Krukenberg Tumor in Long-Term Remission: Case Report
DOI:
https://doi.org/10.32635/2176-9745.RBC.2025v71n2.4926Keywords:
Krukenberg Tumor/diagnosis, Ovarian Diseases, Survival , Neoplasm MetastasisAbstract
Introduction: Krukenberg tumor is a rare and aggressive metastatic tumor that is part of the differential diagnosis of ovarian masses. It originates mainly from the gastrointestinal tract, especially the stomach and colon. Its median survival at diagnosis is 16 months. Case report: A 35-year-old healthy patient complained of lower abdominal pain and dyspareunia for one year, with a transvaginal ultrasound showing an extensive mass in the left ovary. Through the investigation, a colonoscopy was performed revealing rectosigmoid adenocarcinoma. The subsequent evaluation included analysis of the genetic panel, the result of which was negative, and the revelation of metastases in the liver, peritoneum, and ovary, the latter called Krukenberg tumor. After treatment involving chemotherapy, rectosigmoidectomy with lymphadenectomy and bilateral salpingo-oophorectomy, peritoneal cytoreduction, and hepatic metastasectomy surgeries, the latter two associated with hyperthermic intraperitoneal chemotherapy, the patient is asymptomatic, with quality of life and in complete remission five years after diagnosis. Conclusion: Case report of Krukenberg tumor with a longer remission time than described in the literature, possibly due to the combined therapies used and favorable molecular profile.
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