High grade bifasic synovial sarcoma of the lung
DOI:
https://doi.org/10.32635/2176-9745.RBC.2003v49n3.2097Keywords:
Synovial Sarcoma, Lung Neoplasms, Immunohistochemistry, CytogeneticsAbstract
Synovial sarcoma is a malignant soft tissue neoplasm that occurs more often in young adults, affecting mainly the great joints. Primary lung sarcomas are extremely rare. Among the most common are leimyosarcoma, fibrosarcoma and haemangiopericytoma. The diagnosis of primary synovial is hampered because the difficulty between diagnosis of a primary and metastatic lesions. The translocation t(x;18) (p11;q11) is characteristic of synovial sarcomas and have been used mainly in the diagnosis of the monofasic type. The immunohistochemical and ultrastructural features are considered to be useful in diagnosing it too. The present report addresses a primary lung bifasic synovial sarcoma, confirmed by immunohistochemistry. The pacient was submited to surgery, radiation therapy and chemotherapy. Despite all the efforts she developed distant metastatic lesions and died.