Pediatric Brain Stem Tumors: Analysis of 25 Cases
DOI:
https://doi.org/10.32635/2176-9745.RBC.1985v31n4.3361Palabras clave:
Brain Neoplasms, VM26, CCNU, Vincristine, Childhood, Radiotherapy, Brain Stem TumorsResumen
The charts of twenty-five pediatria patients with brain stem tumors diagnosed between March 1977 and December 1980 have been reviewed. Ages of patients ranged from 22 months to 17 years. The use of computed tomography (CT) was found to have been valuable in diagnosis and follow-up, as well as in the design of radiation therapy portals. Radiotherapy and combination chemotherapy with VM26 (4'-1 demethyl-epipodophyllo-toxin B-D-thenyUdene glucoside) and CCNU (1-2-chloroethyl-methyl-3-Cyclohexyl-1-nitrosourea) were the treatment modalities employed. The three-year survival rate for this group of patients was 29%.
Descargas
Citas
Bilaniuk, L.T., Zimmerman, R.A., Littman, P., et al: Computed tomography of brain stem gliomas in children. Radiology, 1980; 134: 89. DOI: https://doi.org/10.1148/radiology.134.1.7350640
Gold, J.A. and Smith, K.Rj Childhood brain tumors — a 15 year survey of treatment in a University Pediatric Hospital. Southern Medicai Journal, 1975; 68 (11); 1337. DOI: https://doi.org/10.1097/00007611-197511000-00005
Cray, H. and Goss, C.M.: Anatomy of the human body. Philadelphia; Lea & Febiger, 1973; 802.
Hooper, R.; Intracranial tumors in childhood. Med. J. Aust, 1976; 1: 624. DOI: https://doi.org/10.5694/j.1326-5377.1976.tb140910.x
Jundt, S.; Tumeúrs de Ia fosse postérieure. Vie Médicale, 1972; 31 (2): 3661.
Kalifa, C. and Lemerle, J.; Tumeurs du trone cérébral. Protocole du Service de Pédiatrie de I' Institut Gustave-Roussy, 1977.
Kim, T.H., Chin, H.W., Poilan, S., et al: Radiotherapy of primary brain stem tumors. Int. Radiat. Oncol. Biol. Phys., 1980; 6; 51.
Lee, F.; Radiation of infratentorial and supratentorial brain stem tumors. J. Neurosurg., 1975; 43: 65. DOI: https://doi.org/10.3171/jns.1975.43.1.0065
Littman, P., Jarret, P., Bilaniuk, L.T., et al: Pediatric brain stem gliomas. Cancer, 1980; 45; 2787. DOI: https://doi.org/10.1002/1097-0142(19800601)45:11<2787::AID-CNCR2820451113>3.0.CO;2-V
Marsa, G.W., Probert, J.C., Rubinstein, L.J., et al: Radiation therapy in the treatment of childhood astrocytic gliomas. Cancer, 1973; 32: 646. DOI: https://doi.org/10.1002/1097-0142(197309)32:3<646::AID-CNCR2820320318>3.0.CO;2-Y
Panitch, H.S. and Berg, B.O. Brain stem tumors of childhood and adolescence. Amer. J. Dis. Child., 1970; 119 (6): 465. DOI: https://doi.org/10.1001/archpedi.1970.02100050467001
Pernkopf, E.: Atlas of topographical and applied human anatomy. Head and neck. Baltimore: Urban SrSchwarzenberg, 2ndedition, Vol. I, 1980: 86.
Rodary, Ch., Laplanche, A., Comnougue, C., et al: Établissement des courbes de survie: mise au point. Bull. Cancer (Paris), 1979; 66 (5): 575.
Schweisguth, O.: Tumeurs solides de 1'enfant. Paris: Flammarion Médecine-Sciences, 1979.
Sheline, G.E.: Radiation therapy of brain tumors. Cancer, 1977; 39: 873. DOI: https://doi.org/10.1002/1097-0142(197702)39:2+<873::AID-CNCR2820390725>3.0.CO;2-Y
Villani, R., Gaini, S.M. and Tomei, G.; Follow-up study of brain stem tumors in children. Child's brain, 1975; 1: 126. DOI: https://doi.org/10.1159/000119561
