Labio Leporino/Paladar Hendido y Cáncer: una Conexión Verdadera

Autores/as

  • Alexandre Rezende Vieira University of Pittsburgh, School of Dental Medicine, Department of Oral & Craniofacial Sciences. Pittsburgh, PA, USA. https://orcid.org/0000-0003-3392-6881

DOI:

https://doi.org/10.32635/2176-9745.RBC.2021v67n4.2396

Palabras clave:

Labio Leporino, Fisura del Paladar, Neoplasias

Resumen

Multifactorial cleft lip and palate is relatively common in populations (1 in every 700 livebirths). Individuals born with clefts require lifelong treatment after initial surgical repair and data suggested that their lifespan is shorter, possibly due to cancer or psychiatric conditions. Molecular defects that alter facial development in utero appear to later in life predispose to cancer. Common polymorphisms in e-cadherin and an endoplasmic reticulum transmembrane sensor gene appear to hold the promise to be biomarkers that may help to define individual risks to cancer, in the presence or not of family history of clefts.

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Publicado

2021-09-29

Cómo citar

1.
Vieira AR. Labio Leporino/Paladar Hendido y Cáncer: una Conexión Verdadera. Rev. Bras. Cancerol. [Internet]. 29 de septiembre de 2021 [citado 3 de julio de 2024];67(4):e-062396. Disponible en: https://rbc.inca.gov.br/index.php/revista/article/view/2396

Número

Vol. 67 Núm. 4 (2021): oct./nov./dic.

Sección

ARTÍCULOS DE OPINIÓN

Licencia

Os direitos morais e intelectuais dos artigos pertencem aos respectivos autores, que concedem à RBC o direito de publicação.

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.