Photobiomodulation Associated or Not with Other Therapeutic Techniques in the Treatment of Post-Breast Cancer Lymphedema: Literature Systematic Review

Authors

DOI:

https://doi.org/10.32635/2176-9745.RBC.2025v71n3.5249

Keywords:

Breast Cancer Lymphedema, Mastectomy, Low-Level Light Therapy, Systematic Review

Abstract

Introduction: Breast cancer is the most common neoplasm among women in Brazil. Despite the various therapeutic approaches, surgical treatment is still indicated in many cases and usually includes a sentinel lymph node biopsy or axillary dissection. These techniques are associated with an increased risk of developing lymphedema. As a form of treatment for this chronic condition, photobiomodulation (PBM) has stood out for its effects in reducing inflammation, edema, and fibrosis, favoring the recovery of patients. Objective: To systematize the effects of PBM as a complementary therapy associated or not with other therapeutic techniques in post-breast cancer lymphedema. Method: Systematic review carried out on PubMed/MEDLINE, ScienceDirect, PEDro, BVS, and SciELO databases, using descriptors in Portuguese and English. Randomized clinical trials were included, without restrictions on language or year of publication. Results: Ten articles were included out of a total of 227 (all randomized clinical trials, PEDro score 6-9). Isolated PBM demonstrated efficacy in reducing limb volume, improving pain and functionality, with more evident effects in the first months and possible long-term maintenance. When associated with other therapies, the results were enhanced. Conclusion: PBM has shown to be a promising complementary approach for the management of post-breast cancer lymphedema, with beneficial results on symptoms. Further research is needed to standardize protocols that favor reproducibility and expand its application in clinical practice.

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Published

2025-08-20

How to Cite

1.
Reis LS dos, Silva TS da, Januário PG. Photobiomodulation Associated or Not with Other Therapeutic Techniques in the Treatment of Post-Breast Cancer Lymphedema: Literature Systematic Review. Rev. Bras. Cancerol. [Internet]. 2025 Aug. 20 [cited 2025 Dec. 15];71(3):e-255249. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/5249

Issue

Section

LITERATURE REVIEW