Primary Malignant Melanoma of the Uterine Cervix: Rare Case Report

Authors

  • Carlos Anselmo Lima Universidade Federal de Sergipe (UFS), Hospital Universitário, Rede Ebserh. UFS, Programa de Pós-Graduação em Ciências da Saúde e Programa de Pós-Graduação Profissional em Gestão e Inovação Tecnológica em Saúde. Aracaju (SE), Brazil. https://orcid.org/0000-0003-4269-7320
  • Adriana Cardoso Batista Albuquerque Universidade Federal de Sergipe (UFS). Hospital Universitário, Rede Ebserh. UFS, Programa de Pós-Graduação em Ciências da Saúde. Aracaju (SE), Brazil. https://orcid.org/0000-0001-8046-7812
  • Érika de Abreu Costa Brito Universidade Federal de Sergipe (UFS), Hospital Universitário, Rede Ebserh. UFS, Programa de Pós-Graduação em Ciências da Saúde. Aracaju (SE), Brazil. https://orcid.org/0000-0003-0050-1799
  • Marcela Sampaio Lima Universidade Federal de Sergipe (UFS), Hospital Universitário, Rede Ebserh. UFS, Programa de Pós-Graduação em Ciências da Saúde. Aracaju (SE), Brazil. https://orcid.org/0000-0003-1738-4023

DOI:

https://doi.org/10.32635/2176-9745.RBC.2023v69n4.4410

Keywords:

cervix uteri, uterine cervical neoplasms, melanoma

Abstract

Introduction: Primary cervical melanoma is a rare and often challenging diagnosis, particularly in the presence of amelanotic lesions, where confirmation should be made through immunohistochemical methods. Despite aggressive treatment, the prognosis for this disease is typically poor. Case Report: A 79-year-old woman with a history of vaginal bleeding from a malignant cervical lesion. Initially, colposcopy examination revealed an ulcerated lesion of the exocervix, and biopsy confirmed a malignant neoplasm. However, following a radical abdominal hysterectomy, histopathological examination displayed a malignant epithelioid neoplasm, confirmed a malignant melanoma of the cervix through immunohistochemical assays. The patient received adjuvant chemotherapy and radiation therapy, but eventually experienced recurrence and died. Conclusion: The present report assesses a patient with an uncommon diagnosis of cervical melanoma, which, despite aggressive treatment, had an unfavorable outcome. However, thorough skin surveillance should be performed to correctly diagnose it as primary.

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Published

2023-12-14

How to Cite

1.
Lima CA, Cardoso Batista Albuquerque A, de Abreu Costa Brito Érika, Sampaio Lima M. Primary Malignant Melanoma of the Uterine Cervix: Rare Case Report. Rev. Bras. Cancerol. [Internet]. 2023 Dec. 14 [cited 2024 Nov. 22];69(4):e-204410. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/4410

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Section

CASE REPORT