Melanoma de Mucosa Oral, Genital e Anorretal
DOI:
https://doi.org/10.32635/2176-9745.RBC.2000v46n2.3415Palabras clave:
Melanoma, Membrana Mucosa, Oral, Genital, AnorretalResumen
Entre 1970 e 1997, 411 pacientes com diagnóstico de melanoma foram atendidos no Hospital São Judas Tadeu de Barretos. Destes, 7 (1,7%) eram de mucosa e os respectivos prontuários foram analisados para este trabalho. Quanto à localização, eram anorretal; 2 eram vulvovaginal, e 1 localizava-se no palato; havia seis pacientes do sexo feminino e um masculino variando as idades de 31 a 81 anos (média = 61 anos). Apenas um paciente apresentou tumor localizado (está com quase 5 anos de sobrevida), 4 tinham doença regional (todos faleceram antes de 3 anos após o diagnóstico) e dois tinham metástases (óbitos ocorridos antes de um ano após diagnóstico). Os tratamentos variaram de conformidade com o estadiamento da doença. Os dados evidenciam o prognóstico ruim da moléstia, que se apresenta, usualmente em estádios avançados e, freqüentemente, com metástases.
Descargas
Citas
PACK, GT; DAVIS, J; OPPENHEIM, A. - The relation of race and complexion to the incidence of males and melanomas. Ann NYAcad Sei; 100: 719-742, 1963. DOI: https://doi.org/10.1111/j.1749-6632.1963.tb42886.x
ROGERS, RS and GIBSON LE - Mucosal, genital and unusual clinical variants of melanoma. Mayo Clin Proc; 72: 362-366, 1997. DOI: https://doi.org/10.4065/72.4.362
WEINSTOCK, MA - Epidemiology and prognosis of anorectal melanoma. Gastroenterology; 104: 174-178, 1993.
CHANG, AE; KARNELL, LH; MENCK, HR – The national cancer date base report on cutaneous and noncutaneous melanoma- A summary of 84.836 cases from the past decade. Cancer, 15: 1664-1678, 1998. DOI: https://doi.org/10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G
CAGIR, B.; WHITEFORD, MH.; TOPHAM, A.; RAKINIC, J.; FRY RD. - Changing epidemiology of anorectal melanoma. Dis Colon Rectum; 42: 1203-1208, 1999. DOI: https://doi.org/10.1007/BF02238576
DELIKARIS, P; KOUTMERIDIS, D; TSONIS, G; ASIMAKI, A; MOURATIDOU, D. – Synchronous anorectal malignant melanoma and rectal adenocarcinoma. Dis Colon Rectum; 40: 105-108, 1997. DOI: https://doi.org/10.1007/BF02055691
THIBAULT, C; SAGAR, P; NIVATVONGS, S; ILSRUP, DM; WOLFF, BG. - Anorectal melanoma — an incurable disease?. Dis Colon Rectum; 40: 661-668, 1997. DOI: https://doi.org/10.1007/BF02140894
WONG, JH; CAGLE, LA; STORM, FK; MORTON, DL. - Natural history of surgically treated mucosal melanoma. Am J Surg, 154: 54-57, 1987. DOI: https://doi.org/10.1016/0002-9610(87)90289-3
SCOTTO, J; FRAUMENI, JF; LEE. JAH. - Melanoma of the eye and other nonocutaneous sites: Epidemiological aspects. JNCI; 56: 489-491, 1976. DOI: https://doi.org/10.1093/jnci/56.3.489
CHAUDHRY, AP; HAMPEL, A; GORLIN, K. - Primary malignant of the oral cavity. Cancer; 11: 923-928, 1958. DOI: https://doi.org/10.1002/1097-0142(195809/10)11:5<923::AID-CNCR2820110507>3.0.CO;2-1
ROSAI, J. — Ackerman’s Surgical Pathology, Eighth Edition, Mosby, 1996.
ROSS, M; PEZZI C; PEZZI T; MEURER D; HICKEY R; BALCH C. - Patterns of failure in anorectal melanoma. 125: 313-316, 1990. DOI: https://doi.org/10.1001/archsurg.1990.01410150035007
GARNICK, M; LOKICH, JJ. - Primary malignant melanoma of the rectum: rationale for conservative surgical management. J Surg Oncol; 10: 529-531. 1978. DOI: https://doi.org/10.1002/jso.2930100609
WANEBO, HJ; WOODRUFF, JM; FARR GH, QUAN, SH. - Anorectal Melanoma. Câncer, 47: 1891-1900, 1981. DOI: https://doi.org/10.1002/1097-0142(19810401)47:7<1891::AID-CNCR2820470730>3.0.CO;2-K
MCKINNON, G; KOKAL, WA; NEIFELD, JP; KAY S. - Natural history and treatment of mucosal melanoma. J Surg Oncol; 41: 222-225, 1989. DOI: https://doi.org/10.1002/jso.2930410406
KATO, T; TAKEMATSU, H; TOMITA, Y; TAKAHASHI, M; ABE, R. - Malignant melanoma of mucous membranes. Arch Dermatoh, 123: 216-220, 1987. DOI: https://doi.org/10.1001/archderm.123.2.216
TAKAGI, M; ISHIKAWA, G; MORI, W. - Primary malignant melanoma of the oral cavity in Japan. Cancer, 34: 359-370, 1987. DOI: https://doi.org/10.1002/1097-0142(197408)34:2<358::AID-CNCR2820340221>3.0.CO;2-D
HARWOOD, AR; CUMMINGS. BJ. Radiotherapy for mucosal melanomas. Int. J. Radiat. Oncol. Biol. Phys; 8: 1121-1126, 1982. DOI: https://doi.org/10.1016/0360-3016(82)90058-X
GUTMAN, M; INBAR, M; CHAITCHIC, S; MERHAV, A; PAUSNER, D; SKOZNIK, Y; ILIE, B; ROZIN, RR; KLAUSNER, JM. – Malignant melanoma of the mucous membranes. Eur. J. Surg. Oncol.; , 18: 307-312, 1992.
MILLER BJ; RUTHERFORD LF; MCLEOD GRC; COHEN JR — Where the sun never shines: anorectal melanoma. Aust NZ J Surg, 67: 846-848, 1997. DOI: https://doi.org/10.1111/j.1445-2197.1997.tb07609.x
GOLDMAN, S; GLIMELIUS, B; PAHLMAN, L. - Anorectal malignant melanoma in Sweden: report of 49 patients. Dis. Colon Rectum; 33: 874-877, 1990. DOI: https://doi.org/10.1007/BF02051925
WEINSTOCK, MA. — Epidemiology and prognosis of anorectal melanoma. Gastroenterology; 104: 174-178, 1993. DOI: https://doi.org/10.1016/0016-5085(93)90849-8
SLINGLUFF, CL JR; VOLLMER, RT; SEIGLER, HF. - Anorectal Melanoma: clinical characteristics and results of surgical management in twenty-four patients. Surgery; 107: 1-9, 1990.
GOMES, UA; MAUAD, EC. - Knowledge of and access to screening in women with carcinoma of the cervix in Brazil. Rev. Bras. Cancerol; 38 (2/3): 99- 102, 1992.
CRAIG, L; SLINGLUFF JR; VOLLMER, R; SEIGLER, HF. - Anorectal melanoma: Clinical characteristics and results of surgical management in twenty-four patients. Surgery; 107: 1-9, 1990.
BRADGATE, MG; ROLLASON.TP; MCCONKEY CC; POWELL, J. - Malignant melanoma of the vulva: a clinicopathological study of 50 women. Br J Obstet Gynaecok 97: 124-133, 1990. DOI: https://doi.org/10.1111/j.1471-0528.1990.tb01737.x
CHUNG, AF; WOODRUFF, JM; LEWIS, JL JR. — Malignant melanoma of the vulva - A reports of 44 cases. Obstet Gynecol, 45: 638-646, 1975. DOI: https://doi.org/10.1097/00006250-197506000-00008
RAGNARSSON - OLDING, B; JOHANSSON, H; RUTGUIST, LE; RINBORG, V. – Malignant melanoma of the vulva and vagina. Trends in incidence age distribution and long-term surgical among 245 consecutive cases in Sweden. Cancer, 71: 1893-1897, 1993. DOI: https://doi.org/10.1002/1097-0142(19930301)71:5<1893::AID-CNCR2820710528>3.0.CO;2-7
MORROW, CP; Dl SAIA, PJ. - Malignant melanoma of the female genitalia: a clinical analysis. Obstet Gynecol Surg, 31: 233-271, 1976. DOI: https://doi.org/10.1097/00006254-197604000-00001
PHILLIPS, GL; TWIGGS, LB; OKAGAKI, T. - Vulvar melanoma: a microstaging study. Gynecol Oncol; 14: 80-88, 1981. DOI: https://doi.org/10.1016/0090-8258(82)90053-1
RABER, G; MEMPEL, V; JACKISCH, C; HUNDEIKER, M; HEINECKE, A; KÜREL, R; GLAUBITZ, M; ROMPEL, R; SCHNEIDER, HPG. Malignant melanoma of the vulva. Report of 89 patients. Cancer, 78: 2353-2358, 1996. DOI: https://doi.org/10.1002/(SICI)1097-0142(19961201)78:11<2353::AID-CNCR13>3.0.CO;2-#
PILSKJN, ME. - Malignant melanoma of the oral cavity. In: Clark, WH Jr, Goldman, LI; Mastrangelo, MJ eds, Human Malignant Melanoma. New York: Grune & Stratton: 125-137, 1979.
PRESENT, CA. - Malignant melanoma of mucosal site. In: Constanzi JJ ed, Malignant Melanoma. I. Dordrecht, Netherlands: Martinus Nijhoff Publishers; 55-83, 1983. DOI: https://doi.org/10.1007/978-1-4613-3900-7_4
DAS GUPTA, TK; BOWDEN, L; BERG, JW. - Malignant melanoma of unknown primary origin. Surg Gynecol Obstet; 112: 341-345, 1963.