational exposures in the rubber manufacturing industry and risk of câncer. Int J Epidemiol. 2017;46(6):1940-9. doi: https://doi.org/10.1093/ije/dyx191 DOI: https://doi.org/10.1093/ije/dyx146
Hauptmann M, Daniels RD, Cardis E, et al. Epidemiological studies of low-dose ionizing radiation and cancer: summary bias assessment and meta-analysis. J Natl Cancer Inst Monogr. 2023;2023(61):e1. doi: https://doi.org/10.1093/jncimonographs/lgac027 DOI: https://doi.org/10.1093/jncimonographs/lgac027
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