Alveolar Subtype Rhabdomyosarcoma of the Thenar Region with Axillary Lymph Node Invasion in an Adult: Case Report
DOI:
https://doi.org/10.32635/2176-9745.RBC.2025v71n2.4969Keywords:
Rhabdomyosarcoma, Soft Tissue Neoplasms, Adult, Surgical Amputation, Case ReportAbstract
Introduction: Rhabdomyosarcoma is a rare subtype of soft tissue malignancy whose cells are similar to myoblasts. It represents 1% of neoplasms in adults, with a poor prognosis and high recurrence rate. In this work, the objective is to report an ultra-rare case of alveolar rhabdomyosarcoma that affected the hand of an adult patient, in addition to conducting an integrative review of similar cases, given that primary cancers in the hand have an incidence of less than 1%. Case report: A 33-year-old woman sought clinical care due to the presence of a purplish, non-ulcerated lesion in the thenar region of her left hand, with lymphadenomegaly in the left axilla. Initially, the MRI revealed an expansive formation in the thenar region, in which the incisional biopsy and histochemical examination suggested high-grade alveolar rhabdomyosarcoma. Amputation of the first metacarpal of the left hand and axillary dissection of the affected lymph nodes were performed, in addition to SAIME chemotherapy interspersed with SAVAC every three weeks, and interval radiotherapy for six months. Treatment without complications and currently without recurrences. Conclusion: The reported case has an unusual anatomical presentation and age range for rhabdomyosarcoma, and the main aspects for favorable clinical follow-up are early diagnosis and multimodal therapy.
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