Comparación Dosimétrica entre Técnicas de Planificación de Radioterapia para el Cáncer de Mama Izquierdo

Autores/as

DOI:

https://doi.org/10.32635/2176-9745.RBC.2023v69n3.4020

Palabras clave:

radioterapia conformacional, radioterapia de intensidad modulada, neoplasias de la mama, dosis de radiación

Resumen

Introducción: La radioterapia se utiliza en el tratamiento del cáncer de mama. En la planificación de la radioterapia, existen formas de desarrollar el plan de tratamiento, como la radioterapia conformacional 3D (3D-CRT), la radioterapia de intensidad modulada (IMRT) y la arcoterapia volumétrica modulada (VMAT). Objetivo: Comparar las dosis en órganos de riesgo y en el volumen blanco de tratamiento con diferentes técnicas de planificación: 3D-CRT, IMRT, VMAT y VMAT modificada para el tratamiento del cáncer de mama en un fantoma antropomórfico. Método: El plan de tratamiento se realizó en el sistema Eclipse™ v.15.6 de Varian a partir de imágenes de TC adquiridas del fantoma. La dosis de prescripción establecida fue de 45 Gy en 25 fracciones de 1,8Gy/día. Resultados: En cuanto a la cobertura del volumen blanco de planificación (VBP), las técnicas 3D-CRT (filtro - FILTRO y field-in-field – FIF) demostraron una cobertura inferior en comparación con los planes IMRT y VMAT. El plan 3D-RCT-FIF mostró mayor homogeneidad en comparación con el 3D-RCT-FILTRO. Para el pulmón contralateral, los planes 3D-CRT (FIF, FILTER) obtuvieron mejores restricciones en comparación con los otros planes. En la exposición cardiaca, los planes 3D-CRT (FIF, FILTER) mostraron mayores beneficios en comparación con las técnicas IMRT, VMAT y VMAT modificada. Conclusión: Las técnicas convencionales de 3D-CRT (FIF, FILTER) mostraron dosis más bajas en los órganos de riesgo. Sin embargo, las técnicas IMRT y VMAT obtuvieron una mejor homogeneidad y conformidad de la dosis distribuida en el VBP en comparación con las técnicas convencionales.

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Publicado

2023-07-13

Cómo citar

1.
Prandi TMD, Zaias H, Silva C da, Müller J dos S, Blasius LP da S, Dorow PF. Comparación Dosimétrica entre Técnicas de Planificación de Radioterapia para el Cáncer de Mama Izquierdo. Rev. Bras. Cancerol. [Internet]. 13 de julio de 2023 [citado 3 de julio de 2024];69(3):e-074020. Disponible en: https://rbc.inca.gov.br/index.php/revista/article/view/4020

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ARTÍCULO ORIGINAL