Angiogênese tumoral
DOI:
https://doi.org/10.32635/2176-9745.RBC.1994v40n3.2990Palabras clave:
Angiogênese, Fator Angiogênico, NeoplasiaResumen
Este artigo faz uma revisão de literatura a respeito do processo de angiogênese tumoral. Apresenta o histórico das investigações, os conceitos, e a importância da angiogênese em relação ao crescimento neoplásico. Aborda o mecanismo de formação deste processo e a participação dos fatores angiogênicos. Por fim, mostra a aplicação destes conhecimentos na prática clínica em relação ao diagnóstico, terapêutica e prognóstico.
Descargas
Citas
BLOOD CH, ZETTER BR. tumor interactions with vasculature: angiogenesis and tumor metastases. Biochim Biophys Acta 1990, 1032:89-118 DOI: https://doi.org/10.1016/0304-419X(90)90014-R
ALGIRE GH, CHALKLEY HW. Vascular reactions of normal and malignant tissues in vivo. I. Vascular reactions of mice to wounds and to normal and neoplastic implants. J. NatI Cancer Inst 1947, 6:73-85. DOI: https://doi.org/10.1093/jnci/6.1.73
GEENE, HS. Heterologus transplantation of mammalian tumors. J Exp Med 1961, 73:461-480. DOI: https://doi.org/10.1084/jem.73.4.461
FOLKAMN J, MERLER E, ALBERNATHY C, WILLIAMS, G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med 1971, 33:275-280. DOI: https://doi.org/10.1084/jem.133.2.275
GIMBRONE MA, LEAPMAN S, COTRAN RS, FOLKMAN J. J NatI Cancer Inst 1973, 50:219.228. DOI: https://doi.org/10.1093/jnci/50.1.219
FOLKMAN J. Tumor angiogenesis: Therapeutic implications. N EngI J Med 1971; 285:1182-1186. DOI: https://doi.org/10.1056/NEJM197111182852108
FOLKMAN J. Tumor angiogenesis. Adv Câncer Res 1985, 43:175-179. DOI: https://doi.org/10.1016/S0065-230X(08)60946-X
FOLKMAN J, WATSON K, INGBERG D, HANABAN D. Induction of angiogenese during the transition from hiperplasia to neoplasia. Nature 1989; 339:58-61. DOI: https://doi.org/10.1038/339058a0
FOLKMAN J, KLAGSBURN M. Angiogenic Factors. Science 1987, 235:442-447. DOI: https://doi.org/10.1126/science.2432664
HERLYN M, MALKOWICZ SB. Regulatory pathways in tumor growth and invasion. Lab Invest 1991, 65:262.271.
PETERSON H-l. Tumor Blood Circulation: angiogenesis, vascular morphology, and blood flow of experimental and human tumors. Boca Raton-Florida, CRC press, 1979.
STRICKLAND B. The value of arteriography in the diagnosis of bone tumors. Br J Radiol 1969, 32:705-713. DOI: https://doi.org/10.1259/0007-1285-32-383-705
GAMMILL SL, SHIPKEY RB, HIMMELFARB EH, PARVEY LS, RABINOWITZ JG. Roentgenelogy-pathology correlative study of neovascularity. Am J Radiol 1976, 126:376-385. DOI: https://doi.org/10.2214/ajr.126.2.376
RIBEIRO JAC. Estudo dos fluxos vasculares dos tumors ovarianos através do doppler colorido transvaginal e sua importância no diagnóstico ultrassográfico do câncer de ovário. Tese de Doutorado, FMRP-USP, 1993.
GAGLIARDI A, HADD H, COLLINS DC. Inhibition of angiogenesis by suramin. Cancer Res 52: 5073-5975, 1992.
JIKIHARA H, TERADA N, YAMAMOTO CT, NISHIKAWA Y, TANIZAWAO, MATSUMOTO K, TERAKAWA N. Inibitory effect of medroxyprogesterone acetate on angiogenesis induced by human endometrial cancer. Am J Obstet Gynecol 1992, 167:207-211. DOI: https://doi.org/10.1016/S0002-9378(11)91659-7
PIENTA KJ, NGUYEN NM, LEHR JC. Treatment of prostate cancer in the rat with synthetic retinoid fenretinide. Cancer Res 1993, 53:224.226.
WEIDNER N, FOLKMAN J, POZZA F, PIERANTONIO B, ALLRED EN, MOORE D, MELI S, GASPARINI G. Tumor angiogenesis: A newsignificant and independent prognostic indicator in early-stage breast carcinoma. J. NatI Cancer Inst 1992, 84: 1875-1887. DOI: https://doi.org/10.1093/jnci/84.24.1875
