Cancer Control in the 21st Century: Global Challenges Demand Collective Solutions
DOI:
https://doi.org/10.32635/2176-9745.RBC.2025v71n4.5436Keywords:
Neoplasms/prevention & control, Global Health, Health Equity, Health PolicyAbstract
Cancer emerges as one of the main global health threats in the 21st century, 35 million new cases are expected until 2050. Mortality, however, is distributed unfairly: while high income countries exhibit high incidence, low and middle income countries as Brazil present elevated mortality rates, exposing problems of access and effectiveness of health systems in these regions. The high costs of new treatments is another challenge because these innovations are not an “universal solution” and strengthen the necessity of a social reflection and pursue of a new funding and assistance model focused to partnerships and accessibility. It is crucial to redesign the logic of health care, prioritizing the patient and integrated planning of oncologic attention utilizing data and systems based on interoperability to optimize prevention and cancer control. Fight against cancer demands collective and purposeful action. Strategic and bioethical decisions involving all social players are fundamental to prioritize prevention, early detection and equitable access to effective treatments.
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References
Wild CP, Weiderpass E, Stewart BW, editors. World Cancer Report: cancer research for cancer prevention. Lyon: International Agency for Research on Cancer; 2020.
GLOBOCAN 2022: Latest global cancer data shows rising incidence and stark inequities. UICC [Internet]. 2024 fev 1. [Acesso 2025 jan 10]. Disponível em: https://www.uicc.org/news-and-updates/news/globocan-2022-latest-global-cancer-data-shows-rising-incidence-and-stark
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. doi: https://www.doi.org/10.3322/caac.21660 DOI: https://doi.org/10.3322/caac.21660
Global Burden of Disease Cancer Collaboration; Fitzmaurice C, Abate D, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: a systematic analysis for the global burden of disease study. JAMA Oncol. 2019;5(12):1749-68. doi: https://www.doi.org/10.1001/jamaoncol.2019.2996
Leighl NB, Nirmalakumar S, Ezeife DA, et al. An arm and a leg: the rising cost of cancer drugs and impact on access. Am Soc Clin Oncol Educ Book. 2021;41:1-12. doi: https://www.doi.org/10.1200/EDBK_100028 DOI: https://doi.org/10.1200/EDBK_100028
Sullivan R. Affordable cancer care: a global mirage? Cancerworld [Internet]. 2016 abr 12. [Acesso 2024 jul 22]. Disponível em: https://archive.cancerworld.net/our-world/affordable-cancer-care-a-global-mirage/
Light DW, Lexchin JR. Pharmaceutical research and development: what do we get for all that money? BMJ. 2012;345:e4348. doi: https://www.doi.org/10.1136/bmj.e4348 DOI: https://doi.org/10.1136/bmj.e4348
Tanenbaum SJ. What is patient-centered care? a typology of models and missions. Health Care Anal. 2015;23(3):272-87. doi: https://www.doi.org/10.1007/s10728-013-0257-0 DOI: https://doi.org/10.1007/s10728-013-0257-0
Hill E. Slow medicine. J Am Board Fam Med. 2021;34(4):871-3. doi: https://www.doi.org/10.3122/jabfm.2021.04.200477 DOI: https://doi.org/10.3122/jabfm.2021.04.200477
Shulman LN. The effect of accountable care organizations on oncology practice. Am Soc Clin Oncol Educ Book. 2014:e468-71. doi: https://www.doi.org/10.14694/EdBook_AM.2014.34.e468 DOI: https://doi.org/10.14694/EdBook_AM.2014.34.e468
Santini L. Luiz Santini: 'Brasil tem boa estrutura para tratamento de câncer; acesso é o grande desafio'. [Entrevista a Eliane Bardanachvili]. Jornal da CEE Fiocruz (Conjuntura Política) [Internet]. 2019 nov 5. [Acesso 2025 jan 10]. Disponível em: https://cee.fiocruz.br/?q=node/1072
Santos MO, Lima FCS, Martins LFL, et al. Estimativa de incidência de câncer no Brasil, 2023-2025. Rev Bras Cancerol. 2023;69(1):e-213700. doi: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700 DOI: https://doi.org/10.32635/2176-9745.RBC.2023v69n1.3700
Movimento Todos Juntos Contra o Câncer. Financiamento em saúde # 38 [com Luiz Santini] [podcast]. Movimento Todos Juntos Contra o Câncer. TJCC; 2024. Disponível em: https://tjcc.com.br/acontece-tjcc/tjccnoar-financiamento-em-saude-dados-x-sus/
Callahan D. Setting limits: medical goals in an aging society. New York: Simon and Schuster; 1987.
Sullivan R. Value and cancer – this is how we reverse the decline. Cancerworld [Internet]. 2018 mar 9. [acesso 2024 jul 22]. Disponível em: https://archive.cancerworld.net/comment/value-and-cancer-this-is-how-we-reverse-the-decline/
Szklo M. Moyses Szklo: participação do mercado na produção do conhecimento torna distorcido o processo de tradução de conhecimentos. ABRASCO (Notícias) [Internet]. 2015 jul 27. [acesso 2024 jul 22]. Disponível em: https://abrasco.org.br/moyses_szklo_abrascao/
Temporão JG, Santini LA. Novas tecnologias na saúde e o desafio do acesso com equidade. [Entrevista a Eliane Bardanachvili]. Jornal da CEE Fiocruz (Saúde e sustentabilidade) [Internet]. 2022 ago 1. [Acesso 2025 jan 10]. Disponível em: https://cee.fiocruz.br/?q=jose-gomes-temporao-luiz-antonio-santini-novas-tecnologias-saude-desafio-do-acesso-com-equidade
Dee EC, Eala MAB, Robredo JPG, et al. Leveraging national and global political determinants of health to promote equity in cancer care. J Natl Cancer Inst. 2023;115(10):1157-63. doi: https://doi.org/10.1093/jnci/djad123
Santini LA. SUS: uma biografia - Lutas e conquistas da sociedade brasileira. Rio de Janeiro: Record; 2024.
Araújo LA, Teixeira LA. De doença da civilização a problema de saúde pública: câncer, sociedade e medicina brasileira no século XX. Bol Mus Para Emílio Goeldi Ciênc Hum [Internet]. 2017 [acesso 2024 jun 03];12(1):173-88. Disponível em: https://www.scielo.br/j/bgoeldi/a/wMKHKQbzr4fsRcTTgmkjgLK/?lang=pt DOI: https://doi.org/10.1590/1981.81222017000100010
Farmer P, Frenk J, Knaul FM, et al. Expansion of cancer care and control in countries of low and middle income: a call to action. Lancet. 2010;376(9747):1186-93. doi: https://doi.org/10.1016/s0140-6736(10)61152-x DOI: https://doi.org/10.1016/S0140-6736(10)61152-X
Dee EC, Eala MAB, Robredo JPG, et al. Leveraging national and global political determinants of health to promote equity in cancer care. J Natl Cancer Inst. 2023;115(10):1157-63. doi: https://doi.org/10.1093/jnci/djad123 DOI: https://doi.org/10.1093/jnci/djad123
Cavalli F. An appeal to world leaders: stop cancer now. The Lancet. 2013;381(9865):425-6. DOI: https://doi.org/10.1016/S0140-6736(13)60059-8
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