Medication Review in Oncology Patients in Palliative Care: Pharmacist Assurance of Reasonable and Safe Use of Medications to Control Symptoms
DOI:
https://doi.org/10.32635/2176-9745.RBC.2024v70n3.4695Keywords:
Medication Review, Deprescriptions, Oncology, Palliative CareAbstract
Introduction: The medication review consists in analyzing the drugs utilized by a patient with the aim of reducing drug-related problems (DRP). Palliative treatment can cause adverse effects and contribute to polypharmacy. Therefore, the pharmacist plays a key role in ensuring the safety and reasonable use associated with pharmacological treatment. Objective: To analyze the medication review carried out in cancer patients undergoing exclusive palliative care at a reference hospital in Rio de Janeiro. Method: Observational, descriptive, retrospective quantitative approach study, involving patients admitted to the exclusive palliative care unit of the National Cancer Institute (INCA) whose pharmacological treatment was reviewed by the pharmacist from June 1, 2022 to May 31, 2023. Results: 171 patients, mostly females (n=114; 66.7%), aged 60 years or older (n=104; 60.8%) had their pharmacological treatment reviewed. More than half of them had at least one comorbidity (n=93; 54.4%), with predominance of those related to the circulatory system (n=68; 43.9%). The percentage of DRP and pharmaceutical interventions was similar (23.4%). The main DRP was the use of a medication the patient did not need (n=49; 53.3%) and most interventions excluded medications (n=55; 56.7%). There was acceptance of 93.5% of the interventions. Conclusion: The study highlights the importance of reviewing pharmacotherapy to optimize drug treatment in palliative care and reinforces the need to reduce the number of end-oflife prescribed medications.
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