Metastatic Gestational Choriocarcinoma Mimicking an Incomplete Abortion: a Diagnostic Challenge Resolved with the EMA-CO Regimen
DOI:
https://doi.org/10.32635/2176-9745.RBC.2026v72n4.5605Keywords:
Uterine Hemorrhage, Choriocarcinoma, Chorionic Gonadotropin, Uterine NeoplasmsAbstract
Introduction: Choriocarcinoma is a rare disease of trophoblastic origin that is usually aggressive. Its monitoring and prognosis are based on constant measurements of human chorionic gonadotropin beta subunit, and early treatment has a significant influence on prognosis and survival. Case report: A 23-year-old female was admitted for vaginal bleeding. A transvaginal ultrasound was performed, which revealed endometrial thickening and significantly elevated beta-hCG. She was subsequently admitted with fever and suspected post-curettage endometritis, for which antibiotic treatment was initiated. However, given the persistence of signs suggestive of trophoblastic disease, a pelvic MRI was requested, which revealed a large expansive lesion. Conclusion: Choriocarcinoma is a highly malignant disease that requires timely and aggressive diagnosis and treatment. The treatment consisted in surgical excision of the tumour and chemotherapy.
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