Benefits and Safety of Physical Exercises in Patients with Bone Metastases: Systematic Literature Review and Meta-Analysis
DOI:
https://doi.org/10.32635/2176-9745.RBC.2022v68n4.2520Keywords:
physical therapy modalities, exercise, bone neoplasms, neoplasm metastasis, randomized controlled trialAbstract
Introduction: The life expectancy of individuals with metastatic cancer is increasing, but this group of patients is at considerable risk of having psychological and physical health problems. In this sense, physical exercise has been an ally in the treatment of patients with bone metastases. Objective: Systematic review and meta-analysis on the safety and benefits of physical exercise in patients with bone metastases. Method: Meta-analysis with bibliographic investigation carried out in the electronic databases PubMed, LILACS, PEDro and Embase. Results: Of the 396 studies, only 10 were included, with a total of 531 subjects. No adverse musculoskeletal effects were observed during the intervention, with exercise being significantly safe in individuals with bone metastases. There was no significant improvement in aerobic capacity, disease progression, quality of life, lean mass and body fat. Three of the studies included assessed pain during and after the intervention, showing an improvement in the pain score, as well as a decrease in use of analgesics in the intervention group. Conclusion: Therapy with aerobic and isometric exercises is safe in patients with bone metastases, in addition, it improves pain, but without significant increase of aerobic capacity, disease progression, body mass and quality of life.
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